Novel role of the class II α-isoform of phosphatidylinositol 3-kinase in hepatocellular carcinoma: suppressing metastasis by targeting Wnt/β-catenin signaling via inhibiting phosphorylation of LRP6.
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| Title: | Novel role of the class II α-isoform of phosphatidylinositol 3-kinase in hepatocellular carcinoma: suppressing metastasis by targeting Wnt/β-catenin signaling via inhibiting phosphorylation of LRP6. |
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| Authors: | Chen J; Department of breast surgery, Shanxi Cancer Hospital, Taiyuan, Shanxi, China., Ren LX; Department of Hepatobiliary, Pancreatic and Gastrointestinal Surgery, Shanxi Cancer Hospital, Taiyuan, Shanxi, China., Ma Y; Department of Thoracic surgery, Shanxi Cancer Hospital, Taiyuan, Shanxi, China., Cheng WH; Department of Gastroenterology, Shanxi Cancer Hospital, Taiyuan, Shanxi, China., Liu T; Department of Hepatobiliary, Pancreatic and Gastrointestinal Surgery, Shanxi Cancer Hospital, Taiyuan, Shanxi, China. liutingchenjing@163.com.; Department of General Surgery, Shanxi Hospital Affiliated to Cancer Hospital, Shanxi Cancer Hospital, Chinese Academy of Medical Sciences, Cancer Hospital Affiliated to Shanxi Medical University, Taiyuan, 030032, China. liutingchenjing@163.com. |
| Source: | Cancer cell international [Cancer Cell Int] 2026 Jun 22. Date of Electronic Publication: 2026 Jun 22. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: BioMed Central Country of Publication: England NLM ID: 101139795 Publication Model: Print-Electronic Cited Medium: Print ISSN: 1475-2867 (Print) Linking ISSN: 14752867 NLM ISO Abbreviation: Cancer Cell Int |
| Database: | MEDLINE Ultimate |
| ISSN: | 1475-2867 |
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| DOI: | 10.1186/s12935-026-04368-2 |
