Diacylglycerol kinase ζ in B lymphocytes supports CD40-mediated immune synapse formation, mTORC1 signaling, and plasma cell fate.
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| Title: | Diacylglycerol kinase ζ in B lymphocytes supports CD40-mediated immune synapse formation, mTORC1 signaling, and plasma cell fate. |
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| Authors: | Fernández-Barrecheguren A; B Lymphocyte Dynamics, Department of Immunology and Oncology, Centro Nacional de Biotecnología (CNB)-CSIC, Madrid, Spain.; Molecular Biosciences Program, Faculty of Sciences, Universidad Autónoma de Madrid (UAM), Madrid, Spain., Fernández-Rego A; B Lymphocyte Dynamics, Department of Immunology and Oncology, Centro Nacional de Biotecnología (CNB)-CSIC, Madrid, Spain.; Molecular Biosciences Program, Faculty of Sciences, Universidad Autónoma de Madrid (UAM), Madrid, Spain., Fuentes-Cantos L; B Lymphocyte Dynamics, Department of Immunology and Oncology, Centro Nacional de Biotecnología (CNB)-CSIC, Madrid, Spain.; Molecular Biosciences Program, Faculty of Sciences, Universidad Autónoma de Madrid (UAM), Madrid, Spain., Pons T; Department of Immunology and Oncology, CNB-CSIC, Madrid, Spain., Estrada BS; Organ and Tissue Homeostasis Program, Centro de Biología Molecular Severo Ochoa (CBMSO), CSIC-UAM, Madrid, Spain., Iborra-Pernichi M; Organ and Tissue Homeostasis Program, Centro de Biología Molecular Severo Ochoa (CBMSO), CSIC-UAM, Madrid, Spain., de la Esperanza MV; Organ and Tissue Homeostasis Program, Centro de Biología Molecular Severo Ochoa (CBMSO), CSIC-UAM, Madrid, Spain., Ebrahimi T; CBMSO, CSIC-UAM, Institute for Molecular Biology-IUBM, UAM, Madrid, Spain., Sagrega-Aparisi A; CBMSO, CSIC-UAM, Institute for Molecular Biology-IUBM, UAM, Madrid, Spain., Cogliati S; CBMSO, CSIC-UAM, Institute for Molecular Biology-IUBM, UAM, Madrid, Spain., Martínez-Martín N; Organ and Tissue Homeostasis Program, Centro de Biología Molecular Severo Ochoa (CBMSO), CSIC-UAM, Madrid, Spain., Jiménez-Saiz R; Department of Immunology, Instituto de Investigación Sanitaria Hospital Universitario de La Princesa (IIS-Princesa), Madrid, Spain., Carrasco YR; B Lymphocyte Dynamics, Department of Immunology and Oncology, Centro Nacional de Biotecnología (CNB)-CSIC, Madrid, Spain. |
| Source: | Science signaling [Sci Signal] 2026 Jun 23; Vol. 19 (943), pp. eadw1017. Date of Electronic Publication: 2026 Jun 23. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 101465400 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1937-9145 (Electronic) Linking ISSN: 19450877 NLM ISO Abbreviation: Sci Signal Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 1937-9145 |
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| DOI: | 10.1126/scisignal.adw1017 |
