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AKAP1 enhances glycogen accumulation and hepatocarcinogenesis through YTHDF2-mediated G6PC mRNA decay.

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Title: AKAP1 enhances glycogen accumulation and hepatocarcinogenesis through YTHDF2-mediated G6PC mRNA decay.
Authors: Yang T; Department of Interventional Radiology, Tangdu Hospital, Fourth Military Medical University, Xi'an, China., Zhang J; Department of Thoracic Surgery, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China., Zhao Z; Department of Interventional Radiology, Tangdu Hospital, Fourth Military Medical University, Xi'an, China., Cheng S; College of Life Sciences, Northwest University, Xi'an, China., Yan Z; Department of General Surgery, Tangdu Hospital, Fourth Military Medical University, Xi'an, China., Wang W; College of Life Sciences, Northwest University, Xi'an, China., Wang G; State Key Laboratory of Holistic Integrative Management of Gastrointestinal Cancers and Department of Physiology and Pathophysiology, Fourth Military Medical University, Xi'an, China., Zhang R; Department of Cell Biology, National Translational Science Center for Molecular Medicine, Fourth Military Medical University, Xi'an, China., Zhang Z; Department of Interventional Radiology, Tangdu Hospital, Fourth Military Medical University, Xi'an, China., Yuan P; Department of Nuclear Medicine, Tangdu Hospital, Fourth Military Medical University, Xi'an, China., Zheng X; Department of Infectious Diseases, Tangdu Hospital, Fourth Military Medical University, Xi'an, China., Zhang H; Department of Interventional Radiology, Tangdu Hospital, Fourth Military Medical University, Xi'an, China. zhhxtdjr@163.com., Li J; State Key Laboratory of Holistic Integrative Management of Gastrointestinal Cancers and Department of Physiology and Pathophysiology, Fourth Military Medical University, Xi'an, China. lijibin2006@163.com., Xing J; State Key Laboratory of Holistic Integrative Management of Gastrointestinal Cancers and Department of Physiology and Pathophysiology, Fourth Military Medical University, Xi'an, China. xingjl@fmmu.edu.cn.
Source: Signal transduction and targeted therapy [Signal Transduct Target Ther] 2026 Jun 16; Vol. 11 (1). Date of Electronic Publication: 2026 Jun 16.
Publication Type: Journal Article
Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101676423 Publication Model: Electronic Cited Medium: Internet ISSN: 2059-3635 (Electronic) Linking ISSN: 20593635 NLM ISO Abbreviation: Signal Transduct Target Ther Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: AKAP1 enhances glycogen accumulation and hepatocarcinogenesis through YTHDF2-mediated G6PC mRNA decay.
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  Data: <searchLink fieldCode="AU" term="%22Yang+T%22">Yang T</searchLink>; Department of Interventional Radiology, Tangdu Hospital, Fourth Military Medical University, Xi'an, China.<br /><searchLink fieldCode="AU" term="%22Zhang+J%22">Zhang J</searchLink>; Department of Thoracic Surgery, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.<br /><searchLink fieldCode="AU" term="%22Zhao+Z%22">Zhao Z</searchLink>; Department of Interventional Radiology, Tangdu Hospital, Fourth Military Medical University, Xi'an, China.<br /><searchLink fieldCode="AU" term="%22Cheng+S%22">Cheng S</searchLink>; College of Life Sciences, Northwest University, Xi'an, China.<br /><searchLink fieldCode="AU" term="%22Yan+Z%22">Yan Z</searchLink>; Department of General Surgery, Tangdu Hospital, Fourth Military Medical University, Xi'an, China.<br /><searchLink fieldCode="AU" term="%22Wang+W%22">Wang W</searchLink>; College of Life Sciences, Northwest University, Xi'an, China.<br /><searchLink fieldCode="AU" term="%22Wang+G%22">Wang G</searchLink>; State Key Laboratory of Holistic Integrative Management of Gastrointestinal Cancers and Department of Physiology and Pathophysiology, Fourth Military Medical University, Xi'an, China.<br /><searchLink fieldCode="AU" term="%22Zhang+R%22">Zhang R</searchLink>; Department of Cell Biology, National Translational Science Center for Molecular Medicine, Fourth Military Medical University, Xi'an, China.<br /><searchLink fieldCode="AU" term="%22Zhang+Z%22">Zhang Z</searchLink>; Department of Interventional Radiology, Tangdu Hospital, Fourth Military Medical University, Xi'an, China.<br /><searchLink fieldCode="AU" term="%22Yuan+P%22">Yuan P</searchLink>; Department of Nuclear Medicine, Tangdu Hospital, Fourth Military Medical University, Xi'an, China.<br /><searchLink fieldCode="AU" term="%22Zheng+X%22">Zheng X</searchLink>; Department of Infectious Diseases, Tangdu Hospital, Fourth Military Medical University, Xi'an, China.<br /><searchLink fieldCode="AU" term="%22Zhang+H%22">Zhang H</searchLink>; Department of Interventional Radiology, Tangdu Hospital, Fourth Military Medical University, Xi'an, China. zhhxtdjr@163.com.<br /><searchLink fieldCode="AU" term="%22Li+J%22">Li J</searchLink>; State Key Laboratory of Holistic Integrative Management of Gastrointestinal Cancers and Department of Physiology and Pathophysiology, Fourth Military Medical University, Xi'an, China. lijibin2006@163.com.<br /><searchLink fieldCode="AU" term="%22Xing+J%22">Xing J</searchLink>; State Key Laboratory of Holistic Integrative Management of Gastrointestinal Cancers and Department of Physiology and Pathophysiology, Fourth Military Medical University, Xi'an, China. xingjl@fmmu.edu.cn.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Nature+Publishing+Group%22">Nature Publishing Group </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>101676423 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>2059-3635 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2220593635%22">20593635 </searchLink><i>NLM ISO Abbreviation: </i>Signal Transduct Target Ther <i>Subsets: </i>MEDLINE
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              Text: 2026 Jun 16
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