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Osteoarthritis pain inversely correlates with histidine and glutamine following CSF and serum profiling.

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Title: Osteoarthritis pain inversely correlates with histidine and glutamine following CSF and serum profiling.
Authors: Dunstan IK; Department of Pharmacology, Medical Sciences Division, University of Oxford, Mansfield Road, Oxford, OX1 3QT, UK.; Department of Chemistry, Mathematical, Physical & Life Sciences Division, University of Oxford, Oxford, UK., Rasmussen LJH; Department of Clinical Research, Copenhagen University Hospital, Hvidovre, Denmark., Probert F; Department of Chemistry, Mathematical, Physical & Life Sciences Division, University of Oxford, Oxford, UK., Olsen DA; Department of Biochemistry and Immunology, Lillebaelt Hospital, University Hospital of Southern Denmark, Vejle, Denmark., Madsen JS; Department of Biochemistry and Immunology, Lillebaelt Hospital, University Hospital of Southern Denmark, Vejle, Denmark.; Department of Regional Health Research, Faculty of Health Sciences, University of Southern Denmark, Odense, Denmark., Eugen-Olsen J; Department of Clinical Research, Copenhagen University Hospital, Hvidovre, Denmark.; Department of Cardiology, Copenhagen University Hospital-Herlev and Gentofte Hospital, Herlev, Denmark., Enggaard TP; Department of Anaesthesia, Multidiciplinary Pain Center, Copenhagen University Hospital, Copenhagen, Denmark., Varnum C; Department of Regional Health Research, Faculty of Health Sciences, University of Southern Denmark, Odense, Denmark.; Department of Orthopedic Surgery, Lillebaelt Hospital, University Hospital of Southern Denmark, Vejle, Denmark., Lambertsen KL; Department of Neurology, Odense University Hospital, Odense, Denmark.; Department of Neurobiology Research, Institute of Molecular Medicine, University of Southern Denmark, Odense, Denmark.; BRIDGE, Brain Research-Inter Disciplinary Guided Excellence, Department of Clinical Research, University of Southern Denmark, Odense, Denmark., Anthony DC; Department of Pharmacology, Medical Sciences Division, University of Oxford, Mansfield Road, Oxford, OX1 3QT, UK. daniel.anthony@pharm.ox.ac.uk., Blichfeldt-Eckhardt MR; Department of Regional Health Research, Faculty of Health Sciences, University of Southern Denmark, Odense, Denmark.; Department of Anaesthesia, Lillebaelt Hospital, University Hospital of Southern Denmark, Vejle, Denmark.
Source: Arthritis research & therapy [Arthritis Res Ther] 2026 Jun 19. Date of Electronic Publication: 2026 Jun 19.
Publication Type: Journal Article
Journal Info: Publisher: BioMed Central Country of Publication: England NLM ID: 101154438 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1478-6362 (Electronic) Linking ISSN: 14786354 NLM ISO Abbreviation: Arthritis Res Ther Subsets: MEDLINE
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  Data: Osteoarthritis pain inversely correlates with histidine and glutamine following CSF and serum profiling.
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  Data: <searchLink fieldCode="AU" term="%22Dunstan+IK%22">Dunstan IK</searchLink>; Department of Pharmacology, Medical Sciences Division, University of Oxford, Mansfield Road, Oxford, OX1 3QT, UK.; Department of Chemistry, Mathematical, Physical & Life Sciences Division, University of Oxford, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22Rasmussen+LJH%22">Rasmussen LJH</searchLink>; Department of Clinical Research, Copenhagen University Hospital, Hvidovre, Denmark.<br /><searchLink fieldCode="AU" term="%22Probert+F%22">Probert F</searchLink>; Department of Chemistry, Mathematical, Physical & Life Sciences Division, University of Oxford, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22Olsen+DA%22">Olsen DA</searchLink>; Department of Biochemistry and Immunology, Lillebaelt Hospital, University Hospital of Southern Denmark, Vejle, Denmark.<br /><searchLink fieldCode="AU" term="%22Madsen+JS%22">Madsen JS</searchLink>; Department of Biochemistry and Immunology, Lillebaelt Hospital, University Hospital of Southern Denmark, Vejle, Denmark.; Department of Regional Health Research, Faculty of Health Sciences, University of Southern Denmark, Odense, Denmark.<br /><searchLink fieldCode="AU" term="%22Eugen-Olsen+J%22">Eugen-Olsen J</searchLink>; Department of Clinical Research, Copenhagen University Hospital, Hvidovre, Denmark.; Department of Cardiology, Copenhagen University Hospital-Herlev and Gentofte Hospital, Herlev, Denmark.<br /><searchLink fieldCode="AU" term="%22Enggaard+TP%22">Enggaard TP</searchLink>; Department of Anaesthesia, Multidiciplinary Pain Center, Copenhagen University Hospital, Copenhagen, Denmark.<br /><searchLink fieldCode="AU" term="%22Varnum+C%22">Varnum C</searchLink>; Department of Regional Health Research, Faculty of Health Sciences, University of Southern Denmark, Odense, Denmark.; Department of Orthopedic Surgery, Lillebaelt Hospital, University Hospital of Southern Denmark, Vejle, Denmark.<br /><searchLink fieldCode="AU" term="%22Lambertsen+KL%22">Lambertsen KL</searchLink>; Department of Neurology, Odense University Hospital, Odense, Denmark.; Department of Neurobiology Research, Institute of Molecular Medicine, University of Southern Denmark, Odense, Denmark.; BRIDGE, Brain Research-Inter Disciplinary Guided Excellence, Department of Clinical Research, University of Southern Denmark, Odense, Denmark.<br /><searchLink fieldCode="AU" term="%22Anthony+DC%22">Anthony DC</searchLink>; Department of Pharmacology, Medical Sciences Division, University of Oxford, Mansfield Road, Oxford, OX1 3QT, UK. daniel.anthony@pharm.ox.ac.uk.<br /><searchLink fieldCode="AU" term="%22Blichfeldt-Eckhardt+MR%22">Blichfeldt-Eckhardt MR</searchLink>; Department of Regional Health Research, Faculty of Health Sciences, University of Southern Denmark, Odense, Denmark.; Department of Anaesthesia, Lillebaelt Hospital, University Hospital of Southern Denmark, Vejle, Denmark.
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              Text: 2026 Jun 19
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