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Comparison of efficacy and safety between long-acting growth hormone and short-acting growth hormone in isolated growth hormone deficiency: a systematic review and meta-analysis of 16 randomized controlled trials involving 2,435 pediatric patients.

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Title: Comparison of efficacy and safety between long-acting growth hormone and short-acting growth hormone in isolated growth hormone deficiency: a systematic review and meta-analysis of 16 randomized controlled trials involving 2,435 pediatric patients.
Authors: Shen ZZ; Department of Pediatrics, Shanghai Xuhui District Central Hospital, Shanghai, China., Huang Y; Department of Pediatrics, Shanghai Xuhui District Central Hospital, Shanghai, China., Wu LL; Department of Pediatrics, Shanghai Xuhui District Central Hospital, Shanghai, China., Zhang JS; Department of Pediatrics, Shanghai Xuhui District Central Hospital, Shanghai, China., Zhang XX; Department of Pediatrics, Tongde Hospital of Zhejiang Province, Hangzhou, China.
Source: Frontiers in pediatrics [Front Pediatr] 2026 Jun 04; Vol. 14, pp. 1776186. Date of Electronic Publication: 2026 Jun 04 (Print Publication: 2026).
Publication Type: Journal Article
Journal Info: Publisher: Frontiers Media SA Country of Publication: Switzerland NLM ID: 101615492 Publication Model: eCollection Cited Medium: Print ISSN: 2296-2360 (Print) Linking ISSN: 22962360 NLM ISO Abbreviation: Front Pediatr Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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  Data: Comparison of efficacy and safety between long-acting growth hormone and short-acting growth hormone in isolated growth hormone deficiency: a systematic review and meta-analysis of 16 randomized controlled trials involving 2,435 pediatric patients.
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  Data: <searchLink fieldCode="AU" term="%22Shen+ZZ%22">Shen ZZ</searchLink>; Department of Pediatrics, Shanghai Xuhui District Central Hospital, Shanghai, China.<br /><searchLink fieldCode="AU" term="%22Huang+Y%22">Huang Y</searchLink>; Department of Pediatrics, Shanghai Xuhui District Central Hospital, Shanghai, China.<br /><searchLink fieldCode="AU" term="%22Wu+LL%22">Wu LL</searchLink>; Department of Pediatrics, Shanghai Xuhui District Central Hospital, Shanghai, China.<br /><searchLink fieldCode="AU" term="%22Zhang+JS%22">Zhang JS</searchLink>; Department of Pediatrics, Shanghai Xuhui District Central Hospital, Shanghai, China.<br /><searchLink fieldCode="AU" term="%22Zhang+XX%22">Zhang XX</searchLink>; Department of Pediatrics, Tongde Hospital of Zhejiang Province, Hangzhou, China.
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  Data: <searchLink fieldCode="JN" term="%22101615492%22">Frontiers in pediatrics</searchLink> [Front Pediatr] 2026 Jun 04; Vol. 14, pp. 1776186. <i>Date of Electronic Publication: </i>2026 Jun 04 (<i>Print Publication: </i>2026).
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Frontiers+Media+SA%22">Frontiers Media SA </searchLink><i>Country of Publication: </i>Switzerland <i>NLM ID: </i>101615492 <i>Publication Model: </i>eCollection <i>Cited Medium: </i>Print <i>ISSN: </i>2296-2360 (Print) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2222962360%22">22962360 </searchLink><i>NLM ISO Abbreviation: </i>Front Pediatr <i>Subsets: </i>PubMed not MEDLINE
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        Value: 10.3389/fped.2026.1776186
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      – Code: eng
        Text: English
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        StartPage: 1776186
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      – TitleFull: Comparison of efficacy and safety between long-acting growth hormone and short-acting growth hormone in isolated growth hormone deficiency: a systematic review and meta-analysis of 16 randomized controlled trials involving 2,435 pediatric patients.
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            – D: 04
              M: 06
              Text: 2026 Jun 04
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