Developing low-carbon salbutamol MDI: assessment of relative bioavailability and pharmacodynamic relative potency of salbutamol MDI with propellant HFA-152a.

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Title: Developing low-carbon salbutamol MDI: assessment of relative bioavailability and pharmacodynamic relative potency of salbutamol MDI with propellant HFA-152a.
Authors: Moreira S; Clinical Pharmacology Modeling & Simulation, GSK, Collegeville, Pennsylvania, USA sebastian.a.moreira@gsk.com., Clow L; Respiratory, Immunology & Inflammation Research Unit Medicine Development Leaders, GSK, Stevenage, UK., Coles-Piper E; Global Clinical Operations Development - R&D, GSK, London, UK., Donald A; Development Biostatistics, GSK, Upper Providence, Pennsylvania, USA., Janson C; Department of Medical Sciences, Respiratory, Allergy and Sleep Research, Uppsala University, Uppsala, Sweden., Singh D; Centre for Respiratory Medicine and Allergy, Institute of Inflammation and Repair, Manchester University NHS Foundation Trust, The University of Manchester, Manchester, UK.; Medicines Evaluation Unit, Manchester, UK., Slade D; Respiratory Clinical Research Unit, GSK, Collegeville, Pennsylvania, USA., Tiwari P; Statistics (R&D), GSK, Bengaluru, Karnataka, India., Weng S; Respiratory Biostatistics, GSK, Stevenage, UK., Plank M; Global Medical Affairs, General Medicines, GSK, Gold Coast, Queensland, Australia.
Source: BMJ open respiratory research [BMJ Open Respir Res] 2026 Jun 17; Vol. 13 (1). Date of Electronic Publication: 2026 Jun 17.
Publication Type: Journal Article; Clinical Trial, Phase I; Randomized Controlled Trial
Journal Info: Publisher: BMJ Publishing Group Ltd & British Thoracic Society Country of Publication: England NLM ID: 101638061 Publication Model: Electronic Cited Medium: Internet ISSN: 2052-4439 (Electronic) Linking ISSN: 20524439 NLM ISO Abbreviation: BMJ Open Respir Res Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:2052-4439
DOI:10.1136/bmjresp-2025-004036