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Sex-linked helicases DDX3X and DDX3Y regulate G-quadruplex-associated stress in neurons.

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Title: Sex-linked helicases DDX3X and DDX3Y regulate G-quadruplex-associated stress in neurons.
Authors: Diaz Escarcega R; Department of Neurology, McGovern Medical School, The University of Texas Health Science Center at Houston, Houston, TX, USA.; The BRAINS Research Laboratory, the Department of Neurology, University of Texas McGovern Medical School, Houston, TX, USA., M J VK; Department of Neurology, McGovern Medical School, The University of Texas Health Science Center at Houston, Houston, TX, USA.; The BRAINS Research Laboratory, the Department of Neurology, University of Texas McGovern Medical School, Houston, TX, USA., Arizmendez A; Department of Neurology, McGovern Medical School, The University of Texas Health Science Center at Houston, Houston, TX, USA.; The BRAINS Research Laboratory, the Department of Neurology, University of Texas McGovern Medical School, Houston, TX, USA., Tan C; Department of Neurology, McGovern Medical School, The University of Texas Health Science Center at Houston, Houston, TX, USA.; The BRAINS Research Laboratory, the Department of Neurology, University of Texas McGovern Medical School, Houston, TX, USA., Urayama A; Department of Neurology, McGovern Medical School, The University of Texas Health Science Center at Houston, Houston, TX, USA.; The BRAINS Research Laboratory, the Department of Neurology, University of Texas McGovern Medical School, Houston, TX, USA., Marrelli SP; Department of Neurology, McGovern Medical School, The University of Texas Health Science Center at Houston, Houston, TX, USA.; The BRAINS Research Laboratory, the Department of Neurology, University of Texas McGovern Medical School, Houston, TX, USA., Morales R; Department of Neurology, McGovern Medical School, The University of Texas Health Science Center at Houston, Houston, TX, USA.; Centro Integrativo de Biologia y Quimica Aplicada (CIBQA), Universidad Bernardo O'Higgins, Santiago, Chile., Wefel JS; Department of Neuro-Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.; Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA., Zhang C; Department of Otorhinolaryngology, Head and Neck Surgery, The University of Maryland School of Medicine, Baltimore, MD, USA., McCullough LD; Department of Neurology, McGovern Medical School, The University of Texas Health Science Center at Houston, Houston, TX, USA.; The BRAINS Research Laboratory, the Department of Neurology, University of Texas McGovern Medical School, Houston, TX, USA.; The University of Texas Graduate School of Biomedical Sciences, Houston, TX, USA., Kim N; Division of Pharmacology and Toxicology, College of Pharmacy, The University of Texas at Austin, Austin, TX, USA., Monchaud D; Institut De Chimie Moléculaire de l'Université de Bourgogne (ICMUB), Université Bourgogne Europe (UBE), Dijon, France., Jung SY; Department of Biochemistry and Molecular Biology, Baylor College of Medicine, Houston, TX, USA., Tsvetkov AS; Department of Neurology, McGovern Medical School, The University of Texas Health Science Center at Houston, Houston, TX, USA. andrey.s.tsvetkov@uth.tmc.edu.; The BRAINS Research Laboratory, the Department of Neurology, University of Texas McGovern Medical School, Houston, TX, USA. andrey.s.tsvetkov@uth.tmc.edu.; The University of Texas Graduate School of Biomedical Sciences, Houston, TX, USA. andrey.s.tsvetkov@uth.tmc.edu.
Source: Cell death & disease [Cell Death Dis] 2026 Jun 18. Date of Electronic Publication: 2026 Jun 18.
Publication Type: Journal Article
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101524092 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2041-4889 (Electronic) NLM ISO Abbreviation: Cell Death Dis Subsets: MEDLINE
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  Data: Sex-linked helicases DDX3X and DDX3Y regulate G-quadruplex-associated stress in neurons.
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  Data: <searchLink fieldCode="AU" term="%22Diaz+Escarcega+R%22">Diaz Escarcega R</searchLink>; Department of Neurology, McGovern Medical School, The University of Texas Health Science Center at Houston, Houston, TX, USA.; The BRAINS Research Laboratory, the Department of Neurology, University of Texas McGovern Medical School, Houston, TX, USA.<br /><searchLink fieldCode="AU" term="%22M+J+VK%22">M J VK</searchLink>; Department of Neurology, McGovern Medical School, The University of Texas Health Science Center at Houston, Houston, TX, USA.; The BRAINS Research Laboratory, the Department of Neurology, University of Texas McGovern Medical School, Houston, TX, USA.<br /><searchLink fieldCode="AU" term="%22Arizmendez+A%22">Arizmendez A</searchLink>; Department of Neurology, McGovern Medical School, The University of Texas Health Science Center at Houston, Houston, TX, USA.; The BRAINS Research Laboratory, the Department of Neurology, University of Texas McGovern Medical School, Houston, TX, USA.<br /><searchLink fieldCode="AU" term="%22Tan+C%22">Tan C</searchLink>; Department of Neurology, McGovern Medical School, The University of Texas Health Science Center at Houston, Houston, TX, USA.; The BRAINS Research Laboratory, the Department of Neurology, University of Texas McGovern Medical School, Houston, TX, USA.<br /><searchLink fieldCode="AU" term="%22Urayama+A%22">Urayama A</searchLink>; Department of Neurology, McGovern Medical School, The University of Texas Health Science Center at Houston, Houston, TX, USA.; The BRAINS Research Laboratory, the Department of Neurology, University of Texas McGovern Medical School, Houston, TX, USA.<br /><searchLink fieldCode="AU" term="%22Marrelli+SP%22">Marrelli SP</searchLink>; Department of Neurology, McGovern Medical School, The University of Texas Health Science Center at Houston, Houston, TX, USA.; The BRAINS Research Laboratory, the Department of Neurology, University of Texas McGovern Medical School, Houston, TX, USA.<br /><searchLink fieldCode="AU" term="%22Morales+R%22">Morales R</searchLink>; Department of Neurology, McGovern Medical School, The University of Texas Health Science Center at Houston, Houston, TX, USA.; Centro Integrativo de Biologia y Quimica Aplicada (CIBQA), Universidad Bernardo O'Higgins, Santiago, Chile.<br /><searchLink fieldCode="AU" term="%22Wefel+JS%22">Wefel JS</searchLink>; Department of Neuro-Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.; Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.<br /><searchLink fieldCode="AU" term="%22Zhang+C%22">Zhang C</searchLink>; Department of Otorhinolaryngology, Head and Neck Surgery, The University of Maryland School of Medicine, Baltimore, MD, USA.<br /><searchLink fieldCode="AU" term="%22McCullough+LD%22">McCullough LD</searchLink>; Department of Neurology, McGovern Medical School, The University of Texas Health Science Center at Houston, Houston, TX, USA.; The BRAINS Research Laboratory, the Department of Neurology, University of Texas McGovern Medical School, Houston, TX, USA.; The University of Texas Graduate School of Biomedical Sciences, Houston, TX, USA.<br /><searchLink fieldCode="AU" term="%22Kim+N%22">Kim N</searchLink>; Division of Pharmacology and Toxicology, College of Pharmacy, The University of Texas at Austin, Austin, TX, USA.<br /><searchLink fieldCode="AU" term="%22Monchaud+D%22">Monchaud D</searchLink>; Institut De Chimie Moléculaire de l'Université de Bourgogne (ICMUB), Université Bourgogne Europe (UBE), Dijon, France.<br /><searchLink fieldCode="AU" term="%22Jung+SY%22">Jung SY</searchLink>; Department of Biochemistry and Molecular Biology, Baylor College of Medicine, Houston, TX, USA.<br /><searchLink fieldCode="AU" term="%22Tsvetkov+AS%22">Tsvetkov AS</searchLink>; Department of Neurology, McGovern Medical School, The University of Texas Health Science Center at Houston, Houston, TX, USA. andrey.s.tsvetkov@uth.tmc.edu.; The BRAINS Research Laboratory, the Department of Neurology, University of Texas McGovern Medical School, Houston, TX, USA. andrey.s.tsvetkov@uth.tmc.edu.; The University of Texas Graduate School of Biomedical Sciences, Houston, TX, USA. andrey.s.tsvetkov@uth.tmc.edu.
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