PEGylation-associated hemodynamic effects in a rodent model of acute hypersensitivity reaction: Complement activation-mediated mechanisms.

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Title: PEGylation-associated hemodynamic effects in a rodent model of acute hypersensitivity reaction: Complement activation-mediated mechanisms.
Authors: Ngo ST; Graduate Institute of Biomedical Sciences, College of Medicine, Chang Gung University, Guishan, Taoyuan, 33302, Taiwan, ROC; Department of Physiology and Pharmacology, Chang Gung University, Guishan, Taoyuan, 33302, Taiwan, ROC., Cheng Y; Graduate Institute of Biomedical Sciences, College of Medicine, Chang Gung University, Guishan, Taoyuan, 33302, Taiwan, ROC; Department of Physiology and Pharmacology, Chang Gung University, Guishan, Taoyuan, 33302, Taiwan, ROC., Chen SY; Department of Physiology and Pharmacology, Chang Gung University, Guishan, Taoyuan, 33302, Taiwan, ROC., Sun MT; Department of Mechanical Engineering, Chang Gung University, Guishan, Taoyuan, 33302, Taiwan, ROC., Yu JS; Molecular Medicine Research Center, Chang Gung University, Guishan, Taoyuan, 33302, Taiwan, ROC., Chien KY; Molecular Medicine Research Center, Chang Gung University, Guishan, Taoyuan, 33302, Taiwan, ROC., Chen HM; Department of Physiology and Pharmacology, Chang Gung University, Guishan, Taoyuan, 33302, Taiwan, ROC., Ma YH; Department of Physiology and Pharmacology, Chang Gung University, Guishan, Taoyuan, 33302, Taiwan, ROC; Department of Medical Imaging and Intervention, Chang Gung Memorial Hospital, Guishan, Taoyuan, 33305, Taiwan, ROC. Electronic address: yhma@mail.cgu.edu.tw.
Source: Nanomedicine : nanotechnology, biology, and medicine [Nanomedicine] 2026 Jul; Vol. 75, pp. 102983. Date of Electronic Publication: 2026 Jun 23.
Publication Type: Journal Article
Journal Info: Publisher: Elsevier Country of Publication: United States NLM ID: 101233142 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1549-9642 (Electronic) Linking ISSN: 15499634 NLM ISO Abbreviation: Nanomedicine Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:1549-9642
DOI:10.1016/j.nano.2026.102983