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Causal Relationship Between Methotrexate and Chronic Obstructive Pulmonary Disease: A Study Based on Network Toxicology and Mendelian Randomization.

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Bibliographic Details
Title: Causal Relationship Between Methotrexate and Chronic Obstructive Pulmonary Disease: A Study Based on Network Toxicology and Mendelian Randomization.
Authors: Xiang YX; State Key Laboratory of Traditional Chinese Medicine Syndrome, The First Clinical Medical College of Guangzhou University of Chinese Medicine, Guangzhou, People's Republic of China.; Department of Rheumatology, The First Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, People's Republic of China.; Guangdong Clinical Research Academy of Chinese Medicine, Guangzhou, People's Republic of China., Zou FS; State Key Laboratory of Traditional Chinese Medicine Syndrome, The First Clinical Medical College of Guangzhou University of Chinese Medicine, Guangzhou, People's Republic of China.; Department of Rheumatology, The First Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, People's Republic of China.; Guangdong Clinical Research Academy of Chinese Medicine, Guangzhou, People's Republic of China., Shi MF; State Key Laboratory of Traditional Chinese Medicine Syndrome, The First Clinical Medical College of Guangzhou University of Chinese Medicine, Guangzhou, People's Republic of China.; Department of Rheumatology, The First Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, People's Republic of China.; Guangdong Clinical Research Academy of Chinese Medicine, Guangzhou, People's Republic of China., Xu Q; State Key Laboratory of Traditional Chinese Medicine Syndrome, The First Clinical Medical College of Guangzhou University of Chinese Medicine, Guangzhou, People's Republic of China.; Department of Rheumatology, The First Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, People's Republic of China.; Guangdong Clinical Research Academy of Chinese Medicine, Guangzhou, People's Republic of China.
Source: International journal of chronic obstructive pulmonary disease [Int J Chron Obstruct Pulmon Dis] 2026 Jun 15; Vol. 21, pp. 615799. Date of Electronic Publication: 2026 Jun 15 (Print Publication: 2026).
Publication Type: Journal Article
Journal Info: Publisher: DOVE Medical Press Country of Publication: New Zealand NLM ID: 101273481 Publication Model: eCollection Cited Medium: Internet ISSN: 1178-2005 (Electronic) Linking ISSN: 11769106 NLM ISO Abbreviation: Int J Chron Obstruct Pulmon Dis Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1178-2005
DOI:10.2147/COPD.S615799