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Urban particulate matter impairs human epidermal keratinocyte biology via the TRPV1-mitochondrial axis and TRPV1-Notch signaling.

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Title: Urban particulate matter impairs human epidermal keratinocyte biology via the TRPV1-mitochondrial axis and TRPV1-Notch signaling.
Authors: Kwon K; Molecular Dermatology Laboratory, Department of Integrative Biotechnology, College of Biotechnology and Bioengineering, Sungkyunkwan University, Suwon City, Gyunggi Do 16419, Korea., Kim G; Molecular Dermatology Laboratory, Department of Integrative Biotechnology, College of Biotechnology and Bioengineering, Sungkyunkwan University, Suwon City, Gyunggi Do 16419, Korea; Department of Metabiohealth, Institute for Cross-disciplinary Studies, Sungkyunkwan University, Suwon City, Gyunggi Do 16419, Korea., Oh SW; Molecular Dermatology Laboratory, Department of Integrative Biotechnology, College of Biotechnology and Bioengineering, Sungkyunkwan University, Suwon City, Gyunggi Do 16419, Korea., Yu E; Molecular Dermatology Laboratory, Department of Integrative Biotechnology, College of Biotechnology and Bioengineering, Sungkyunkwan University, Suwon City, Gyunggi Do 16419, Korea., Shin HS; Molecular Dermatology Laboratory, Department of Integrative Biotechnology, College of Biotechnology and Bioengineering, Sungkyunkwan University, Suwon City, Gyunggi Do 16419, Korea., Min S; Molecular Dermatology Laboratory, Department of Integrative Biotechnology, College of Biotechnology and Bioengineering, Sungkyunkwan University, Suwon City, Gyunggi Do 16419, Korea., Kim Y; Molecular Dermatology Laboratory, Department of Integrative Biotechnology, College of Biotechnology and Bioengineering, Sungkyunkwan University, Suwon City, Gyunggi Do 16419, Korea., Bin Lee S; Molecular Dermatology Laboratory, Department of Integrative Biotechnology, College of Biotechnology and Bioengineering, Sungkyunkwan University, Suwon City, Gyunggi Do 16419, Korea., Jung E; Biospectrum Life Science Institute, Seongnam City, Gyunggi Do 13216, Korea., Cho JY; Molecular Immunology Laboratory, Department of Integrative Biotechnology, College of Biotechnology and Bioengineering, Sungkyunkwan University, Suwon City, Gyunggi Do 16419, Korea. Electronic address: jaecho@skku.edu., Lee J; Molecular Dermatology Laboratory, Department of Integrative Biotechnology, College of Biotechnology and Bioengineering, Sungkyunkwan University, Suwon City, Gyunggi Do 16419, Korea. Electronic address: bioneer@skku.edu.
Source: Environmental toxicology and pharmacology [Environ Toxicol Pharmacol] 2026 Aug; Vol. 125, pp. 105084. Date of Electronic Publication: 2026 Jun 24.
Publication Type: Journal Article
Journal Info: Publisher: Elsevier Science B.V Country of Publication: Netherlands NLM ID: 9612020 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1872-7077 (Electronic) Linking ISSN: 13826689 NLM ISO Abbreviation: Environ Toxicol Pharmacol Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Urban particulate matter impairs human epidermal keratinocyte biology via the TRPV1-mitochondrial axis and TRPV1-Notch signaling.
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  Data: <searchLink fieldCode="AU" term="%22Kwon+K%22">Kwon K</searchLink>; Molecular Dermatology Laboratory, Department of Integrative Biotechnology, College of Biotechnology and Bioengineering, Sungkyunkwan University, Suwon City, Gyunggi Do 16419, Korea.<br /><searchLink fieldCode="AU" term="%22Kim+G%22">Kim G</searchLink>; Molecular Dermatology Laboratory, Department of Integrative Biotechnology, College of Biotechnology and Bioengineering, Sungkyunkwan University, Suwon City, Gyunggi Do 16419, Korea; Department of Metabiohealth, Institute for Cross-disciplinary Studies, Sungkyunkwan University, Suwon City, Gyunggi Do 16419, Korea.<br /><searchLink fieldCode="AU" term="%22Oh+SW%22">Oh SW</searchLink>; Molecular Dermatology Laboratory, Department of Integrative Biotechnology, College of Biotechnology and Bioengineering, Sungkyunkwan University, Suwon City, Gyunggi Do 16419, Korea.<br /><searchLink fieldCode="AU" term="%22Yu+E%22">Yu E</searchLink>; Molecular Dermatology Laboratory, Department of Integrative Biotechnology, College of Biotechnology and Bioengineering, Sungkyunkwan University, Suwon City, Gyunggi Do 16419, Korea.<br /><searchLink fieldCode="AU" term="%22Shin+HS%22">Shin HS</searchLink>; Molecular Dermatology Laboratory, Department of Integrative Biotechnology, College of Biotechnology and Bioengineering, Sungkyunkwan University, Suwon City, Gyunggi Do 16419, Korea.<br /><searchLink fieldCode="AU" term="%22Min+S%22">Min S</searchLink>; Molecular Dermatology Laboratory, Department of Integrative Biotechnology, College of Biotechnology and Bioengineering, Sungkyunkwan University, Suwon City, Gyunggi Do 16419, Korea.<br /><searchLink fieldCode="AU" term="%22Kim+Y%22">Kim Y</searchLink>; Molecular Dermatology Laboratory, Department of Integrative Biotechnology, College of Biotechnology and Bioengineering, Sungkyunkwan University, Suwon City, Gyunggi Do 16419, Korea.<br /><searchLink fieldCode="AU" term="%22Bin+Lee+S%22">Bin Lee S</searchLink>; Molecular Dermatology Laboratory, Department of Integrative Biotechnology, College of Biotechnology and Bioengineering, Sungkyunkwan University, Suwon City, Gyunggi Do 16419, Korea.<br /><searchLink fieldCode="AU" term="%22Jung+E%22">Jung E</searchLink>; Biospectrum Life Science Institute, Seongnam City, Gyunggi Do 13216, Korea.<br /><searchLink fieldCode="AU" term="%22Cho+JY%22">Cho JY</searchLink>; Molecular Immunology Laboratory, Department of Integrative Biotechnology, College of Biotechnology and Bioengineering, Sungkyunkwan University, Suwon City, Gyunggi Do 16419, Korea. Electronic address: jaecho@skku.edu.<br /><searchLink fieldCode="AU" term="%22Lee+J%22">Lee J</searchLink>; Molecular Dermatology Laboratory, Department of Integrative Biotechnology, College of Biotechnology and Bioengineering, Sungkyunkwan University, Suwon City, Gyunggi Do 16419, Korea. Electronic address: bioneer@skku.edu.
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  Data: <searchLink fieldCode="JN" term="%229612020%22">Environmental toxicology and pharmacology</searchLink> [Environ Toxicol Pharmacol] 2026 Aug; Vol. 125, pp. 105084. <i>Date of Electronic Publication: </i>2026 Jun 24.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Elsevier+Science+B%2EV%22">Elsevier Science B.V </searchLink><i>Country of Publication: </i>Netherlands <i>NLM ID: </i>9612020 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1872-7077 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2213826689%22">13826689 </searchLink><i>NLM ISO Abbreviation: </i>Environ Toxicol Pharmacol <i>Subsets: </i>MEDLINE
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              Text: 2026 Aug
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