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Lamprey 3D single-cell transcriptomics reveals ancestral and specialized features of the vertebrate brain.

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Title: Lamprey 3D single-cell transcriptomics reveals ancestral and specialized features of the vertebrate brain.
Authors: Wu H; State Key Laboratory of Genetic Evolution and Animal Model, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming, China.; College of Life Sciences, University of Chinese Academy of Sciences, Beijing, China., Chen D; State Key Laboratory of Genome and Multi-omics Technologies, BGI Research, Hangzhou, China., Li J; College of Life Science, Liaoning Normal University, Dalian, China., Zhou T; College of Life Sciences, University of Chinese Academy of Sciences, Beijing, China.; BGI Research, Hangzhou, China.; Key Laboratory of Spatial Omics of Zhejiang Province, BGI Research, Hangzhou, China., Zhuang Z; BGI Research, Hangzhou, China.; Key Laboratory of Spatial Omics of Zhejiang Province, BGI Research, Hangzhou, China.; BGI Research, Shenzhen, China., Niu Z; College of Life Sciences, University of Chinese Academy of Sciences, Beijing, China.; BGI Research, Hangzhou, China.; Key Laboratory of Spatial Omics of Zhejiang Province, BGI Research, Hangzhou, China., Du Z; College of Life Science, Liaoning Normal University, Dalian, China.; Lamprey Research Center, Liaoning Normal University, Dalian, China., Chen Y; State Key Laboratory of Genetic Evolution and Animal Model, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming, China.; College of Life Sciences, University of Chinese Academy of Sciences, Beijing, China., Chuan S; College of Life Science, Liaoning Normal University, Dalian, China.; Lamprey Research Center, Liaoning Normal University, Dalian, China., Xu C; BGI Research, Sanya, China., Liao X; BGI Research, Shenzhen, China., Meng X; State Key Laboratory of Genetic Evolution and Animal Model, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming, China., Lu J; College of Life Science, Liaoning Normal University, Dalian, China.; Lamprey Research Center, Liaoning Normal University, Dalian, China., Cui W; College of Life Science, Liaoning Normal University, Dalian, China.; Lamprey Research Center, Liaoning Normal University, Dalian, China., Lin Y; College of Life Sciences, University of Chinese Academy of Sciences, Beijing, China.; BGI Research, Hangzhou, China.; Key Laboratory of Spatial Omics of Zhejiang Province, BGI Research, Hangzhou, China., Huang F; College of Life Sciences, University of Chinese Academy of Sciences, Beijing, China.; BGI Research, Hangzhou, China.; Key Laboratory of Spatial Omics of Zhejiang Province, BGI Research, Hangzhou, China., Liao K; College of Life Sciences, University of Chinese Academy of Sciences, Beijing, China.; BGI Research, Hangzhou, China.; Key Laboratory of Spatial Omics of Zhejiang Province, BGI Research, Hangzhou, China., Liu Y; State Key Laboratory of Genetic Evolution and Animal Model, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming, China., Yang T; BGI Research, Shenzhen, China.; Guangdong Provincial Genomics Data Center, BGl Research, Shenzhen, China., Chen J; BGI Research, Shenzhen, China.; Guangdong Provincial Genomics Data Center, BGl Research, Shenzhen, China., Wang H; College of Biomedicine and Health, College of Life Science and Technology, Huazhong Agricultural University, Wuhan, China., Dong Z; College of Biomedicine and Health, College of Life Science and Technology, Huazhong Agricultural University, Wuhan, China., Liu L; BGI Research, Hangzhou, China., Fang X; BGI Research, Hangzhou, China., Xu X; BGI Research, Hangzhou, China.; BGI Research, Shenzhen, China., Li Q; College of Life Science, Liaoning Normal University, Dalian, China.; Lamprey Research Center, Liaoning Normal University, Dalian, China., Pang Y; College of Life Science, Liaoning Normal University, Dalian, China.; Lamprey Research Center, Liaoning Normal University, Dalian, China., Liu S; BGI Research, Hangzhou, China.; Key Laboratory of Spatial Omics of Zhejiang Province, BGI Research, Hangzhou, China.; BGI Research, Shenzhen, China., Su B; State Key Laboratory of Genetic Evolution and Animal Model, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming, China.; Center for Excellence in Animal Evolution and Genetics, Chinese Academy of Sciences, Kunming, China.
Source: Science (New York, N.Y.) [Science] 2026 Jun 18; Vol. 392 (6804), pp. eaea2535. Date of Electronic Publication: 2026 Jun 18.
Publication Type: Journal Article
Journal Info: Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 0404511 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1095-9203 (Electronic) Linking ISSN: 00368075 NLM ISO Abbreviation: Science Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:1095-9203
DOI:10.1126/science.aea2535