Intranasal Immunization with Recombinant Hemagglutinin of Influenza A/H5 Virus Complexed with Novochizol Induces Virus-Neutralizing Antibodies and Protects Animals from Lethal Viral Challenge.
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| Title: | Intranasal Immunization with Recombinant Hemagglutinin of Influenza A/H5 Virus Complexed with Novochizol Induces Virus-Neutralizing Antibodies and Protects Animals from Lethal Viral Challenge. |
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| Authors: | Rudometova NB; State Research Center of Virology and Biotechnology 'Vector', Rospotrebnadzor, 630559 Koltsovo, Russia., Ivanova KI; State Research Center of Virology and Biotechnology 'Vector', Rospotrebnadzor, 630559 Koltsovo, Russia., Fomenko VV; N.N. Vorozhtsov Novosibirsk Institute of Organic Chemistry of the Siberian Branch of the Russian Academy of Sciences, 630090 Novosibirsk, Russia., Rudometov AP; State Research Center of Virology and Biotechnology 'Vector', Rospotrebnadzor, 630559 Koltsovo, Russia., Kisakova LA; State Research Center of Virology and Biotechnology 'Vector', Rospotrebnadzor, 630559 Koltsovo, Russia., Kisakov DN; State Research Center of Virology and Biotechnology 'Vector', Rospotrebnadzor, 630559 Koltsovo, Russia., Yakovleva EV; State Research Center of Virology and Biotechnology 'Vector', Rospotrebnadzor, 630559 Koltsovo, Russia., Yakovlev VA; State Research Center of Virology and Biotechnology 'Vector', Rospotrebnadzor, 630559 Koltsovo, Russia., Makarova KP; State Research Center of Virology and Biotechnology 'Vector', Rospotrebnadzor, 630559 Koltsovo, Russia., Vakhitov DI; State Research Center of Virology and Biotechnology 'Vector', Rospotrebnadzor, 630559 Koltsovo, Russia., Borgoyakova MB; State Research Center of Virology and Biotechnology 'Vector', Rospotrebnadzor, 630559 Koltsovo, Russia., Starostina EV; State Research Center of Virology and Biotechnology 'Vector', Rospotrebnadzor, 630559 Koltsovo, Russia., Zaitsev BN; State Research Center of Virology and Biotechnology 'Vector', Rospotrebnadzor, 630559 Koltsovo, Russia., Litvinova VR; State Research Center of Virology and Biotechnology 'Vector', Rospotrebnadzor, 630559 Koltsovo, Russia., Pyankov SA; State Research Center of Virology and Biotechnology 'Vector', Rospotrebnadzor, 630559 Koltsovo, Russia., Ilyicheva TN; State Research Center of Virology and Biotechnology 'Vector', Rospotrebnadzor, 630559 Koltsovo, Russia., Ilyichev AA; State Research Center of Virology and Biotechnology 'Vector', Rospotrebnadzor, 630559 Koltsovo, Russia., Gudymo AS; State Research Center of Virology and Biotechnology 'Vector', Rospotrebnadzor, 630559 Koltsovo, Russia., Marchenko VY; State Research Center of Virology and Biotechnology 'Vector', Rospotrebnadzor, 630559 Koltsovo, Russia., Salakhutdinov NF; N.N. Vorozhtsov Novosibirsk Institute of Organic Chemistry of the Siberian Branch of the Russian Academy of Sciences, 630090 Novosibirsk, Russia., Agafonov AP; State Research Center of Virology and Biotechnology 'Vector', Rospotrebnadzor, 630559 Koltsovo, Russia., Karpenko LI; State Research Center of Virology and Biotechnology 'Vector', Rospotrebnadzor, 630559 Koltsovo, Russia. |
| Source: | Pharmaceutics [Pharmaceutics] 2026 May 28; Vol. 18 (6). Date of Electronic Publication: 2026 May 28. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: MDPI Country of Publication: Switzerland NLM ID: 101534003 Publication Model: Electronic Cited Medium: Print ISSN: 1999-4923 (Print) Linking ISSN: 19994923 NLM ISO Abbreviation: Pharmaceutics Subsets: PubMed not MEDLINE |
| Database: | MEDLINE Ultimate |
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| Header | DbId: mdl DbLabel: MEDLINE Ultimate An: 42357285 AccessLevel: 2 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: Intranasal Immunization with Recombinant Hemagglutinin of Influenza A/H5 Virus Complexed with Novochizol Induces Virus-Neutralizing Antibodies and Protects Animals from Lethal Viral Challenge. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AU" term="%22Rudometova+NB%22">Rudometova NB</searchLink>; State Research Center of Virology and Biotechnology 'Vector', Rospotrebnadzor, 630559 Koltsovo, Russia.<br /><searchLink fieldCode="AU" term="%22Ivanova+KI%22">Ivanova KI</searchLink>; State Research Center of Virology and Biotechnology 'Vector', Rospotrebnadzor, 630559 Koltsovo, Russia.<br /><searchLink fieldCode="AU" term="%22Fomenko+VV%22">Fomenko VV</searchLink>; N.N. Vorozhtsov Novosibirsk Institute of Organic Chemistry of the Siberian Branch of the Russian Academy of Sciences, 630090 Novosibirsk, Russia.<br /><searchLink fieldCode="AU" term="%22Rudometov+AP%22">Rudometov AP</searchLink>; State Research Center of Virology and Biotechnology 'Vector', Rospotrebnadzor, 630559 Koltsovo, Russia.<br /><searchLink fieldCode="AU" term="%22Kisakova+LA%22">Kisakova LA</searchLink>; State Research Center of Virology and Biotechnology 'Vector', Rospotrebnadzor, 630559 Koltsovo, Russia.<br /><searchLink fieldCode="AU" term="%22Kisakov+DN%22">Kisakov DN</searchLink>; State Research Center of Virology and Biotechnology 'Vector', Rospotrebnadzor, 630559 Koltsovo, Russia.<br /><searchLink fieldCode="AU" term="%22Yakovleva+EV%22">Yakovleva EV</searchLink>; State Research Center of Virology and Biotechnology 'Vector', Rospotrebnadzor, 630559 Koltsovo, Russia.<br /><searchLink fieldCode="AU" term="%22Yakovlev+VA%22">Yakovlev VA</searchLink>; State Research Center of Virology and Biotechnology 'Vector', Rospotrebnadzor, 630559 Koltsovo, Russia.<br /><searchLink fieldCode="AU" term="%22Makarova+KP%22">Makarova KP</searchLink>; State Research Center of Virology and Biotechnology 'Vector', Rospotrebnadzor, 630559 Koltsovo, Russia.<br /><searchLink fieldCode="AU" term="%22Vakhitov+DI%22">Vakhitov DI</searchLink>; State Research Center of Virology and Biotechnology 'Vector', Rospotrebnadzor, 630559 Koltsovo, Russia.<br /><searchLink fieldCode="AU" term="%22Borgoyakova+MB%22">Borgoyakova MB</searchLink>; State Research Center of Virology and Biotechnology 'Vector', Rospotrebnadzor, 630559 Koltsovo, Russia.<br /><searchLink fieldCode="AU" term="%22Starostina+EV%22">Starostina EV</searchLink>; State Research Center of Virology and Biotechnology 'Vector', Rospotrebnadzor, 630559 Koltsovo, Russia.<br /><searchLink fieldCode="AU" term="%22Zaitsev+BN%22">Zaitsev BN</searchLink>; State Research Center of Virology and Biotechnology 'Vector', Rospotrebnadzor, 630559 Koltsovo, Russia.<br /><searchLink fieldCode="AU" term="%22Litvinova+VR%22">Litvinova VR</searchLink>; State Research Center of Virology and Biotechnology 'Vector', Rospotrebnadzor, 630559 Koltsovo, Russia.<br /><searchLink fieldCode="AU" term="%22Pyankov+SA%22">Pyankov SA</searchLink>; State Research Center of Virology and Biotechnology 'Vector', Rospotrebnadzor, 630559 Koltsovo, Russia.<br /><searchLink fieldCode="AU" term="%22Ilyicheva+TN%22">Ilyicheva TN</searchLink>; State Research Center of Virology and Biotechnology 'Vector', Rospotrebnadzor, 630559 Koltsovo, Russia.<br /><searchLink fieldCode="AU" term="%22Ilyichev+AA%22">Ilyichev AA</searchLink>; State Research Center of Virology and Biotechnology 'Vector', Rospotrebnadzor, 630559 Koltsovo, Russia.<br /><searchLink fieldCode="AU" term="%22Gudymo+AS%22">Gudymo AS</searchLink>; State Research Center of Virology and Biotechnology 'Vector', Rospotrebnadzor, 630559 Koltsovo, Russia.<br /><searchLink fieldCode="AU" term="%22Marchenko+VY%22">Marchenko VY</searchLink>; State Research Center of Virology and Biotechnology 'Vector', Rospotrebnadzor, 630559 Koltsovo, Russia.<br /><searchLink fieldCode="AU" term="%22Salakhutdinov+NF%22">Salakhutdinov NF</searchLink>; N.N. Vorozhtsov Novosibirsk Institute of Organic Chemistry of the Siberian Branch of the Russian Academy of Sciences, 630090 Novosibirsk, Russia.<br /><searchLink fieldCode="AU" term="%22Agafonov+AP%22">Agafonov AP</searchLink>; State Research Center of Virology and Biotechnology 'Vector', Rospotrebnadzor, 630559 Koltsovo, Russia.<br /><searchLink fieldCode="AU" term="%22Karpenko+LI%22">Karpenko LI</searchLink>; State Research Center of Virology and Biotechnology 'Vector', Rospotrebnadzor, 630559 Koltsovo, Russia. – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%22101534003%22">Pharmaceutics</searchLink> [Pharmaceutics] 2026 May 28; Vol. 18 (6). <i>Date of Electronic Publication: </i>2026 May 28. – Name: TypePub Label: Publication Type Group: TypPub Data: Journal Article – Name: TitleSource Label: Journal Info Group: Src Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22MDPI%22">MDPI </searchLink><i>Country of Publication: </i>Switzerland <i>NLM ID: </i>101534003 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Print <i>ISSN: </i>1999-4923 (Print) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2219994923%22">19994923 </searchLink><i>NLM ISO Abbreviation: </i>Pharmaceutics <i>Subsets: </i>PubMed not MEDLINE |
| PLink | https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=42357285 |
| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.3390/pharmaceutics18060669 Languages: – Code: eng Text: English Titles: – TitleFull: Intranasal Immunization with Recombinant Hemagglutinin of Influenza A/H5 Virus Complexed with Novochizol Induces Virus-Neutralizing Antibodies and Protects Animals from Lethal Viral Challenge. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Rudometova NB – PersonEntity: Name: NameFull: Ivanova KI – PersonEntity: Name: NameFull: Fomenko VV – PersonEntity: Name: NameFull: Rudometov AP – PersonEntity: Name: NameFull: Kisakova LA – PersonEntity: Name: NameFull: Kisakov DN – PersonEntity: Name: NameFull: Yakovleva EV – PersonEntity: Name: NameFull: Yakovlev VA – PersonEntity: Name: NameFull: Makarova KP – PersonEntity: Name: NameFull: Vakhitov DI – PersonEntity: Name: NameFull: Borgoyakova MB – PersonEntity: Name: NameFull: Starostina EV – PersonEntity: Name: NameFull: Zaitsev BN – PersonEntity: Name: NameFull: Litvinova VR – PersonEntity: Name: NameFull: Pyankov SA – PersonEntity: Name: NameFull: Ilyicheva TN – PersonEntity: Name: NameFull: Ilyichev AA – PersonEntity: Name: NameFull: Gudymo AS – PersonEntity: Name: NameFull: Marchenko VY – PersonEntity: Name: NameFull: Salakhutdinov NF – PersonEntity: Name: NameFull: Agafonov AP – PersonEntity: Name: NameFull: Karpenko LI IsPartOfRelationships: – BibEntity: Dates: – D: 28 M: 05 Text: 2026 May 28 Type: published Y: 2026 Identifiers: – Type: issn-print Value: 1999-4923 Numbering: – Type: volume Value: 18 – Type: issue Value: 6 Titles: – TitleFull: Pharmaceutics Type: main |
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