Application of a Novel Desirability of Outcome Ranking Endpoint Incorporating a Framework for Resistance Assessment and Microbiologic Evaluation in Antibiotic Trials: A Proof-of-Concept in a Post Hoc Analysis of the BALANCE Trial.
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| Title: | Application of a Novel Desirability of Outcome Ranking Endpoint Incorporating a Framework for Resistance Assessment and Microbiologic Evaluation in Antibiotic Trials: A Proof-of-Concept in a Post Hoc Analysis of the BALANCE Trial. |
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| Authors: | Ong SWX; Institute of Health Policy, Management and Evaluation, University of Toronto, Toronto, Ontario, Canada.; Department of Infectious Diseases, University of Melbourne, at the Peter Doherty Institute for Infection and Immunity, Melbourne, Victoria, Australia.; Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada.; Victorian Infectious Diseases Service, Royal Melbourne Hospital, Peter Doherty Institute for Infection and Immunity, Melbourne, Victoria, Australia.; ICES, Toronto, Ontario, Canada., Patrikar A; ICES, Toronto, Ontario, Canada., Pinto R; Institute of Health Policy, Management and Evaluation, University of Toronto, Toronto, Ontario, Canada.; Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada., Mahar RK; Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, University of Melbourne, Parkville, Victoria, Australia.; Clinical Epidemiology and Biostatistics Unit, Murdoch Children's Research Institute, Parkville, Victoria, Australia.; Methods and Implementation Support for Clinical and Health Research Hub, University of Melbourne, Parkville, Victoria, Australia., Rishu A; Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada., Davis JS; School of Medicine and Public Health, University of Newcastle, Newcastle, New South Wales, Australia.; Department of Immunology and Infectious Diseases, John Hunter Hospital, Newcastle, New South Wales, Australia.; Global and Tropical Health Division, Menzies School of Health and Research, Darwin, Northern Territory, Australia., Fowler RA; Institute of Health Policy, Management and Evaluation, University of Toronto, Toronto, Ontario, Canada.; Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada., Tong SYC; Department of Infectious Diseases, University of Melbourne, at the Peter Doherty Institute for Infection and Immunity, Melbourne, Victoria, Australia.; Victorian Infectious Diseases Service, Royal Melbourne Hospital, Peter Doherty Institute for Infection and Immunity, Melbourne, Victoria, Australia., Daneman N; Institute of Health Policy, Management and Evaluation, University of Toronto, Toronto, Ontario, Canada.; Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada.; ICES, Toronto, Ontario, Canada. |
| Source: | Open forum infectious diseases [Open Forum Infect Dis] 2026 Jun 22; Vol. 13 (6), pp. ofag142. Date of Electronic Publication: 2026 Jun 22 (Print Publication: 2026). |
| Publication Type: | Clinical Trial; Journal Article |
| Journal Info: | Publisher: Published by Oxford University Press on behalf of the Infectious Diseases Society of America Country of Publication: United States NLM ID: 101637045 Publication Model: eCollection Cited Medium: Print ISSN: 2328-8957 (Print) Linking ISSN: 23288957 NLM ISO Abbreviation: Open Forum Infect Dis Subsets: PubMed not MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 2328-8957 |
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| DOI: | 10.1093/ofid/ofag142 |
