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Intraoperative Zoledronic Acid for Arthroscopic Rotator Cuff Repair Results in Distinct Circulating Micro-RNA Profiles Indicating Improved Tendon-to-Bone Healing.

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Title: Intraoperative Zoledronic Acid for Arthroscopic Rotator Cuff Repair Results in Distinct Circulating Micro-RNA Profiles Indicating Improved Tendon-to-Bone Healing.
Authors: Schanda JE; Department of Orthopedics and Trauma Surgery, AUVA Trauma Center Vienna-Meidling, Vienna, Austria.; Ludwig Boltzmann Institute for Traumatology - The Research Center in Cooperation with AUVA, Vienna, Austria.; Austrian Cluster for Tissue Regeneration, Vienna, Austria., Hackl M; TAmiRNA GmbH, Vienna, Austria., Bischl R; TAmiRNA GmbH, Vienna, Austria., Ullrich R; Department of Anesthesiology, AUVA Trauma Center Vienna-Meidling, Vienna, Austria., Boesmueller S; Department of Orthopedics and Trauma Surgery, AUVA Trauma Center Vienna-Meidling, Vienna, Austria., Mittermayr R; Department of Orthopedics and Trauma Surgery, AUVA Trauma Center Vienna-Meidling, Vienna, Austria.; Ludwig Boltzmann Institute for Traumatology - The Research Center in Cooperation with AUVA, Vienna, Austria.; Austrian Cluster for Tissue Regeneration, Vienna, Austria., Redl H; Ludwig Boltzmann Institute for Traumatology - The Research Center in Cooperation with AUVA, Vienna, Austria.; Austrian Cluster for Tissue Regeneration, Vienna, Austria., Grillari J; Ludwig Boltzmann Institute for Traumatology - The Research Center in Cooperation with AUVA, Vienna, Austria.; Austrian Cluster for Tissue Regeneration, Vienna, Austria.; BOKU University, Institute of Molecular Biotechnology, Vienna, Austria., Fialka C; Department of Orthopedics and Trauma Surgery, AUVA Trauma Center Vienna-Meidling, Vienna, Austria.; Sigmund Freud University, Medical Faculty, Center for the Musculoskeletal System, Vienna, Austria.
Source: The American journal of sports medicine [Am J Sports Med] 2026 Aug; Vol. 54 (10), pp. 2516-2526. Date of Electronic Publication: 2026 Jun 18.
Publication Type: Journal Article; Randomized Controlled Trial; Clinical Trial, Phase II
Journal Info: Publisher: Sage Publications Country of Publication: United States NLM ID: 7609541 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1552-3365 (Electronic) Linking ISSN: 03635465 NLM ISO Abbreviation: Am J Sports Med Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Intraoperative Zoledronic Acid for Arthroscopic Rotator Cuff Repair Results in Distinct Circulating Micro-RNA Profiles Indicating Improved Tendon-to-Bone Healing.
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  Data: <searchLink fieldCode="AU" term="%22Schanda+JE%22">Schanda JE</searchLink>; Department of Orthopedics and Trauma Surgery, AUVA Trauma Center Vienna-Meidling, Vienna, Austria.; Ludwig Boltzmann Institute for Traumatology - The Research Center in Cooperation with AUVA, Vienna, Austria.; Austrian Cluster for Tissue Regeneration, Vienna, Austria.<br /><searchLink fieldCode="AU" term="%22Hackl+M%22">Hackl M</searchLink>; TAmiRNA GmbH, Vienna, Austria.<br /><searchLink fieldCode="AU" term="%22Bischl+R%22">Bischl R</searchLink>; TAmiRNA GmbH, Vienna, Austria.<br /><searchLink fieldCode="AU" term="%22Ullrich+R%22">Ullrich R</searchLink>; Department of Anesthesiology, AUVA Trauma Center Vienna-Meidling, Vienna, Austria.<br /><searchLink fieldCode="AU" term="%22Boesmueller+S%22">Boesmueller S</searchLink>; Department of Orthopedics and Trauma Surgery, AUVA Trauma Center Vienna-Meidling, Vienna, Austria.<br /><searchLink fieldCode="AU" term="%22Mittermayr+R%22">Mittermayr R</searchLink>; Department of Orthopedics and Trauma Surgery, AUVA Trauma Center Vienna-Meidling, Vienna, Austria.; Ludwig Boltzmann Institute for Traumatology - The Research Center in Cooperation with AUVA, Vienna, Austria.; Austrian Cluster for Tissue Regeneration, Vienna, Austria.<br /><searchLink fieldCode="AU" term="%22Redl+H%22">Redl H</searchLink>; Ludwig Boltzmann Institute for Traumatology - The Research Center in Cooperation with AUVA, Vienna, Austria.; Austrian Cluster for Tissue Regeneration, Vienna, Austria.<br /><searchLink fieldCode="AU" term="%22Grillari+J%22">Grillari J</searchLink>; Ludwig Boltzmann Institute for Traumatology - The Research Center in Cooperation with AUVA, Vienna, Austria.; Austrian Cluster for Tissue Regeneration, Vienna, Austria.; BOKU University, Institute of Molecular Biotechnology, Vienna, Austria.<br /><searchLink fieldCode="AU" term="%22Fialka+C%22">Fialka C</searchLink>; Department of Orthopedics and Trauma Surgery, AUVA Trauma Center Vienna-Meidling, Vienna, Austria.; Sigmund Freud University, Medical Faculty, Center for the Musculoskeletal System, Vienna, Austria.
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  Data: <searchLink fieldCode="JN" term="%227609541%22">The American journal of sports medicine</searchLink> [Am J Sports Med] 2026 Aug; Vol. 54 (10), pp. 2516-2526. <i>Date of Electronic Publication: </i>2026 Jun 18.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Sage+Publications%22">Sage Publications </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>7609541 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1552-3365 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2203635465%22">03635465 </searchLink><i>NLM ISO Abbreviation: </i>Am J Sports Med <i>Subsets: </i>MEDLINE
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              Text: 2026 Aug
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