Metformin Enhances 2-Aminoethyl Dihydrogen Phosphate-Induced Mitochondrial Dysfunction and Apoptosis in Melanoma Cells.

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Title: Metformin Enhances 2-Aminoethyl Dihydrogen Phosphate-Induced Mitochondrial Dysfunction and Apoptosis in Melanoma Cells.
Authors: Oliveira TAD; Graduate Program in Anatomy of Domestic and Wild Animals, School of Veterinary Medicine and Animal Science, University of São Paulo, São Paulo 05508-270, Brazil.; Development and Innovation Laboratory, Butantan Institute, São Paulo 05503-900, Brazil., Almeida GHDR; Development and Innovation Laboratory, Butantan Institute, São Paulo 05503-900, Brazil., Chammas SM; Development and Innovation Laboratory, Butantan Institute, São Paulo 05503-900, Brazil., Laiso RAN; Graduate Program in Anatomy of Domestic and Wild Animals, School of Veterinary Medicine and Animal Science, University of São Paulo, São Paulo 05508-270, Brazil.; Development and Innovation Laboratory, Butantan Institute, São Paulo 05503-900, Brazil., Sousa YEM; Development and Innovation Laboratory, Butantan Institute, São Paulo 05503-900, Brazil., Matos ÍGTP; Development and Innovation Laboratory, Butantan Institute, São Paulo 05503-900, Brazil., Rodriguez VS; Development and Innovation Laboratory, Butantan Institute, São Paulo 05503-900, Brazil., Queiroz BCB; Development and Innovation Laboratory, Butantan Institute, São Paulo 05503-900, Brazil., Oliveira ACA; Development and Innovation Laboratory, Butantan Institute, São Paulo 05503-900, Brazil., de Lima S; Development and Innovation Laboratory, Butantan Institute, São Paulo 05503-900, Brazil., Arruda LAM; Development and Innovation Laboratory, Butantan Institute, São Paulo 05503-900, Brazil., Rabelo DDC; Graduate Program in Anatomy of Domestic and Wild Animals, School of Veterinary Medicine and Animal Science, University of São Paulo, São Paulo 05508-270, Brazil., Rici REG; Graduate Program in Anatomy of Domestic and Wild Animals, School of Veterinary Medicine and Animal Science, University of São Paulo, São Paulo 05508-270, Brazil., Mathias PCF; Graduate Program in Biological Sciences, State University of Maringá, Maringá 87020-900, Brazil.; Multidisciplinary Institute of Health, Federal University of Bahia, Vitória da Conquista 45029-094, Brazil., Maria DA; Graduate Program in Anatomy of Domestic and Wild Animals, School of Veterinary Medicine and Animal Science, University of São Paulo, São Paulo 05508-270, Brazil.; Development and Innovation Laboratory, Butantan Institute, São Paulo 05503-900, Brazil.
Source: International journal of molecular sciences [Int J Mol Sci] 2026 Jun 18; Vol. 27 (12). Date of Electronic Publication: 2026 Jun 18.
Publication Type: Journal Article
Journal Info: Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067 (Electronic) Linking ISSN: 14220067 NLM ISO Abbreviation: Int J Mol Sci Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:1422-0067
DOI:10.3390/ijms27125493