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Network pharmacology and molecular dynamics simulations reveal shared mechanisms and myopia-specific targets of atropine in myopia and dry eye disease.

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Title: Network pharmacology and molecular dynamics simulations reveal shared mechanisms and myopia-specific targets of atropine in myopia and dry eye disease.
Authors: Lin M; National Clinical Research Center for Ocular Diseases, Eye Hospital, Wenzhou Medical University, Wenzhou, 325027, Zhejiang, China.; School of Ophthalmology and Optometry, Wenzhou Medical University, Wenzhou, 325035, Zhejiang, China., Shu W; National Clinical Research Center for Ocular Diseases, Eye Hospital, Wenzhou Medical University, Wenzhou, 325027, Zhejiang, China.; School of Ophthalmology and Optometry, Wenzhou Medical University, Wenzhou, 325035, Zhejiang, China., Hua G; National Clinical Research Center for Ocular Diseases, Eye Hospital, Wenzhou Medical University, Wenzhou, 325027, Zhejiang, China.; School of Ophthalmology and Optometry, Wenzhou Medical University, Wenzhou, 325035, Zhejiang, China., Duan Z; National Clinical Research Center for Ocular Diseases, Eye Hospital, Wenzhou Medical University, Wenzhou, 325027, Zhejiang, China.; School of Ophthalmology and Optometry, Wenzhou Medical University, Wenzhou, 325035, Zhejiang, China., Qu J; National Clinical Research Center for Ocular Diseases, Eye Hospital, Wenzhou Medical University, Wenzhou, 325027, Zhejiang, China. qujia@eye.ac.cn.; School of Ophthalmology and Optometry, Wenzhou Medical University, Wenzhou, 325035, Zhejiang, China. qujia@eye.ac.cn., Hu L; National Clinical Research Center for Ocular Diseases, Eye Hospital, Wenzhou Medical University, Wenzhou, 325027, Zhejiang, China. huliang@eye.ac.cn.; School of Ophthalmology and Optometry, Wenzhou Medical University, Wenzhou, 325035, Zhejiang, China. huliang@eye.ac.cn.
Source: Eye and vision (London, England) [Eye Vis (Lond)] 2026 Jun 22; Vol. 13 (1). Date of Electronic Publication: 2026 Jun 22.
Publication Type: Journal Article
Journal Info: Publisher: BioMed Central Country of Publication: England NLM ID: 101664982 Publication Model: Electronic Cited Medium: Print ISSN: 2326-0254 (Print) Linking ISSN: 23260254 NLM ISO Abbreviation: Eye Vis (Lond) Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:2326-0254
DOI:10.1186/s40662-026-00493-1