View in EDS HTML Full Text PDF Full Text

Complementary efficacy of CD127-directed immunotherapy with lusvertikimab and ABL-targeting tyrosine kinase inhibitors in preclinical ABL-class-fusion-positive B-ALL.

Saved in:
Bibliographic Details
Title: Complementary efficacy of CD127-directed immunotherapy with lusvertikimab and ABL-targeting tyrosine kinase inhibitors in preclinical ABL-class-fusion-positive B-ALL.
Authors: Pinkle D; Department of Pediatrics I, ALL-BFM Study Group Christian-Albrechts University Kiel and University Medical Center Schleswig-Holstein Kiel Germany.; University Cancer Center Schleswig-Holstein (UCCSH) University Medical Center Schleswig-Holstein Kiel Germany., Cornils M; Department of Pediatrics I, ALL-BFM Study Group Christian-Albrechts University Kiel and University Medical Center Schleswig-Holstein Kiel Germany.; University Cancer Center Schleswig-Holstein (UCCSH) University Medical Center Schleswig-Holstein Kiel Germany., Dietterle A; Department of Pediatrics I, ALL-BFM Study Group Christian-Albrechts University Kiel and University Medical Center Schleswig-Holstein Kiel Germany.; University Cancer Center Schleswig-Holstein (UCCSH) University Medical Center Schleswig-Holstein Kiel Germany., Laqua A; University Cancer Center Schleswig-Holstein (UCCSH) University Medical Center Schleswig-Holstein Kiel Germany.; Medical Department II Hematology and Oncology University Medical Center Schleswig-Holstein Kiel Germany., Kurschies M; Department of Pediatrics I, ALL-BFM Study Group Christian-Albrechts University Kiel and University Medical Center Schleswig-Holstein Kiel Germany.; University Cancer Center Schleswig-Holstein (UCCSH) University Medical Center Schleswig-Holstein Kiel Germany., Heymann J; Department of Pediatrics I, ALL-BFM Study Group Christian-Albrechts University Kiel and University Medical Center Schleswig-Holstein Kiel Germany.; University Cancer Center Schleswig-Holstein (UCCSH) University Medical Center Schleswig-Holstein Kiel Germany., Funke E; Department of Pediatrics I, ALL-BFM Study Group Christian-Albrechts University Kiel and University Medical Center Schleswig-Holstein Kiel Germany.; University Cancer Center Schleswig-Holstein (UCCSH) University Medical Center Schleswig-Holstein Kiel Germany., Fanter P; Department of Pediatrics I, ALL-BFM Study Group Christian-Albrechts University Kiel and University Medical Center Schleswig-Holstein Kiel Germany.; University Cancer Center Schleswig-Holstein (UCCSH) University Medical Center Schleswig-Holstein Kiel Germany., Gupta DD; University Cancer Center Schleswig-Holstein (UCCSH) University Medical Center Schleswig-Holstein Kiel Germany.; Medical Department II Hematology and Oncology University Medical Center Schleswig-Holstein Kiel Germany.; Clinical Research Unit CATCH ALL KFO Kiel Germany., Reimer C; Department of Pediatrics I, ALL-BFM Study Group Christian-Albrechts University Kiel and University Medical Center Schleswig-Holstein Kiel Germany.; University Cancer Center Schleswig-Holstein (UCCSH) University Medical Center Schleswig-Holstein Kiel Germany., Mahachi DT; Department of Pediatrics I, ALL-BFM Study Group Christian-Albrechts University Kiel and University Medical Center Schleswig-Holstein Kiel Germany.; University Cancer Center Schleswig-Holstein (UCCSH) University Medical Center Schleswig-Holstein Kiel Germany., Gehlert CL; University Cancer Center Schleswig-Holstein (UCCSH) University Medical Center Schleswig-Holstein Kiel Germany.; Medical Department II Hematology and Oncology University Medical Center Schleswig-Holstein Kiel Germany., Winterberg D; University Cancer Center Schleswig-Holstein (UCCSH) University Medical Center Schleswig-Holstein Kiel Germany.; Medical Department II Hematology and Oncology University Medical Center Schleswig-Holstein Kiel Germany.; Clinical Research Unit CATCH ALL KFO Kiel Germany., Vossen-Gajcy M; Department of Pediatrics I, ALL-BFM Study Group Christian-Albrechts University Kiel and University Medical Center Schleswig-Holstein Kiel Germany.; University Cancer Center Schleswig-Holstein (UCCSH) University Medical Center Schleswig-Holstein Kiel Germany., Müller X; Department of Pediatrics I, ALL-BFM Study Group Christian-Albrechts University Kiel and University Medical Center Schleswig-Holstein Kiel Germany.; University Cancer Center Schleswig-Holstein (UCCSH) University Medical Center Schleswig-Holstein Kiel Germany.; Clinical Research Unit CATCH ALL KFO Kiel Germany., Balow G; Department of Pediatrics I, ALL-BFM Study Group Christian-Albrechts University Kiel and University Medical Center Schleswig-Holstein Kiel Germany.; University Cancer Center Schleswig-Holstein (UCCSH) University Medical Center Schleswig-Holstein Kiel Germany., Iben K; University Cancer Center Schleswig-Holstein (UCCSH) University Medical Center Schleswig-Holstein Kiel Germany.; Medical Department II Hematology and Oncology University Medical Center Schleswig-Holstein Kiel Germany.; Clinical Research Unit CATCH ALL KFO Kiel Germany., Barz M; University Cancer Center Schleswig-Holstein (UCCSH) University Medical Center Schleswig-Holstein Kiel Germany.; Medical Department II Hematology and Oncology University Medical Center Schleswig-Holstein Kiel Germany.; Clinical Research Unit CATCH ALL KFO Kiel Germany., Bastian L; University Cancer Center Schleswig-Holstein (UCCSH) University Medical Center Schleswig-Holstein Kiel Germany.; Medical Department II Hematology and Oncology University Medical Center Schleswig-Holstein Kiel Germany.; Clinical Research Unit CATCH ALL KFO Kiel Germany., Baldus C; University Cancer Center Schleswig-Holstein (UCCSH) University Medical Center Schleswig-Holstein Kiel Germany.; Medical Department II Hematology and Oncology University Medical Center Schleswig-Holstein Kiel Germany.; Clinical Research Unit CATCH ALL KFO Kiel Germany., Kowol M; University Cancer Center Schleswig-Holstein (UCCSH) University Medical Center Schleswig-Holstein Kiel Germany.; Medical Department II Hematology and Oncology University Medical Center Schleswig-Holstein Kiel Germany., Kikvadze S; Department of Pediatric Hematology and Oncology University Hospital Dresden Dresden Germany.; National Center for Tumor Diseases (NCT/UCC) Dresden Dresden Germany., Wurm AA; Department of Pediatric Hematology and Oncology University Hospital Dresden Dresden Germany.; National Center for Tumor Diseases (NCT/UCC) Dresden Dresden Germany.; German Cancer Consortium (DKTK) Partner Site Dresden Dresden Germany., Logvinova E; Department of Pediatric Hematology and Oncology University Hospital Dresden Dresden Germany.; National Center for Tumor Diseases (NCT/UCC) Dresden Dresden Germany., Vokuhl C; Section of Pediatric Pathology, Department of Pathology University Hospital Bonn Bonn Germany., Schmid JP; Research Unit Apoptosis in Hematopoietic Stem Cells Helmholtz Center Munich Munich Germany., Jeremias I; Research Unit Apoptosis in Hematopoietic Stem Cells Helmholtz Center Munich Munich Germany., Klausz K; University Cancer Center Schleswig-Holstein (UCCSH) University Medical Center Schleswig-Holstein Kiel Germany.; Medical Department II Hematology and Oncology University Medical Center Schleswig-Holstein Kiel Germany.; Clinical Research Unit CATCH ALL KFO Kiel Germany., Peipp M; University Cancer Center Schleswig-Holstein (UCCSH) University Medical Center Schleswig-Holstein Kiel Germany.; Medical Department II Hematology and Oncology University Medical Center Schleswig-Holstein Kiel Germany.; Clinical Research Unit CATCH ALL KFO Kiel Germany., Schrappe M; Department of Pediatrics I, ALL-BFM Study Group Christian-Albrechts University Kiel and University Medical Center Schleswig-Holstein Kiel Germany.; University Cancer Center Schleswig-Holstein (UCCSH) University Medical Center Schleswig-Holstein Kiel Germany.; Clinical Research Unit CATCH ALL KFO Kiel Germany., Baccelli I; OSE Immunotherapeutics Nantes France., Poirier N; OSE Immunotherapeutics Nantes France., Brüggemann M; University Cancer Center Schleswig-Holstein (UCCSH) University Medical Center Schleswig-Holstein Kiel Germany.; Medical Department II Hematology and Oncology University Medical Center Schleswig-Holstein Kiel Germany.; Clinical Research Unit CATCH ALL KFO Kiel Germany., Cario G; Department of Pediatrics I, ALL-BFM Study Group Christian-Albrechts University Kiel and University Medical Center Schleswig-Holstein Kiel Germany.; University Cancer Center Schleswig-Holstein (UCCSH) University Medical Center Schleswig-Holstein Kiel Germany.; Clinical Research Unit CATCH ALL KFO Kiel Germany., Schewe DM; Clinical Research Unit CATCH ALL KFO Kiel Germany.; Department of Pediatric Hematology and Oncology University Hospital Dresden Dresden Germany.; National Center for Tumor Diseases (NCT/UCC) Dresden Dresden Germany., Lenk L; Department of Pediatrics I, ALL-BFM Study Group Christian-Albrechts University Kiel and University Medical Center Schleswig-Holstein Kiel Germany.; University Cancer Center Schleswig-Holstein (UCCSH) University Medical Center Schleswig-Holstein Kiel Germany.; Clinical Research Unit CATCH ALL KFO Kiel Germany.
Source: HemaSphere [Hemasphere] 2026 Jun 17; Vol. 10 (6), pp. e70407. Date of Electronic Publication: 2026 Jun 17 (Print Publication: 2026).
Publication Type: Letter
Journal Info: Publisher: Wiley Country of Publication: United States NLM ID: 101740619 Publication Model: eCollection Cited Medium: Internet ISSN: 2572-9241 (Electronic) Linking ISSN: 25729241 NLM ISO Abbreviation: Hemasphere Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
Full text is not displayed to guests.
Description
ISSN:2572-9241
DOI:10.1002/hem3.70407