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Quantitative trait loci mapping of gene expression and chromatin accessibility in primary fibroblasts reveals shared allelic effects between Latin American and European ancestries.

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Title: Quantitative trait loci mapping of gene expression and chromatin accessibility in primary fibroblasts reveals shared allelic effects between Latin American and European ancestries.
Authors: Boltz TA; Department of Human Genetics, David Geffen School of Medicine, UCLA, Los Angeles, CA, USA. tboltz@broadinstitute.org., Bot M; Center for Neurobehavioral Genetics, Semel Institute for Neuroscience and Human Behavior, UCLA, Los Angeles, CA, USA., Lapinska S; Graduate Group in Computational Biology, University of Pennsylvania, Philadelphia, PA, USA., Schwarz T; Department of Bioinformatics, David Geffen School of Medicine, UCLA, Los Angeles, CA, USA., Hou K; Department of Bioinformatics, David Geffen School of Medicine, UCLA, Los Angeles, CA, USA., Garske KM; Department of Human Genetics, David Geffen School of Medicine, UCLA, Los Angeles, CA, USA., Freund MK; Department of Human Genetics, David Geffen School of Medicine, UCLA, Los Angeles, CA, USA., Bearden CE; Center for Neurobehavioral Genetics, Semel Institute for Neuroscience and Human Behavior, UCLA, Los Angeles, CA, USA.; Department of Psychology, UCLA, Los Angeles, CA, USA., Macaya G; Center for Research in Cellular and Molecular Biology, Universidad de Costa Rica, San José, Costa Rica., Lopez-Jaramillo C; Department of Psychiatry, University of Antioquia, Medellín, Antioquia, Colombia., Freimer N; Center for Neurobehavioral Genetics, Semel Institute for Neuroscience and Human Behavior, UCLA, Los Angeles, CA, USA., Boks MP; Department of Psychiatry, Amsterdam UMC, Amsterdam, The Netherlands.; Dimence Group, Dimence Institute for Specialized Mental Health Care, Deventer, The Netherlands.; Department of Psychiatry, Brain Center University Medical Center Utrecht, University Utrecht, Utrecht, the Netherlands., Kahn RS; Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Pasaniuc B; Department of Genetics, University of Pennsylvania, Philadelphia, PA, USA., Ophoff RA; Department of Human Genetics, David Geffen School of Medicine, UCLA, Los Angeles, CA, USA. ophoff@g.ucla.edu.; Center for Neurobehavioral Genetics, Semel Institute for Neuroscience and Human Behavior, UCLA, Los Angeles, CA, USA. ophoff@g.ucla.edu.
Source: BMC genomics [BMC Genomics] 2026 Jun 24. Date of Electronic Publication: 2026 Jun 24.
Publication Type: Journal Article
Journal Info: Publisher: BioMed Central Country of Publication: England NLM ID: 100965258 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1471-2164 (Electronic) Linking ISSN: 14712164 NLM ISO Abbreviation: BMC Genomics Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Quantitative trait loci mapping of gene expression and chromatin accessibility in primary fibroblasts reveals shared allelic effects between Latin American and European ancestries.
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  Data: <searchLink fieldCode="AU" term="%22Boltz+TA%22">Boltz TA</searchLink>; Department of Human Genetics, David Geffen School of Medicine, UCLA, Los Angeles, CA, USA. tboltz@broadinstitute.org.<br /><searchLink fieldCode="AU" term="%22Bot+M%22">Bot M</searchLink>; Center for Neurobehavioral Genetics, Semel Institute for Neuroscience and Human Behavior, UCLA, Los Angeles, CA, USA.<br /><searchLink fieldCode="AU" term="%22Lapinska+S%22">Lapinska S</searchLink>; Graduate Group in Computational Biology, University of Pennsylvania, Philadelphia, PA, USA.<br /><searchLink fieldCode="AU" term="%22Schwarz+T%22">Schwarz T</searchLink>; Department of Bioinformatics, David Geffen School of Medicine, UCLA, Los Angeles, CA, USA.<br /><searchLink fieldCode="AU" term="%22Hou+K%22">Hou K</searchLink>; Department of Bioinformatics, David Geffen School of Medicine, UCLA, Los Angeles, CA, USA.<br /><searchLink fieldCode="AU" term="%22Garske+KM%22">Garske KM</searchLink>; Department of Human Genetics, David Geffen School of Medicine, UCLA, Los Angeles, CA, USA.<br /><searchLink fieldCode="AU" term="%22Freund+MK%22">Freund MK</searchLink>; Department of Human Genetics, David Geffen School of Medicine, UCLA, Los Angeles, CA, USA.<br /><searchLink fieldCode="AU" term="%22Bearden+CE%22">Bearden CE</searchLink>; Center for Neurobehavioral Genetics, Semel Institute for Neuroscience and Human Behavior, UCLA, Los Angeles, CA, USA.; Department of Psychology, UCLA, Los Angeles, CA, USA.<br /><searchLink fieldCode="AU" term="%22Macaya+G%22">Macaya G</searchLink>; Center for Research in Cellular and Molecular Biology, Universidad de Costa Rica, San José, Costa Rica.<br /><searchLink fieldCode="AU" term="%22Lopez-Jaramillo+C%22">Lopez-Jaramillo C</searchLink>; Department of Psychiatry, University of Antioquia, Medellín, Antioquia, Colombia.<br /><searchLink fieldCode="AU" term="%22Freimer+N%22">Freimer N</searchLink>; Center for Neurobehavioral Genetics, Semel Institute for Neuroscience and Human Behavior, UCLA, Los Angeles, CA, USA.<br /><searchLink fieldCode="AU" term="%22Boks+MP%22">Boks MP</searchLink>; Department of Psychiatry, Amsterdam UMC, Amsterdam, The Netherlands.; Dimence Group, Dimence Institute for Specialized Mental Health Care, Deventer, The Netherlands.; Department of Psychiatry, Brain Center University Medical Center Utrecht, University Utrecht, Utrecht, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Kahn+RS%22">Kahn RS</searchLink>; Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Pasaniuc+B%22">Pasaniuc B</searchLink>; Department of Genetics, University of Pennsylvania, Philadelphia, PA, USA.<br /><searchLink fieldCode="AU" term="%22Ophoff+RA%22">Ophoff RA</searchLink>; Department of Human Genetics, David Geffen School of Medicine, UCLA, Los Angeles, CA, USA. ophoff@g.ucla.edu.; Center for Neurobehavioral Genetics, Semel Institute for Neuroscience and Human Behavior, UCLA, Los Angeles, CA, USA. ophoff@g.ucla.edu.
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              Text: 2026 Jun 24
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