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Practical approach to the diagnosis, management, and treatment of pediatric patients with bone fragility: an expert opinion.

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Title: Practical approach to the diagnosis, management, and treatment of pediatric patients with bone fragility: an expert opinion.
Authors: Baroncelli GI; Pediatric and Adolescent Endocrinology, Division of Pediatrics, Department of Obstetrics, Gynecology and Pediatrics, University Hospital, Pisa, Italy., Tessaris D; Pediatric Endocrinology, Department of Public Health and Pediatrics, University of Turin, Regina Margherita Children's Hospital, Turin, Italy., Aversa T; Department of Human Pathology of Adulthood and Childhood, University of Messina, Messina, Italy.; Pediatric Unit, University Hospital G. Martino, Messina, Italy., Bertelli E; Pediatric and Pediatric Emergency Unit, Children Hospital, Azienda Ospedaliero-Universitaria SS Antonio e Biagio e C. Arrigo, Alessandria, Italy., Comberiati P; Pediatric and Adolescent Endocrinology, Division of Pediatrics, Department of Obstetrics, Gynecology and Pediatrics, University Hospital, Pisa, Italy.; Department of Clinical and Experimental Medicine, Section of Pediatrics, University of Pisa, Pisa, Italy., Corica D; Department of Human Pathology of Adulthood and Childhood, University of Messina, Messina, Italy., Di Iorgi N; Department of Pediatrics, IRCCS Istituto Giannina Gaslini, Genova, Italy.; Department of Neuroscience, Rehabilitation, Ophthalmology, Genetics, Maternal and Child Health, University of Genova, Genova, Italy., Faienza MF; Pediatric Unit, Department of Precision and Regenerative Medicine and Ionian Area, University of Bari 'Aldo Moro', Bari, Italy., Fintini D; Endocrinology and Diabetology Unit, Bambino Gesù Children Hospital, IRCCS, Rome, Italy., Franceschi R; Centre for Medical Sciences -CISMed, University of Trento, Trento, Italy., Grandone A; Department of Child Woman, General and Specialized Surgery, University of Campania 'L. Vanvitelli', Naples, Italy., Karapurackal MA; Department of Pediatrics, Hospital of Bolzano (SABES-ASDAA), Teaching Hospital of Paracelsus Medical University (PMU), Bolzano, Italy., Longhi S; Department of Pediatrics, Hospital of Bolzano (SABES-ASDAA), Teaching Hospital of Paracelsus Medical University (PMU), Bolzano, Italy., Pitea M; Pediatric Endocrinology Unit, Department of Pediatrics, IRCCS Ospedale San Raffaele, Milan, Italy., Secco A; Pediatric and Pediatric Emergency Unit, Children Hospital, Azienda Ospedaliero-Universitaria SS Antonio e Biagio e C. Arrigo, Alessandria, Italy., Trifirò G; Cardiovascular Genetic Centre, IRCCS, Policlinico, San Donato Milanese, Italy., Ubertini G; Endocrinology and Diabetology Unit, Bambino Gesù Children Hospital, IRCCS, Rome, Italy., Urbano F; Giovanni XXIII Pediatric Hospital, University of Bari 'Aldo Moro', Bari, Italy., Vierucci F; Pediatric Unit San Luca Hospital, Lucca, Italy., Wasniewska M; Department of Human Pathology of Adulthood and Childhood, University of Messina, Messina, Italy., Mora S; Laboratory of Pediatric Endocrinology, Department of Pediatrics, IRCCS Ospedale San Raffaele, Milan, Italy., de Sanctis L; Pediatric Endocrinology, Department of Public Health and Pediatrics, University of Turin, Regina Margherita Children's Hospital, Turin, Italy. luisa.desanctis@unito.it.
Source: Journal of endocrinological investigation [J Endocrinol Invest] 2026 Jun 24. Date of Electronic Publication: 2026 Jun 24.
Publication Type: Journal Article
Journal Info: Publisher: Springer Country of Publication: Italy NLM ID: 7806594 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1720-8386 (Electronic) Linking ISSN: 03914097 NLM ISO Abbreviation: J Endocrinol Invest Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Practical approach to the diagnosis, management, and treatment of pediatric patients with bone fragility: an expert opinion.
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  Data: <searchLink fieldCode="AU" term="%22Baroncelli+GI%22">Baroncelli GI</searchLink>; Pediatric and Adolescent Endocrinology, Division of Pediatrics, Department of Obstetrics, Gynecology and Pediatrics, University Hospital, Pisa, Italy.<br /><searchLink fieldCode="AU" term="%22Tessaris+D%22">Tessaris D</searchLink>; Pediatric Endocrinology, Department of Public Health and Pediatrics, University of Turin, Regina Margherita Children's Hospital, Turin, Italy.<br /><searchLink fieldCode="AU" term="%22Aversa+T%22">Aversa T</searchLink>; Department of Human Pathology of Adulthood and Childhood, University of Messina, Messina, Italy.; Pediatric Unit, University Hospital G. Martino, Messina, Italy.<br /><searchLink fieldCode="AU" term="%22Bertelli+E%22">Bertelli E</searchLink>; Pediatric and Pediatric Emergency Unit, Children Hospital, Azienda Ospedaliero-Universitaria SS Antonio e Biagio e C. Arrigo, Alessandria, Italy.<br /><searchLink fieldCode="AU" term="%22Comberiati+P%22">Comberiati P</searchLink>; Pediatric and Adolescent Endocrinology, Division of Pediatrics, Department of Obstetrics, Gynecology and Pediatrics, University Hospital, Pisa, Italy.; Department of Clinical and Experimental Medicine, Section of Pediatrics, University of Pisa, Pisa, Italy.<br /><searchLink fieldCode="AU" term="%22Corica+D%22">Corica D</searchLink>; Department of Human Pathology of Adulthood and Childhood, University of Messina, Messina, Italy.<br /><searchLink fieldCode="AU" term="%22Di+Iorgi+N%22">Di Iorgi N</searchLink>; Department of Pediatrics, IRCCS Istituto Giannina Gaslini, Genova, Italy.; Department of Neuroscience, Rehabilitation, Ophthalmology, Genetics, Maternal and Child Health, University of Genova, Genova, Italy.<br /><searchLink fieldCode="AU" term="%22Faienza+MF%22">Faienza MF</searchLink>; Pediatric Unit, Department of Precision and Regenerative Medicine and Ionian Area, University of Bari 'Aldo Moro', Bari, Italy.<br /><searchLink fieldCode="AU" term="%22Fintini+D%22">Fintini D</searchLink>; Endocrinology and Diabetology Unit, Bambino Gesù Children Hospital, IRCCS, Rome, Italy.<br /><searchLink fieldCode="AU" term="%22Franceschi+R%22">Franceschi R</searchLink>; Centre for Medical Sciences -CISMed, University of Trento, Trento, Italy.<br /><searchLink fieldCode="AU" term="%22Grandone+A%22">Grandone A</searchLink>; Department of Child Woman, General and Specialized Surgery, University of Campania 'L. Vanvitelli', Naples, Italy.<br /><searchLink fieldCode="AU" term="%22Karapurackal+MA%22">Karapurackal MA</searchLink>; Department of Pediatrics, Hospital of Bolzano (SABES-ASDAA), Teaching Hospital of Paracelsus Medical University (PMU), Bolzano, Italy.<br /><searchLink fieldCode="AU" term="%22Longhi+S%22">Longhi S</searchLink>; Department of Pediatrics, Hospital of Bolzano (SABES-ASDAA), Teaching Hospital of Paracelsus Medical University (PMU), Bolzano, Italy.<br /><searchLink fieldCode="AU" term="%22Pitea+M%22">Pitea M</searchLink>; Pediatric Endocrinology Unit, Department of Pediatrics, IRCCS Ospedale San Raffaele, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Secco+A%22">Secco A</searchLink>; Pediatric and Pediatric Emergency Unit, Children Hospital, Azienda Ospedaliero-Universitaria SS Antonio e Biagio e C. Arrigo, Alessandria, Italy.<br /><searchLink fieldCode="AU" term="%22Trifirò+G%22">Trifirò G</searchLink>; Cardiovascular Genetic Centre, IRCCS, Policlinico, San Donato Milanese, Italy.<br /><searchLink fieldCode="AU" term="%22Ubertini+G%22">Ubertini G</searchLink>; Endocrinology and Diabetology Unit, Bambino Gesù Children Hospital, IRCCS, Rome, Italy.<br /><searchLink fieldCode="AU" term="%22Urbano+F%22">Urbano F</searchLink>; Giovanni XXIII Pediatric Hospital, University of Bari 'Aldo Moro', Bari, Italy.<br /><searchLink fieldCode="AU" term="%22Vierucci+F%22">Vierucci F</searchLink>; Pediatric Unit San Luca Hospital, Lucca, Italy.<br /><searchLink fieldCode="AU" term="%22Wasniewska+M%22">Wasniewska M</searchLink>; Department of Human Pathology of Adulthood and Childhood, University of Messina, Messina, Italy.<br /><searchLink fieldCode="AU" term="%22Mora+S%22">Mora S</searchLink>; Laboratory of Pediatric Endocrinology, Department of Pediatrics, IRCCS Ospedale San Raffaele, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22de+Sanctis+L%22">de Sanctis L</searchLink>; Pediatric Endocrinology, Department of Public Health and Pediatrics, University of Turin, Regina Margherita Children's Hospital, Turin, Italy. luisa.desanctis@unito.it.
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  Data: <searchLink fieldCode="JN" term="%227806594%22">Journal of endocrinological investigation</searchLink> [J Endocrinol Invest] 2026 Jun 24. <i>Date of Electronic Publication: </i>2026 Jun 24.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Springer%22">Springer </searchLink><i>Country of Publication: </i>Italy <i>NLM ID: </i>7806594 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1720-8386 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2203914097%22">03914097 </searchLink><i>NLM ISO Abbreviation: </i>J Endocrinol Invest <i>Subsets: </i>MEDLINE
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        Value: 10.1007/s40618-026-02882-8
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