Robustness and fragility of evidence supporting systemic thrombolysis in acute pulmonary embolism.

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Title: Robustness and fragility of evidence supporting systemic thrombolysis in acute pulmonary embolism.
Authors: Zuin M; Department of Translational Medicine, University of Ferrara, Via Luigi Borsari 46, Ferrara, 44100, Italy. zuinml@yahoo.it.; Department of Cardio-Thoraco-Vascular Sciences and Public Health, University of Padova, Padua, Italy. zuinml@yahoo.it.; PhD Program in Translation Specialistic Medicine 'G.B. Morgagni', Curriculum Cardiovascular Sciences University of Padua, Padua, Italy. zuinml@yahoo.it.; Department of Cardiology, Madre Teresa Di Calcutta Hospital, AULSS 6 Ospedali Riuniti Padova Sud, Monselice, Italy. zuinml@yahoo.it., Ageno W; Department of Medicine, University of Padua, Padua, Italy., Vedovati MC; Internal, Vascular and Emergency Medicine - Stroke Unit, University of Perugia, Perugia, Italy., Chopard R; Department of Cardiology, Centre Hospitalier Universitaire de Besançon, Besançon, France.; SINERGIES Laboratory, University Marie and Louis Pasteur, Besançon, France.; F-CRIN, INNOVTE Network, Saint-Étienne, France., Goldhaber SZ; Thrombosis Research Group, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.; Division of Cardiovascular Medicine, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA., Simioni P; Department of Medicine, General Medicine and Thrombotic and Hemorrhagic Diseases Unit, University Hospital of Padova, Padova, Italy.
Source: Journal of thrombosis and thrombolysis [J Thromb Thrombolysis] 2026 Jun 18. Date of Electronic Publication: 2026 Jun 18.
Publication Type: Journal Article
Journal Info: Publisher: Kluwer Academic Publishers Country of Publication: Netherlands NLM ID: 9502018 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1573-742X (Electronic) Linking ISSN: 09295305 NLM ISO Abbreviation: J Thromb Thrombolysis Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1573-742X
DOI:10.1007/s11239-026-03344-x