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High performance of point-of-care rapid tests for advanced HIV disease diagnosis by lay providers in Malawi: Results from a prospective diagnostic accuracy study supporting decentralized advanced HIV disease screening.

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Title: High performance of point-of-care rapid tests for advanced HIV disease diagnosis by lay providers in Malawi: Results from a prospective diagnostic accuracy study supporting decentralized advanced HIV disease screening.
Authors: Thawani A; Lighthouse Trust, Lilongwe, Malawi., Rambiki E; Lighthouse Trust, Lilongwe, Malawi., Huwa J; Lighthouse Trust, Lilongwe, Malawi., Gabriel L; Lighthouse Trust, Lilongwe, Malawi., Kudzala A; Lighthouse Trust, Lilongwe, Malawi., Kiruthu-Kamamia C; Lighthouse Trust, Lilongwe, Malawi.; International Training and Education Center for Health, University of Washington, Seattle, Washington, United States of America., Bisani P; Lighthouse Trust, Lilongwe, Malawi., Buleya S; Lighthouse Trust, Lilongwe, Malawi., Ford NP; Global HIV, Hepatitis and STI Programmes, World Health Organization, Geneva, Switzerland., Johnson CC; Global HIV, Hepatitis and STI Programmes, World Health Organization, Geneva, Switzerland., Rangaraj A; Global HIV, Hepatitis and STI Programmes, World Health Organization, Geneva, Switzerland., Luo R; Global HIV, Hepatitis and STI Programmes, World Health Organization, Geneva, Switzerland., Lastrucci C; Global HIV, Hepatitis and STI Programmes, World Health Organization, Geneva, Switzerland., Msimanga B; Global HIV, Hepatitis and STI Programmes, World Health Organization, Geneva, Switzerland., Nyirenda R; Department of HIV and AIDS, Ministry of Health, Malawi., Matola BW; Department of HIV and AIDS, Ministry of Health, Malawi., Jahn A; International Training and Education Center for Health, University of Washington, Seattle, Washington, United States of America.; Department of HIV and AIDS, Ministry of Health, Malawi., Wallrauch C; Lighthouse Trust, Lilongwe, Malawi.; LMU University Hospital Munich, Division of Infectious Diseases and Tropical Medicine, Munich, Germany., Burke R; London School of Hygiene & Tropical Medicine, United Kingdom of Great Britain and Northern Ireland., Heller T; Lighthouse Trust, Lilongwe, Malawi.; International Training and Education Center for Health, University of Washington, Seattle, Washington, United States of America.
Source: PloS one [PLoS One] 2026 Jun 18; Vol. 21 (6), pp. e0340955. Date of Electronic Publication: 2026 Jun 18 (Print Publication: 2026).
Publication Type: Journal Article
Journal Info: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet ISSN: 1932-6203 (Electronic) Linking ISSN: 19326203 NLM ISO Abbreviation: PLoS One Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: High performance of point-of-care rapid tests for advanced HIV disease diagnosis by lay providers in Malawi: Results from a prospective diagnostic accuracy study supporting decentralized advanced HIV disease screening.
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  Data: <searchLink fieldCode="AU" term="%22Thawani+A%22">Thawani A</searchLink>; Lighthouse Trust, Lilongwe, Malawi.<br /><searchLink fieldCode="AU" term="%22Rambiki+E%22">Rambiki E</searchLink>; Lighthouse Trust, Lilongwe, Malawi.<br /><searchLink fieldCode="AU" term="%22Huwa+J%22">Huwa J</searchLink>; Lighthouse Trust, Lilongwe, Malawi.<br /><searchLink fieldCode="AU" term="%22Gabriel+L%22">Gabriel L</searchLink>; Lighthouse Trust, Lilongwe, Malawi.<br /><searchLink fieldCode="AU" term="%22Kudzala+A%22">Kudzala A</searchLink>; Lighthouse Trust, Lilongwe, Malawi.<br /><searchLink fieldCode="AU" term="%22Kiruthu-Kamamia+C%22">Kiruthu-Kamamia C</searchLink>; Lighthouse Trust, Lilongwe, Malawi.; International Training and Education Center for Health, University of Washington, Seattle, Washington, United States of America.<br /><searchLink fieldCode="AU" term="%22Bisani+P%22">Bisani P</searchLink>; Lighthouse Trust, Lilongwe, Malawi.<br /><searchLink fieldCode="AU" term="%22Buleya+S%22">Buleya S</searchLink>; Lighthouse Trust, Lilongwe, Malawi.<br /><searchLink fieldCode="AU" term="%22Ford+NP%22">Ford NP</searchLink>; Global HIV, Hepatitis and STI Programmes, World Health Organization, Geneva, Switzerland.<br /><searchLink fieldCode="AU" term="%22Johnson+CC%22">Johnson CC</searchLink>; Global HIV, Hepatitis and STI Programmes, World Health Organization, Geneva, Switzerland.<br /><searchLink fieldCode="AU" term="%22Rangaraj+A%22">Rangaraj A</searchLink>; Global HIV, Hepatitis and STI Programmes, World Health Organization, Geneva, Switzerland.<br /><searchLink fieldCode="AU" term="%22Luo+R%22">Luo R</searchLink>; Global HIV, Hepatitis and STI Programmes, World Health Organization, Geneva, Switzerland.<br /><searchLink fieldCode="AU" term="%22Lastrucci+C%22">Lastrucci C</searchLink>; Global HIV, Hepatitis and STI Programmes, World Health Organization, Geneva, Switzerland.<br /><searchLink fieldCode="AU" term="%22Msimanga+B%22">Msimanga B</searchLink>; Global HIV, Hepatitis and STI Programmes, World Health Organization, Geneva, Switzerland.<br /><searchLink fieldCode="AU" term="%22Nyirenda+R%22">Nyirenda R</searchLink>; Department of HIV and AIDS, Ministry of Health, Malawi.<br /><searchLink fieldCode="AU" term="%22Matola+BW%22">Matola BW</searchLink>; Department of HIV and AIDS, Ministry of Health, Malawi.<br /><searchLink fieldCode="AU" term="%22Jahn+A%22">Jahn A</searchLink>; International Training and Education Center for Health, University of Washington, Seattle, Washington, United States of America.; Department of HIV and AIDS, Ministry of Health, Malawi.<br /><searchLink fieldCode="AU" term="%22Wallrauch+C%22">Wallrauch C</searchLink>; Lighthouse Trust, Lilongwe, Malawi.; LMU University Hospital Munich, Division of Infectious Diseases and Tropical Medicine, Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Burke+R%22">Burke R</searchLink>; London School of Hygiene & Tropical Medicine, United Kingdom of Great Britain and Northern Ireland.<br /><searchLink fieldCode="AU" term="%22Heller+T%22">Heller T</searchLink>; Lighthouse Trust, Lilongwe, Malawi.; International Training and Education Center for Health, University of Washington, Seattle, Washington, United States of America.
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