Probing the limits of genetic recoding using multi-omics-guided evolution.
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| Title: | Probing the limits of genetic recoding using multi-omics-guided evolution. |
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| Authors: | Nyerges A; Department of Genetics, Harvard Medical School, Boston, MA, USA. akos_nyerges@hms.harvard.edu., Chiappino-Pepe A; Department of Genetics, Harvard Medical School, Boston, MA, USA., Budnik B; Wyss Institute for Biologically Inspired Engineering, Harvard University, Boston, MA, USA., Baas-Thomas M; Department of Genetics, Harvard Medical School, Boston, MA, USA., Rhuby E; Department of Genetics, Harvard Medical School, Boston, MA, USA., Flynn R; Department of Genetics, Harvard Medical School, Boston, MA, USA., Yan S; Department of Genetics, Harvard Medical School, Boston, MA, USA.; BGI Research, Shenzhen, China., Ostrov N; Department of Genetics, Harvard Medical School, Boston, MA, USA., Liu M; GenScript USA Inc., Piscataway, NJ, USA., Wang M; GenScript USA Inc., Piscataway, NJ, USA., Zheng Q; GenScript USA Inc., Piscataway, NJ, USA., Hu F; GenScript USA Inc., Piscataway, NJ, USA., Chen K; GenScript USA Inc., Piscataway, NJ, USA., Rudolph A; Department of Genetics, Harvard Medical School, Boston, MA, USA., Chen D; Department of Genetics, Harvard Medical School, Boston, MA, USA., Ahn J; Department of Genetics, Harvard Medical School, Boston, MA, USA., Spencer O; Department of Genetics, Harvard Medical School, Boston, MA, USA., Ayalavarapu V; Department of Genetics, Harvard Medical School, Boston, MA, USA., Tarver A; DOE Joint Genome Institute (JGI), Lawrence Berkeley National Laboratory, Berkeley, CA, USA., Harmon-Smith M; DOE Joint Genome Institute (JGI), Lawrence Berkeley National Laboratory, Berkeley, CA, USA., Hamilton M; DOE Joint Genome Institute (JGI), Lawrence Berkeley National Laboratory, Berkeley, CA, USA., Blaby I; DOE Joint Genome Institute (JGI), Lawrence Berkeley National Laboratory, Berkeley, CA, USA., Yoshikuni Y; DOE Joint Genome Institute (JGI), Lawrence Berkeley National Laboratory, Berkeley, CA, USA., Hajian B; Center for the Development of Therapeutics, Broad Institute of MIT and Harvard, Cambridge, MA, USA., Jin A; GenScript USA Inc., Piscataway, NJ, USA., Kintses B; Institute of Biochemistry, HUN-REN Biological Research Centre, Szeged, Hungary., Szamel M; Institute of Biochemistry, HUN-REN Biological Research Centre, Szeged, Hungary., Seregi V; Institute of Biochemistry, HUN-REN Biological Research Centre, Szeged, Hungary., Shen Y; BGI Research, Shenzhen, China.; BGI Research, Changzhou, China.; Guangdong Provincial Key Laboratory of Genome Read and Write, BGI Research, Shenzhen, China., Li Z; GenScript USA Inc., Piscataway, NJ, USA., Church GM; Department of Genetics, Harvard Medical School, Boston, MA, USA. gchurch@genetics.med.harvard.edu.; Wyss Institute for Biologically Inspired Engineering, Harvard University, Boston, MA, USA. gchurch@genetics.med.harvard.edu. |
| Source: | Nature communications [Nat Commun] 2026 Jun 22; Vol. 17 (1). Date of Electronic Publication: 2026 Jun 22. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 2041-1723 |
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| DOI: | 10.1038/s41467-026-74300-9 |
