Quantitative trait loci mapping of gene expression and chromatin accessibility in primary fibroblasts reveals shared allelic effects between Latin American and European ancestries.

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Title: Quantitative trait loci mapping of gene expression and chromatin accessibility in primary fibroblasts reveals shared allelic effects between Latin American and European ancestries.
Authors: Boltz TA; Department of Human Genetics, David Geffen School of Medicine, UCLA, Los Angeles, CA, USA. tboltz@broadinstitute.org., Bot M; Center for Neurobehavioral Genetics, Semel Institute for Neuroscience and Human Behavior, UCLA, Los Angeles, CA, USA., Lapinska S; Graduate Group in Computational Biology, University of Pennsylvania, Philadelphia, PA, USA., Schwarz T; Department of Bioinformatics, David Geffen School of Medicine, UCLA, Los Angeles, CA, USA., Hou K; Department of Bioinformatics, David Geffen School of Medicine, UCLA, Los Angeles, CA, USA., Garske KM; Department of Human Genetics, David Geffen School of Medicine, UCLA, Los Angeles, CA, USA., Freund MK; Department of Human Genetics, David Geffen School of Medicine, UCLA, Los Angeles, CA, USA., Bearden CE; Center for Neurobehavioral Genetics, Semel Institute for Neuroscience and Human Behavior, UCLA, Los Angeles, CA, USA.; Department of Psychology, UCLA, Los Angeles, CA, USA., Macaya G; Center for Research in Cellular and Molecular Biology, Universidad de Costa Rica, San José, Costa Rica., Lopez-Jaramillo C; Department of Psychiatry, University of Antioquia, Medellín, Antioquia, Colombia., Freimer N; Center for Neurobehavioral Genetics, Semel Institute for Neuroscience and Human Behavior, UCLA, Los Angeles, CA, USA., Boks MP; Department of Psychiatry, Amsterdam UMC, Amsterdam, The Netherlands.; Dimence Group, Dimence Institute for Specialized Mental Health Care, Deventer, The Netherlands.; Department of Psychiatry, Brain Center University Medical Center Utrecht, University Utrecht, Utrecht, the Netherlands., Kahn RS; Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Pasaniuc B; Department of Genetics, University of Pennsylvania, Philadelphia, PA, USA., Ophoff RA; Department of Human Genetics, David Geffen School of Medicine, UCLA, Los Angeles, CA, USA. ophoff@g.ucla.edu.; Center for Neurobehavioral Genetics, Semel Institute for Neuroscience and Human Behavior, UCLA, Los Angeles, CA, USA. ophoff@g.ucla.edu.
Source: BMC genomics [BMC Genomics] 2026 Jun 24. Date of Electronic Publication: 2026 Jun 24.
Publication Type: Journal Article
Journal Info: Publisher: BioMed Central Country of Publication: England NLM ID: 100965258 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1471-2164 (Electronic) Linking ISSN: 14712164 NLM ISO Abbreviation: BMC Genomics Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1471-2164
DOI:10.1186/s12864-026-13065-3