Severe asthma and remission prospects in Europe (SHARP): insights from a multicentre observational study based on the European Severe Asthma Registry.

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Title: Severe asthma and remission prospects in Europe (SHARP): insights from a multicentre observational study based on the European Severe Asthma Registry.
Authors: Fouka E; Division for Lung and Airway Research, Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden; Lung Laboratory, Center for Molecular Medicine, Karolinska University Hospital, Stockholm, Sweden; 2nd Department of Respiratory Medicine, University General Hospital Attikon, National and Kapodistrian University of Athens, Athens, Greece., Bansal AT; Acclarogen, St John's Innovation Centre, Cambridge, UK., Håkansson KEJ; Department of Respiratory Medicine and Infectious Diseases - Bispebjerg, Copenhagen University Hospital, Copenhagen, Denmark., Jaun F; University Institute of Internal Medicine, Cantonal Hospital Baselland, Liestal, Switzerland; Faculty of Medicine, University of Basel, Basel, Switzerland., Louis R; Department of Pneumology-Allergology, CHU of Liège, GIGAI(3) Pneumology Research Group, Liège University, Liège, Belgium., Hanon S; UZ Brussel/Vrije Universiteit Brussel Lung Research Unit, Vitality Research Group, Vrije Universiteit Brussel, Brussels, Belgium; Respiratory Division, Universitair Ziekenhuis Brussel, Brussels, Belgium., Brusselle G; Department of Respiratory Medicine, Ghent University Hospital, Gent, Belgium., Ziant S; Department of Pneumology-Allergology, CHU of Liège, GIGAI(3) Pneumology Research Group, Liège University, Liège, Belgium., Paulus V; Department of Pneumology-Allergology, CHU of Liège, GIGAI(3) Pneumology Research Group, Liège University, Liège, Belgium., Popović-Grle S; Clinic for pulmonary diseases Jordanovac, University Hospital Centre Zagreb, Zagreb, Croatia; School of Medicine, University of Zagreb, Zagreb, Croatia., Pavlisa G; Clinic for pulmonary diseases Jordanovac, University Hospital Centre Zagreb, Zagreb, Croatia; School of Medicine, University of Zagreb, Zagreb, Croatia., Lampalo M; Clinic for pulmonary diseases Jordanovac, University Hospital Centre Zagreb, Zagreb, Croatia; School of Medicine, University of Zagreb, Zagreb, Croatia., Vergles M; Department of Pulmonology, University Hospital Dubrava, Zagreb, Croatia., Kasap EB; Department of Pulmonology, General Hospital Zadar, Zadar, Croatia., Sedlak V; Department of Pneumonology, University Hospital Hradec Králové, Hradec Králové, Czech Republic., Søndergaard M; Department of Respiratory Medicine and Infectious Diseases - Bispebjerg, Copenhagen University Hospital, Copenhagen, Denmark., Hansen S; Department of Respiratory Medicine and Infectious Diseases - Bispebjerg, Copenhagen University Hospital, Copenhagen, Denmark., Sergejeva S; The North Estonia Medical Centre, Tallinn, Estonia., Perotin JM; Université de Reims Champagne-Ardenne, INSERM, CHU de Reims, P3Cell UMR-S1250, Reims, France., Taillé C; Service de Pneumologie, Allergologie et Transplantation, Hôpital Bichat, AP-HP, Paris, France; INSERM UMR 1149, Université Paris Cité, CRISALIS Network, Paris, France., Devouassoux G; Service de Pneumologie, Hôpital de la Croix Rousse, HCL, CRISALIS F-CRIN network, VIRPATH INSERM 1111, Université Claude Bernard, Lyon, France., Giboin C; AP-HP, Hôpital Pitié Salpêtrière, INSERM, Centre de Pharmacoépidémiologie (Cephepi), Paris, France., Klising E; AP-HP, Hôpital Pitié Salpêtrière, INSERM, Centre de Pharmacoépidémiologie (Cephepi), Paris, France., Estellat C; Sorbonne Université, INSERM, Institut Pierre Louis d'Epidémiologie et de Santé Publique, équipe PEPITES, AP-HP, Hôpital Pitié Salpêtrière, Centre de Pharmacoépidémiologie (Cephépi), Paris, France., Metdaoui D; AP-HP, Hôpital Pitié Salpêtrière, INSERM, Centre de Pharmacoépidémiologie (Cephepi), Paris, France., Hamelmann E; Department of Paediatrics, Children's Center Bethel, University Hospital OWL, University Bielefeld, Bielefeld, Germany., Samitas K; 7th Respiratory Dept and Asthma Center, Athens Chest Hospital Sotiria, Athens, Greece., Porpodis K; Pulmonary Department, G Papanikolaou General Hospital, School of Medicine, Aristotle University of Thessaloniki, Thessaloniki, Greece., Zervas E; 7th Respiratory Dept and Asthma Center, Athens Chest Hospital Sotiria, Athens, Greece., Gaga M; 1st Respiratory Medicine Department, Hygeia Hospital, Athens, Greece., Csoma Z; National Koranyi Institute of Pulmonology, Budapest, Hungary., Horvath I; National Koranyi Institute of Pulmonology, Budapest, Hungary; Department of Pulmonology, University of Debrecen, Debrecen, Hungary., Lúdvíksdóttir D; Department of Respiratory Medicine, Landspítali University Hospital, University of Iceland, Reykjavík, Iceland., Sigurdardóttir KD; Department of Respiratory Medicine, Landspítali University Hospital, University of Iceland, Reykjavík, Iceland., Canonica GW; Department of Biomedical Sciences, Humanitas University, Pieve Emanuele, Milan, Italy; Personalized Medicine, Asthma and Allergy-IRCCS Humanitas Research Hospital, Rozzano, Milan, Italy., Heffler E; Department of Biomedical Sciences, Humanitas University, Pieve Emanuele, Milan, Italy; Personalized Medicine, Asthma and Allergy-IRCCS Humanitas Research Hospital, Rozzano, Milan, Italy., Cardini C; Fondazione per la Salute Respiratoria della Società Italiana di Pneumologia SIP-IRS, Milan, Italy., Alloni A; Biomeris SRL, Pavia, Italy., Kroiča I; Riga East Clinical University Hospital, Riga, Latvia., Matisa D; Pauls Stradiņš Clinical University Hospital, Riga, Latvia., Bieksiene K; Department of Pulmonology, Lithuanian University of Health Sciences, Kaunas, Lithuania., Palacionyte J; Department of Pulmonology, Lithuanian University of Health Sciences, Kaunas, Lithuania., Christian N; Information Technology for Translational Medicine SA, Esch sur Alzette, Luxembourg., Tching R; Information Technology for Translational Medicine SA, Esch sur Alzette, Luxembourg., Boudewijn I; Department of Pulmonology, Frisius Medical Center, Leeuwarden, Netherlands., Sont JK; Department of Biomedical Data Sciences, Caecilia Institute for Population Health and Data Sciences, Leiden University Medical Centre, Leiden, Netherlands., Hashimoto S; Department of Respiratory Medicine, Amsterdam University Medical Center,Amsterdam, Netherlands., Kuna P; Department of Internal Medicine, Asthma andAllergy, Medical Universityof Lodz, Lodz, Poland., Morawska M; Department of Internal Medicine, Asthma andAllergy, Medical Universityof Lodz, Lodz, Poland., Loureiro CC; Pulmonology Unit, Unidade Localde Saúde de Coimbra, EPE, Coimbra, Portugal; Faculdade de Medicina, Universidade de Coimbra, Coimbra, Portugal., Fonseca JA; RISE- Health Research Network, Department of Community Medicine, Information and Health Decisions, Faculty of Medicine of the University of Porto, Porto, Portugal., Canhoto D; Pulmonology Unit, Unidade Localde Saúde de Coimbra, EPE, Coimbra, Portugal; Faculdade de Medicina, Universidade de Coimbra, Coimbra, Portugal., Santos H; Department of Community Medicine, Information and Health Decision Sciences, Faculty of Medicine, University of Porto, Porto, Portugal., Mendes A; Serviço de Imunoalergologia, Departamento Torax, Unidade Multidisciplinar de Asma Grave, Unidade Local de Saúde Santa Maria, Lisbon, Portugal., Belchior I; Serviço de Pneumologia-ULS Algarve, Portimão, Portugal., Lopes C; Instituto de Saúde Ambiental, Faculdade de Medicina de Lisboa, Lisbon, Portugal; Unidade Multidisciplinar de Asma Grave, Unidade Local de Saúde Santa Maria, Lisbon, Portugal., Mihaltan F; National Institute of Pneumology, Bucharest, Romania., Hromis S; Faculty of Medicine, University of Novi Sad, Novi Sad, Serbia; Institute for Pulmonary Diseases of Vojvodina, Sremska Kamenica, Serbia., Stjepanovic M; Faculty of Medicine, University of Belgrade, Belgrade, Serbia; Clinic of Pulmonology, University Clinical Center of Serbia, Belgrade, Serbia., Cupurdija V; Department of Internal medicine, Faculty of Medical Sciences, University of Kragujevac, Kragujevac, Serbia; Clinic for Pulmonology, University Clinical Center Kragujevac, Kragujevac, Serbia., Tomic-Spiric V; Faculty of Medicine, University of Belgrade, Belgrade, Serbia; Clinic of Allergology and Immunology, University Clinical Center of Serbia, Belgrade, Serbia., Skrgat S; Department of Pulmonary Diseases and Allergy, University Medical Centre Ljubljana, Ljubljana, Slovenia; Medical Faculty, University of Ljubljana, Ljubljana, Slovenia., Kopac P; Medical Faculty, University of Ljubljana, Ljubljana, Slovenia; University Clinic of Respiratory and Allergic Diseases Golnik, Golnik, Slovenia., Ramos-Barbon D; Hospital de la Santa Creu i Sant Pau and Biomedical Research Institute Sant Pau, Barcelona, Spain., Pérez de Llano L; Servicio de Neumología, University Hospital Lucus Augusti, EOXI Lugo, Monteforte, Cervo, Spain., Garcia VL; Evidenze Clinical Research, Madrid, Spain., Morenos Martos D; Evidenze Clinical Research, Madrid, Spain., Dahlén B; Clinical Lung- and Allergy Research Unit, Department of Medicine Huddinge, Karolinska Institutet, Stockholm, Sweden; Department of Respiratory Medicine and Allergy, Severe Asthma Center, Karolinska University Hospital Huddinge, Stockholm, Sweden., Yasinska V; Clinical Lung- and Allergy Research Unit, Department of Medicine Huddinge, Karolinska Institutet, Stockholm, Sweden; Karolinska Severe Asthma Center, Department of Respiratory Medicine and Allergy, Karolinska University Hospital, Stockholm, Sweden., Tenselius O; Department of Respiratory Medicine and Allergy, Karolinska University Hospital, Stockholm, Sweden., Janson C; Department of Medical Sciences, Respiratory, Allergy and Sleep Research, Uppsala University, Sweden., Egesten A; Department of Clinical Sciences Lund, Respiratory Medicine, Allergology and Palliative Medicine, Lund University and Skåne University Hospital, Lund, Sweden., Richter J; Department of Clinical Sciences Lund, Respiratory Medicine, Allergology and Palliative Medicine, Lund University and Skåne University Hospital, Lund, Sweden., Emilsson ÖI; Department of Medical Sciences, Respiratory, Allergy and Sleep Research, Uppsala University, Sweden; Faculty of Medicine, University of Iceland, Reykjavík, Iceland., Leuppi J; University Institute of Internal Medicine, Cantonal Hospital Baselland, Liestal, Switzerland; Faculty of Medicine, University of Basel, Basel, Switzerland., Gemicioglu B; Department of Pulmonary Diseases, Cerrahpasa Faculty of Medicine, Istanbul University-Cerrahpasa, Istanbul, Türkiye., Celik G; Division of Immunology and Allergy, Ankara University School of Medicine, Ankara, Türkiye., Damadoglu E; Department of Pulmonary Diseases, Division of Allergy and Clinical Immunology, Hacettepe University, Faculty of Medicine, Ankara, Türkiye., Goksel O; Department of Pulmonary Medicine, Head Division of Immunology and Allergy, Laboratory of Occupational and Environmental Respiratory Diseases and Asthma, Ege University, Faculty of Medicine, Izmir, Türkiye; EgeSAM-Ege University Translational Pulmonary Research Center, Izmir, Türkiye., Heaney L; Wellcome-Wolfson Institute for Experimental Medicine, Queen's University, Belfast, UK., Busby J; Centre for Public Health, School of Medicine, Dentistry and Biomedical Sciences, Queen's University, Belfast, UK., Redmond C; Wellcome-Wolfson Institute for Experimental Medicine, Queen's University, Belfast, UK., Masoli M; Respiratory Medicine, Royal Devon University Healthcare NHS Foundation, Exeter, UK., Chaudhuri R; Respiratory Medicine, Gartnavel General Hospital, Glasgow, UK; School of Infection and Immunity, University of Glasgow, Glasgow, UK., Dennison P; Respiratory Medicine, University Hospital Southampton NHS Foundation Trust, Southampton, UK., Doe S; Newcastle upon Tyne Hospitals NHS Foundation Trust, Newcastle, UK., Kurukulaaratchy R; Respiratory Medicine, University Hospital Southampton NHS Foundation Trust, Southampton, UK; School of Clinical and Experimental Sciences, Faculty of Medicine, University of Southampton, Southampton, UK; National Institute for Health Research (NIHR) Southampton Biomedical Research Centre at University Hospital Southampton NHS Foundation Trust, Southampton, UK; The David Hide Asthma and Allergy Research Centre, St Mary's Hospital, Newport, Isle of Wight, UK., Bel E; Department of Respiratory Medicine, Amsterdam UMC, University of Amsterdam, Amsterdam, Netherlands., Djukanovic R; School of Clinical and Experimental Sciences, Faculty of Medicine, University of Southampton, Southampton, UK; National Institute for Health Research (NIHR) Southampton Biomedical Research Centre at University Hospital Southampton NHS Foundation Trust, Southampton, UK., Bourdin A; PhyMedExp, (INSERM U 1046, CNRS UMR9214), Montpellier University, Montpellier, France; Department of Respiratory Diseases, Montpellier University Hospital, Arnaud de Villeneuve Hospital, Montpellier, France., Ten Brinke A; Department of Pulmonology, Frisius Medical Center, Leeuwarden, Netherlands., Schleich F; Department of Pneumology-Allergology, CHU of Liège, Liége, Belgium; GIGAI(3), Pneumology Research Group, Liège University, Liège, Belgium; Exercise Physiology Lab, Department of Physical Activity and Rehabilitation Sciences, University of Liège, Liège, Belgium., Porsbjerg C; Department of Respiratory Medicine and Infectious Diseases - Bispebjerg, Copenhagen University Hospital, Copenhagen, Denmark., Bossios A; Division for Lung and Airway Research, Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden; Lung Laboratory, Center for Molecular Medicine, Karolinska University Hospital, Stockholm, Sweden; Karolinska Severe Asthma Center, Department of Respiratory Medicine and Allergy, Karolinska University Hospital, Stockholm, Sweden. Electronic address: apostolos.bossios@ki.se.
Source: The Lancet. Respiratory medicine [Lancet Respir Med] 2026 Jun 24. Date of Electronic Publication: 2026 Jun 24.
Publication Type: Journal Article
Journal Info: Publisher: Elsevier Country of Publication: England NLM ID: 101605555 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2213-2619 (Electronic) Linking ISSN: 22132600 NLM ISO Abbreviation: Lancet Respir Med Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:2213-2619
DOI:10.1016/S2213-2600(26)00141-4