Integrative plasma proteomics and myeloid- interferon profiling reveal an AI-validated vascular- endothelial stress signature distinguishing SLE flare from remission in an Indian cohort a discovery - phase study.

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Title: Integrative plasma proteomics and myeloid- interferon profiling reveal an AI-validated vascular- endothelial stress signature distinguishing SLE flare from remission in an Indian cohort a discovery - phase study.
Authors: Karmakar A; Department of General Medicine, Kasturba Medical College, Manipal Academy of Higher Education, Manipal, India.; Department of Biochemistry, All India Institute of Medical Sciences, New Delhi, India., Mishra S; Department of Gastroenterology and Hepatology, Kasturba Medical College, Manipal Academy of Higher Education, Manipal, India., Kumar U; Department of Rheumatology, All India Institute of Medical Sciences, New Delhi, India., Kamath R; Department of General Medicine, Kasturba Medical College, Manipal Academy of Higher Education, Manipal, India., Ravindran V; Department of General Medicine, Kasturba Medical College, Manipal Academy of Higher Education, Manipal, India.; Department of Rheumatology, Centre for Rheumatology, Kozhikode, Kerala, India., Suryakanth VB; Department of Biochemistry, Kasturba Medical College, Manipal Academy of Higher Education, Manipal, India., Prabhu S; Department of Dermatology, Kasturba Medical College, Manipal Academy Higher Education, Manipal, India., Nagaraju SP; Department of Nephrology, Kasturba Medical College, Manipal Academy of Higher Education, Manipal, India., Prabhu MM; Department of General Medicine, Kasturba Medical College, Manipal Academy of Higher Education, Manipal, India., Karmakar S; Department of Biochemistry, All India Institute of Medical Sciences, New Delhi, India.
Source: Frontiers in immunology [Front Immunol] 2026 Jun 03; Vol. 17, pp. 1819049. Date of Electronic Publication: 2026 Jun 03 (Print Publication: 2026).
Publication Type: Journal Article
Journal Info: Publisher: Frontiers Research Foundation] Country of Publication: Switzerland NLM ID: 101560960 Publication Model: eCollection Cited Medium: Internet ISSN: 1664-3224 (Electronic) Linking ISSN: 16643224 NLM ISO Abbreviation: Front Immunol Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:1664-3224
DOI:10.3389/fimmu.2026.1819049