Use of Sedative-Hypnotic Drugs and the Risk of Developing Alzheimer's Disease: A Systematic Review, Meta-Analysis and Meta-Regression.

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Bibliographic Details
Title: Use of Sedative-Hypnotic Drugs and the Risk of Developing Alzheimer's Disease: A Systematic Review, Meta-Analysis and Meta-Regression.
Authors: da Silva AMP; Department of Physiology and Pharmacology, Federal University of Pernambuco, Professor Moraes Rego Avenue, University City, Recife, PE, 50670-420, Brazil. anderson.matheuss@ufpe.br., Tudella GCN; Department of Medicine, Federal University of Santa Maria, Santa Maria, RS, Brazil., Gonçalves OR; Department of Medicine, Federal University of Piauí, Teresina, PI, Brazil., Ribeiro FV; Department of Medicine, Faculty of Medicine, Barão de Mauá University Center, Ribeirão Preto, SP, Brazil., Pereira MAOM; Department of Medicine, State University of Piauí, Teresina, PI, Brazil., do Nascimento MDVS; Center for Medical Sciences, Graduate Program in Translational Health, Federal University of Pernambuco, Recife, PE, Brazil., Nogueira BV; Lyerly Neurosurgery, Baptist Neurological Institute, Jacksonville, Florida, USA., Santos DH; Department of Neurology, University of São Paulo, São Paulo, SP, Brazil., de Gobbi Porto FH; Department and Institute of Psychiatry, Hospital das Clínicas, Faculty of Medicine, University of São Paulo, São Paulo, Brazil., Høilund-Carlsen PF; Department of Nuclear Medicine, Odense University Hospital, Odense, Denmark.; Department of Clinical Research, University of Southern Denmark, Odense, Denmark., Duarte FS; Department of Physiology and Pharmacology, Federal University of Pernambuco, Professor Moraes Rego Avenue, University City, Recife, PE, 50670-420, Brazil., Perry G; Department of Neurosciences, Developmental and Regenerative Biology, University of Texas at San Antonio, San Antonio, TX, USA., de Souza Franco E; Center for Medical Sciences, Graduate Program in Translational Health, Federal University of Pernambuco, Recife, PE, Brazil., de Sousa Maia MB; Department of Physiology and Pharmacology, Federal University of Pernambuco, Professor Moraes Rego Avenue, University City, Recife, PE, 50670-420, Brazil.; Center for Medical Sciences, Graduate Program in Translational Health, Federal University of Pernambuco, Recife, PE, Brazil.
Source: Drugs [Drugs] 2026 Jul; Vol. 86 (7), pp. 1103-1119. Date of Electronic Publication: 2026 May 27.
Publication Type: Journal Article; Systematic Review; Meta-Analysis
Journal Info: Publisher: Adis, Springer International Country of Publication: New Zealand NLM ID: 7600076 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1179-1950 (Electronic) Linking ISSN: 00126667 NLM ISO Abbreviation: Drugs Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1179-1950
DOI:10.1007/s40265-026-02335-9