Comparison of efficacy and safety between long-acting growth hormone and short-acting growth hormone in isolated growth hormone deficiency: a systematic review and meta-analysis of 16 randomized controlled trials involving 2,435 pediatric patients.

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Title: Comparison of efficacy and safety between long-acting growth hormone and short-acting growth hormone in isolated growth hormone deficiency: a systematic review and meta-analysis of 16 randomized controlled trials involving 2,435 pediatric patients.
Authors: Shen ZZ; Department of Pediatrics, Shanghai Xuhui District Central Hospital, Shanghai, China., Huang Y; Department of Pediatrics, Shanghai Xuhui District Central Hospital, Shanghai, China., Wu LL; Department of Pediatrics, Shanghai Xuhui District Central Hospital, Shanghai, China., Zhang JS; Department of Pediatrics, Shanghai Xuhui District Central Hospital, Shanghai, China., Zhang XX; Department of Pediatrics, Tongde Hospital of Zhejiang Province, Hangzhou, China.
Source: Frontiers in pediatrics [Front Pediatr] 2026 Jun 04; Vol. 14, pp. 1776186. Date of Electronic Publication: 2026 Jun 04 (Print Publication: 2026).
Publication Type: Journal Article
Journal Info: Publisher: Frontiers Media SA Country of Publication: Switzerland NLM ID: 101615492 Publication Model: eCollection Cited Medium: Print ISSN: 2296-2360 (Print) Linking ISSN: 22962360 NLM ISO Abbreviation: Front Pediatr Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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ISSN:2296-2360
DOI:10.3389/fped.2026.1776186