Target receptor expression dictates the selective intra-tumoral targeting of CD8+ T cells by eciskafusp alfa in matched PBMCs and TILs from CPI-naïve patients.

Saved in:
Bibliographic Details
Title: Target receptor expression dictates the selective intra-tumoral targeting of CD8+ T cells by eciskafusp alfa in matched PBMCs and TILs from CPI-naïve patients.
Authors: Manchala A; Roche Pharma Research and Early Development, Roche Innovation Center Zürich, Schlieren, Switzerland.; Institute of Experimental Immunology, University of Zurich, Zürich, Switzerland., Varypataki EM; Roche Pharma Research and Early Development, Roche Innovation Center Zürich, Schlieren, Switzerland., Charo J; Roche Pharma Research and Early Development, Roche Innovation Center Zürich, Schlieren, Switzerland., Umaña P; Roche Pharma Research and Early Development, Roche Innovation Center Zürich, Schlieren, Switzerland., Klein C; Roche Pharma Research and Early Development, Roche Innovation Center Zürich, Schlieren, Switzerland.; Department of Biochemistry, Faculty of Chemistry and Pharmacy, Ludwig Maximilians University of Munich, Munich, Germany., Codarri Deak L; Roche Pharma Research and Early Development, Roche Innovation Center Zürich, Schlieren, Switzerland.
Source: Frontiers in immunology [Front Immunol] 2026 Jun 01; Vol. 17, pp. 1843841. Date of Electronic Publication: 2026 Jun 01 (Print Publication: 2026).
Publication Type: Journal Article
Journal Info: Publisher: Frontiers Research Foundation] Country of Publication: Switzerland NLM ID: 101560960 Publication Model: eCollection Cited Medium: Internet ISSN: 1664-3224 (Electronic) Linking ISSN: 16643224 NLM ISO Abbreviation: Front Immunol Subsets: MEDLINE
Database: MEDLINE Ultimate
Full text is not displayed to guests.
FullText Links:
  – Type: pdflink
Text:
  Availability: 1
Header DbId: mdl
DbLabel: MEDLINE Ultimate
An: 42305548
AccessLevel: 2
PubType: Academic Journal
PubTypeId: academicJournal
PreciseRelevancyScore: 0
IllustrationInfo
Items – Name: Title
  Label: Title
  Group: Ti
  Data: Target receptor expression dictates the selective intra-tumoral targeting of CD8<superscript>+</superscript> T cells by eciskafusp alfa in matched PBMCs and TILs from CPI-naïve patients.
– Name: Author
  Label: Authors
  Group: Au
  Data: <searchLink fieldCode="AU" term="%22Manchala+A%22">Manchala A</searchLink>; Roche Pharma Research and Early Development, Roche Innovation Center Zürich, Schlieren, Switzerland.; Institute of Experimental Immunology, University of Zurich, Zürich, Switzerland.<br /><searchLink fieldCode="AU" term="%22Varypataki+EM%22">Varypataki EM</searchLink>; Roche Pharma Research and Early Development, Roche Innovation Center Zürich, Schlieren, Switzerland.<br /><searchLink fieldCode="AU" term="%22Charo+J%22">Charo J</searchLink>; Roche Pharma Research and Early Development, Roche Innovation Center Zürich, Schlieren, Switzerland.<br /><searchLink fieldCode="AU" term="%22Umaña+P%22">Umaña P</searchLink>; Roche Pharma Research and Early Development, Roche Innovation Center Zürich, Schlieren, Switzerland.<br /><searchLink fieldCode="AU" term="%22Klein+C%22">Klein C</searchLink>; Roche Pharma Research and Early Development, Roche Innovation Center Zürich, Schlieren, Switzerland.; Department of Biochemistry, Faculty of Chemistry and Pharmacy, Ludwig Maximilians University of Munich, Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Codarri+Deak+L%22">Codarri Deak L</searchLink>; Roche Pharma Research and Early Development, Roche Innovation Center Zürich, Schlieren, Switzerland.
– Name: TitleSource
  Label: Source
  Group: Src
  Data: <searchLink fieldCode="JN" term="%22101560960%22">Frontiers in immunology</searchLink> [Front Immunol] 2026 Jun 01; Vol. 17, pp. 1843841. <i>Date of Electronic Publication: </i>2026 Jun 01 (<i>Print Publication: </i>2026).
– Name: TypePub
  Label: Publication Type
  Group: TypPub
  Data: Journal Article
– Name: TitleSource
  Label: Journal Info
  Group: Src
  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Frontiers+Research+Foundation]%22">Frontiers Research Foundation] </searchLink><i>Country of Publication: </i>Switzerland <i>NLM ID: </i>101560960 <i>Publication Model: </i>eCollection <i>Cited Medium: </i>Internet <i>ISSN: </i>1664-3224 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2216643224%22">16643224 </searchLink><i>NLM ISO Abbreviation: </i>Front Immunol <i>Subsets: </i>MEDLINE
PLink https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=42305548
RecordInfo BibRecord:
  BibEntity:
    Identifiers:
      – Type: doi
        Value: 10.3389/fimmu.2026.1843841
    Languages:
      – Code: eng
        Text: English
    PhysicalDescription:
      Pagination:
        StartPage: 1843841
    Titles:
      – TitleFull: Target receptor expression dictates the selective intra-tumoral targeting of CD8+ T cells by eciskafusp alfa in matched PBMCs and TILs from CPI-naïve patients.
        Type: main
  BibRelationships:
    HasContributorRelationships:
      – PersonEntity:
          Name:
            NameFull: Manchala A
      – PersonEntity:
          Name:
            NameFull: Varypataki EM
      – PersonEntity:
          Name:
            NameFull: Charo J
      – PersonEntity:
          Name:
            NameFull: Umaña P
      – PersonEntity:
          Name:
            NameFull: Klein C
      – PersonEntity:
          Name:
            NameFull: Codarri Deak L
    IsPartOfRelationships:
      – BibEntity:
          Dates:
            – D: 01
              M: 06
              Text: 2026 Jun 01
              Type: published
              Y: 2026
          Identifiers:
            – Type: issn-electronic
              Value: 1664-3224
          Numbering:
            – Type: volume
              Value: 17
          Titles:
            – TitleFull: Frontiers in immunology
              Type: main
ResultId 1