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Preoperative malnutrition is associated with suppressed intratumoral T cell function and distinct tumor-associated microbiota in colorectal cancer: a prospective pilot study.

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Title: Preoperative malnutrition is associated with suppressed intratumoral T cell function and distinct tumor-associated microbiota in colorectal cancer: a prospective pilot study.
Authors: Perillo F; Department of Biotechnology and Biosciences, University of Milan-Bicocca, Milan, Italy., Mascaretti F; Gastroenterology and Endoscopy Unit, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy., Maragno P; Gastroenterology and Endoscopy Unit, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy., Amoroso C; Gastroenterology and Endoscopy Unit, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy., Oriani E; Department of Biotechnology and Biosciences, University of Milan-Bicocca, Milan, Italy., Baeri A; Department of Biotechnology and Biosciences, University of Milan-Bicocca, Milan, Italy., Pinco P; Department of Biotechnology and Biosciences, University of Milan-Bicocca, Milan, Italy., Pozzi L; Gastroenterology and Endoscopy Unit, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy., Baldari L; Department of General and Minimally Invasive Surgery, IRCCS Ca' Granda, Hospital Maggiore Policlinico, Milan, Italy., Caprioli F; Gastroenterology and Endoscopy Unit, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy.; Department of Pathophysiology and Transplantation, University of Milan, Milan, Italy., Ghidini M; Medical Oncology, IRCCS Ca' Granda, Ospedale Maggiore Policlinico, Milan, Italy., Strati F; Gastroenterology and Endoscopy Unit, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy., Facciotti F; Department of Biotechnology and Biosciences, University of Milan-Bicocca, Milan, Italy.
Source: Frontiers in nutrition [Front Nutr] 2026 May 28; Vol. 13, pp. 1802354. Date of Electronic Publication: 2026 May 28 (Print Publication: 2026).
Publication Type: Journal Article
Journal Info: Publisher: Frontiers Media S. A Country of Publication: Switzerland NLM ID: 101642264 Publication Model: eCollection Cited Medium: Print ISSN: 2296-861X (Print) Linking ISSN: 2296861X NLM ISO Abbreviation: Front Nutr Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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  Data: Preoperative malnutrition is associated with suppressed intratumoral T cell function and distinct tumor-associated microbiota in colorectal cancer: a prospective pilot study.
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  Data: <searchLink fieldCode="AU" term="%22Perillo+F%22">Perillo F</searchLink>; Department of Biotechnology and Biosciences, University of Milan-Bicocca, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Mascaretti+F%22">Mascaretti F</searchLink>; Gastroenterology and Endoscopy Unit, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Maragno+P%22">Maragno P</searchLink>; Gastroenterology and Endoscopy Unit, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Amoroso+C%22">Amoroso C</searchLink>; Gastroenterology and Endoscopy Unit, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Oriani+E%22">Oriani E</searchLink>; Department of Biotechnology and Biosciences, University of Milan-Bicocca, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Baeri+A%22">Baeri A</searchLink>; Department of Biotechnology and Biosciences, University of Milan-Bicocca, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Pinco+P%22">Pinco P</searchLink>; Department of Biotechnology and Biosciences, University of Milan-Bicocca, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Pozzi+L%22">Pozzi L</searchLink>; Gastroenterology and Endoscopy Unit, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Baldari+L%22">Baldari L</searchLink>; Department of General and Minimally Invasive Surgery, IRCCS Ca' Granda, Hospital Maggiore Policlinico, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Caprioli+F%22">Caprioli F</searchLink>; Gastroenterology and Endoscopy Unit, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy.; Department of Pathophysiology and Transplantation, University of Milan, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Ghidini+M%22">Ghidini M</searchLink>; Medical Oncology, IRCCS Ca' Granda, Ospedale Maggiore Policlinico, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Strati+F%22">Strati F</searchLink>; Gastroenterology and Endoscopy Unit, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Facciotti+F%22">Facciotti F</searchLink>; Department of Biotechnology and Biosciences, University of Milan-Bicocca, Milan, Italy.
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