Studying Early Life Live-Attenuated influenza virus immune Responses (STELLAR): study protocol for an exploratory observational study of the nasal mucosal and systemic immune response in healthy children given an intranasal live-attenuated influenza vaccine.

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Title: Studying Early Life Live-Attenuated influenza virus immune Responses (STELLAR): study protocol for an exploratory observational study of the nasal mucosal and systemic immune response in healthy children given an intranasal live-attenuated influenza vaccine.
Authors: Kelleher K; Oxford Vaccine Group, Department of Paediatrics, University of Oxford, Oxford, UK., Bennett R; Oxford Vaccine Group, Department of Paediatrics, University of Oxford, Oxford, UK., Jackson R; Oxford Vaccine Group, Department of Paediatrics, University of Oxford, Oxford, UK., Ivaska L; Oxford Vaccine Group, Department of Paediatrics, University of Oxford, Oxford, UK., Singh N; Oxford Vaccine Group, Department of Paediatrics, University of Oxford, Oxford, UK., Quintero Barceinas RS; Oxford Vaccine Group, Department of Paediatrics, University of Oxford, Oxford, UK., Plested E; Oxford Vaccine Group, Department of Paediatrics, University of Oxford, Oxford, UK., Francis E; Oxford Vaccine Group, Department of Paediatrics, University of Oxford, Oxford, UK., Mujadidi YF; Oxford Vaccine Group, Department of Paediatrics, University of Oxford, Oxford, UK., Nwankwo C; Oxford Vaccine Group, Department of Paediatrics, University of Oxford, Oxford, UK., Francis-Hill J; Oxford Vaccine Group, Department of Paediatrics, University of Oxford, Oxford, UK., Thompson A; Oxford Vaccine Group, Department of Paediatrics, University of Oxford, Oxford, UK., Solórzano C; Oxford Vaccine Group, Department of Paediatrics, University of Oxford, Oxford, UK., Baughan H; Oxford Vaccine Group, Department of Paediatrics, University of Oxford, Oxford, UK., Liu X; Oxford Vaccine Group, Department of Paediatrics, University of Oxford, Oxford, UK., Didierlaurent AM; Center of Vaccinology, Department of Pathology and Immunology, University of Geneva, Geneva, GE, Switzerland., Urban BC; Oxford Vaccine Group, Department of Paediatrics, University of Oxford, Oxford, UK., Ferreira DM; Oxford Vaccine Group, Department of Paediatrics, University of Oxford, Oxford, UK daniela.ferreira@paediatrics.ox.ac.uk., Kelly D; Oxford Vaccine Group, Department of Paediatrics, University of Oxford, Oxford, UK.
Source: BMJ open [BMJ Open] 2026 Jun 25; Vol. 16 (6), pp. e114107. Date of Electronic Publication: 2026 Jun 25.
Publication Type: Clinical Trial Protocol; Journal Article
Journal Info: Publisher: BMJ Publishing Group Ltd Country of Publication: England NLM ID: 101552874 Publication Model: Electronic Cited Medium: Internet ISSN: 2044-6055 (Electronic) Linking ISSN: 20446055 NLM ISO Abbreviation: BMJ Open Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:2044-6055
DOI:10.1136/bmjopen-2025-114107