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Glycogen Synthase Kinase-3β Inhibition Ameliorates Synaptic and Mitochondrial Dysfunction in a Sporadic Alzheimer's Disease-Like Model.

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Title: Glycogen Synthase Kinase-3β Inhibition Ameliorates Synaptic and Mitochondrial Dysfunction in a Sporadic Alzheimer's Disease-Like Model.
Authors: Wang YH; Department of Neurology, Hunan Provincial Hospital of Integrated Traditional Chinese and Western Medicine, Changsha, Hunan, China.; Lushan Road No. 58, Yuelu District, Changsha, 410000, Hunan, China., Ding PL; First Clinical Medical College, Shandong University of Traditional Chinese Medicine, Jinan, Shandong, China.; Jingshi Road NO.16369, Lixia District, Jinan, 250014, Shandong, China., Qin H; Neck-Shoulder and Lumbocrural Pain Hospital of Shandong First Medical University, Jinan, Shandong, China.; Jingshi Road NO.18877, Lixia District, Jinan, 250014, Shandong, China., Zhang KX; First Clinical Medical College, Shandong University of Traditional Chinese Medicine, Jinan, Shandong, China.; Jingshi Road NO.16369, Lixia District, Jinan, 250014, Shandong, China., Ge JW; Hunan Academy of Chinese Medicine, Changsha, Hunan, China. 40831556@qq.com.; Yuehua Road No. 142, Yuelu District, Changsha, 410000, Hunan, China. 40831556@qq.com., Wu DH; Department of Neurology, Hunan Provincial Hospital of Integrated Traditional Chinese and Western Medicine, Changsha, Hunan, China. 893049352@qq.com.; Lushan Road No. 58, Yuelu District, Changsha, 410000, Hunan, China. 893049352@qq.com., Xie L; Department of Neurology, Hunan Provincial Hospital of Integrated Traditional Chinese and Western Medicine, Changsha, Hunan, China. 1289398706@qq.com.; Lushan Road No. 58, Yuelu District, Changsha, 410000, Hunan, China. 1289398706@qq.com., Liang K; Neck-Shoulder and Lumbocrural Pain Hospital of Shandong First Medical University, Jinan, Shandong, China. 2678617548@qq.com.; Jingshi Road NO.18877, Lixia District, Jinan, 250014, Shandong, China. 2678617548@qq.com.
Source: Molecular neurobiology [Mol Neurobiol] 2026 Jun 17; Vol. 63 (1). Date of Electronic Publication: 2026 Jun 17.
Publication Type: Journal Article
Journal Info: Publisher: Humana Press Country of Publication: United States NLM ID: 8900963 Publication Model: Electronic Cited Medium: Internet ISSN: 1559-1182 (Electronic) Linking ISSN: 08937648 NLM ISO Abbreviation: Mol Neurobiol Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1559-1182
DOI:10.1007/s12035-026-05970-1