Preoperative malnutrition is associated with suppressed intratumoral T cell function and distinct tumor-associated microbiota in colorectal cancer: a prospective pilot study.

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Title: Preoperative malnutrition is associated with suppressed intratumoral T cell function and distinct tumor-associated microbiota in colorectal cancer: a prospective pilot study.
Authors: Perillo F; Department of Biotechnology and Biosciences, University of Milan-Bicocca, Milan, Italy., Mascaretti F; Gastroenterology and Endoscopy Unit, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy., Maragno P; Gastroenterology and Endoscopy Unit, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy., Amoroso C; Gastroenterology and Endoscopy Unit, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy., Oriani E; Department of Biotechnology and Biosciences, University of Milan-Bicocca, Milan, Italy., Baeri A; Department of Biotechnology and Biosciences, University of Milan-Bicocca, Milan, Italy., Pinco P; Department of Biotechnology and Biosciences, University of Milan-Bicocca, Milan, Italy., Pozzi L; Gastroenterology and Endoscopy Unit, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy., Baldari L; Department of General and Minimally Invasive Surgery, IRCCS Ca' Granda, Hospital Maggiore Policlinico, Milan, Italy., Caprioli F; Gastroenterology and Endoscopy Unit, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy.; Department of Pathophysiology and Transplantation, University of Milan, Milan, Italy., Ghidini M; Medical Oncology, IRCCS Ca' Granda, Ospedale Maggiore Policlinico, Milan, Italy., Strati F; Gastroenterology and Endoscopy Unit, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy., Facciotti F; Department of Biotechnology and Biosciences, University of Milan-Bicocca, Milan, Italy.
Source: Frontiers in nutrition [Front Nutr] 2026 May 28; Vol. 13, pp. 1802354. Date of Electronic Publication: 2026 May 28 (Print Publication: 2026).
Publication Type: Journal Article
Journal Info: Publisher: Frontiers Media S. A Country of Publication: Switzerland NLM ID: 101642264 Publication Model: eCollection Cited Medium: Print ISSN: 2296-861X (Print) Linking ISSN: 2296861X NLM ISO Abbreviation: Front Nutr Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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ISSN:2296-861X
DOI:10.3389/fnut.2026.1802354