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Application of chimeric mice with human hepatocytes for the evaluation of metabolically activated genotoxic substances.

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Bibliographic Details
Title: Application of chimeric mice with human hepatocytes for the evaluation of metabolically activated genotoxic substances.
Authors: Fujikawa M; Advanced Research Laboratory for Fundamental Technologies, Sumitomo Chemical Co., Ltd., 1-98, Kasugadenaka 3-chome, Konohana-ku, Osaka, 554-8558, Japan. fujikawam2@sc.sumitomo-chem.co.jp., Matsuyama R; Advanced Research Laboratory for Fundamental Technologies, Sumitomo Chemical Co., Ltd., 1-98, Kasugadenaka 3-chome, Konohana-ku, Osaka, 554-8558, Japan., Yamasaki C; PhoenixBio Co., Ltd., 3-4-1, Kagamiyama, Higashi-Hiroshima, 739-0046, Japan., Tateno C; PhoenixBio Co., Ltd., 3-4-1, Kagamiyama, Higashi-Hiroshima, 739-0046, Japan.; Graduate School of Biomedical and Health Sciences, Hiroshima University, 1-2- 3, Kasumi, Minami-ku, Hiroshima, 734-8553, Japan.; School of Pharmaceutical Sciences, Wakayama Medical University, 25-1, Shichibancho, Wakayama, 640-8156, Japan., Asano H; Advanced Research Laboratory for Fundamental Technologies, Sumitomo Chemical Co., Ltd., 1-98, Kasugadenaka 3-chome, Konohana-ku, Osaka, 554-8558, Japan.
Source: Genes and environment : the official journal of the Japanese Environmental Mutagen Society [Genes Environ] 2026 Jun 19. Date of Electronic Publication: 2026 Jun 19.
Publication Type: Journal Article
Journal Info: Publisher: BioMed Central Country of Publication: England NLM ID: 101285347 Publication Model: Print-Electronic Cited Medium: Print ISSN: 1880-7046 (Print) Linking ISSN: 18807046 NLM ISO Abbreviation: Genes Environ
Database: MEDLINE Ultimate
Description
ISSN:1880-7046
DOI:10.1186/s41021-026-00362-2