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A Sequence-Based Update on Amino Acid Substitutions in Influenza Polymerase Acidic Protein in Europe That Alter Baloxavir Susceptibility From 2009 to 2025.

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Title: A Sequence-Based Update on Amino Acid Substitutions in Influenza Polymerase Acidic Protein in Europe That Alter Baloxavir Susceptibility From 2009 to 2025.
Authors: Martín-Toribio A; National Influenza Centre, Valladolid, Spain.; Fundación Instituto de Estudios de Ciencias de la Salud de Castilla y León, Soria, Spain.; Microbiology Area, Faculty of Medicine, University of Valladolid, Spain., Inchausti-Moya I; Microbiology Section, Departamento de Ciencias, Farmacéuticas y de la Salud, Facultad de Farmacia, Universidad San Pablo-CEU, CEU Universities, Madrid, Spain.; Institute of Applied Molecular Medicine Nemesio Diez (IMMA-ND), Department of Basic Medical Sciences, Facultad de Medicina, Universidad San Pablo-CEU, CEU Universities, Boadilla del Monte, Spain., Toquero-Asensio M; National Influenza Centre, Valladolid, Spain.; Fundación Instituto de Estudios de Ciencias de la Salud de Castilla y León, Soria, Spain., García-Díaz S; National Influenza Centre, Valladolid, Spain.; Hospital Clínico Universitario de Valladolid, Valladolid, Spain., Sanchez-Martinez J; National Influenza Centre, Valladolid, Spain.; Fundación Instituto de Estudios de Ciencias de la Salud de Castilla y León, Soria, Spain., Rodriguez-Crespo C; National Influenza Centre, Valladolid, Spain.; Fundación Instituto de Estudios de Ciencias de la Salud de Castilla y León, Soria, Spain., Galindo-Carretero S; National Influenza Centre, Valladolid, Spain.; Fundación Instituto de Estudios de Ciencias de la Salud de Castilla y León, Soria, Spain., Iglesia-Aparicio R; National Influenza Centre, Valladolid, Spain.; Fundación Instituto de Estudios de Ciencias de la Salud de Castilla y León, Soria, Spain., Lopez-Gonzalo C; National Influenza Centre, Valladolid, Spain.; Fundación Instituto de Estudios de Ciencias de la Salud de Castilla y León, Soria, Spain., Antón-Contreras A; National Influenza Centre, Valladolid, Spain.; Fundación Instituto de Estudios de Ciencias de la Salud de Castilla y León, Soria, Spain., Rojo-Rello S; National Influenza Centre, Valladolid, Spain.; Microbiology Area, Faculty of Medicine, University of Valladolid, Spain.; Hospital Clínico Universitario de Valladolid, Valladolid, Spain., Dominguez-Gil M; National Influenza Centre, Valladolid, Spain.; Microbiology Area, Faculty of Medicine, University of Valladolid, Spain.; Hospital Universitario Rio Hortega, Valladolid, Spain., Hernández M; National Influenza Centre, Valladolid, Spain.; Microbiology Area, Faculty of Medicine, University of Valladolid, Spain., Eiros JM; National Influenza Centre, Valladolid, Spain.; Microbiology Area, Faculty of Medicine, University of Valladolid, Spain.; Hospital Clínico Universitario de Valladolid, Valladolid, Spain.; Hospital Universitario Rio Hortega, Valladolid, Spain.; Centro de Investigaciones Biomedicas en Red en Enfermedades Infecciosas (CIBERINFEC), Madrid, Spain., Nistal-Villan E; Microbiology Section, Departamento de Ciencias, Farmacéuticas y de la Salud, Facultad de Farmacia, Universidad San Pablo-CEU, CEU Universities, Madrid, Spain.; Institute of Applied Molecular Medicine Nemesio Diez (IMMA-ND), Department of Basic Medical Sciences, Facultad de Medicina, Universidad San Pablo-CEU, CEU Universities, Boadilla del Monte, Spain., Sanz-Muñoz I; National Influenza Centre, Valladolid, Spain.; Fundación Instituto de Estudios de Ciencias de la Salud de Castilla y León, Soria, Spain.; Centro de Investigaciones Biomedicas en Red en Enfermedades Infecciosas (CIBERINFEC), Madrid, Spain.
Source: Influenza and other respiratory viruses [Influenza Other Respir Viruses] 2026 Jul; Vol. 20 (7), pp. e70288.
Publication Type: Journal Article
Journal Info: Publisher: Wiley Country of Publication: England NLM ID: 101304007 Publication Model: Print Cited Medium: Internet ISSN: 1750-2659 (Electronic) Linking ISSN: 17502640 NLM ISO Abbreviation: Influenza Other Respir Viruses Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: A Sequence-Based Update on Amino Acid Substitutions in Influenza Polymerase Acidic Protein in Europe That Alter Baloxavir Susceptibility From 2009 to 2025.
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  Data: <searchLink fieldCode="AU" term="%22Martín-Toribio+A%22">Martín-Toribio A</searchLink>; National Influenza Centre, Valladolid, Spain.; Fundación Instituto de Estudios de Ciencias de la Salud de Castilla y León, Soria, Spain.; Microbiology Area, Faculty of Medicine, University of Valladolid, Spain.<br /><searchLink fieldCode="AU" term="%22Inchausti-Moya+I%22">Inchausti-Moya I</searchLink>; Microbiology Section, Departamento de Ciencias, Farmacéuticas y de la Salud, Facultad de Farmacia, Universidad San Pablo-CEU, CEU Universities, Madrid, Spain.; Institute of Applied Molecular Medicine Nemesio Diez (IMMA-ND), Department of Basic Medical Sciences, Facultad de Medicina, Universidad San Pablo-CEU, CEU Universities, Boadilla del Monte, Spain.<br /><searchLink fieldCode="AU" term="%22Toquero-Asensio+M%22">Toquero-Asensio M</searchLink>; National Influenza Centre, Valladolid, Spain.; Fundación Instituto de Estudios de Ciencias de la Salud de Castilla y León, Soria, Spain.<br /><searchLink fieldCode="AU" term="%22García-Díaz+S%22">García-Díaz S</searchLink>; National Influenza Centre, Valladolid, Spain.; Hospital Clínico Universitario de Valladolid, Valladolid, Spain.<br /><searchLink fieldCode="AU" term="%22Sanchez-Martinez+J%22">Sanchez-Martinez J</searchLink>; National Influenza Centre, Valladolid, Spain.; Fundación Instituto de Estudios de Ciencias de la Salud de Castilla y León, Soria, Spain.<br /><searchLink fieldCode="AU" term="%22Rodriguez-Crespo+C%22">Rodriguez-Crespo C</searchLink>; National Influenza Centre, Valladolid, Spain.; Fundación Instituto de Estudios de Ciencias de la Salud de Castilla y León, Soria, Spain.<br /><searchLink fieldCode="AU" term="%22Galindo-Carretero+S%22">Galindo-Carretero S</searchLink>; National Influenza Centre, Valladolid, Spain.; Fundación Instituto de Estudios de Ciencias de la Salud de Castilla y León, Soria, Spain.<br /><searchLink fieldCode="AU" term="%22Iglesia-Aparicio+R%22">Iglesia-Aparicio R</searchLink>; National Influenza Centre, Valladolid, Spain.; Fundación Instituto de Estudios de Ciencias de la Salud de Castilla y León, Soria, Spain.<br /><searchLink fieldCode="AU" term="%22Lopez-Gonzalo+C%22">Lopez-Gonzalo C</searchLink>; National Influenza Centre, Valladolid, Spain.; Fundación Instituto de Estudios de Ciencias de la Salud de Castilla y León, Soria, Spain.<br /><searchLink fieldCode="AU" term="%22Antón-Contreras+A%22">Antón-Contreras A</searchLink>; National Influenza Centre, Valladolid, Spain.; Fundación Instituto de Estudios de Ciencias de la Salud de Castilla y León, Soria, Spain.<br /><searchLink fieldCode="AU" term="%22Rojo-Rello+S%22">Rojo-Rello S</searchLink>; National Influenza Centre, Valladolid, Spain.; Microbiology Area, Faculty of Medicine, University of Valladolid, Spain.; Hospital Clínico Universitario de Valladolid, Valladolid, Spain.<br /><searchLink fieldCode="AU" term="%22Dominguez-Gil+M%22">Dominguez-Gil M</searchLink>; National Influenza Centre, Valladolid, Spain.; Microbiology Area, Faculty of Medicine, University of Valladolid, Spain.; Hospital Universitario Rio Hortega, Valladolid, Spain.<br /><searchLink fieldCode="AU" term="%22Hernández+M%22">Hernández M</searchLink>; National Influenza Centre, Valladolid, Spain.; Microbiology Area, Faculty of Medicine, University of Valladolid, Spain.<br /><searchLink fieldCode="AU" term="%22Eiros+JM%22">Eiros JM</searchLink>; National Influenza Centre, Valladolid, Spain.; Microbiology Area, Faculty of Medicine, University of Valladolid, Spain.; Hospital Clínico Universitario de Valladolid, Valladolid, Spain.; Hospital Universitario Rio Hortega, Valladolid, Spain.; Centro de Investigaciones Biomedicas en Red en Enfermedades Infecciosas (CIBERINFEC), Madrid, Spain.<br /><searchLink fieldCode="AU" term="%22Nistal-Villan+E%22">Nistal-Villan E</searchLink>; Microbiology Section, Departamento de Ciencias, Farmacéuticas y de la Salud, Facultad de Farmacia, Universidad San Pablo-CEU, CEU Universities, Madrid, Spain.; Institute of Applied Molecular Medicine Nemesio Diez (IMMA-ND), Department of Basic Medical Sciences, Facultad de Medicina, Universidad San Pablo-CEU, CEU Universities, Boadilla del Monte, Spain.<br /><searchLink fieldCode="AU" term="%22Sanz-Muñoz+I%22">Sanz-Muñoz I</searchLink>; National Influenza Centre, Valladolid, Spain.; Fundación Instituto de Estudios de Ciencias de la Salud de Castilla y León, Soria, Spain.; Centro de Investigaciones Biomedicas en Red en Enfermedades Infecciosas (CIBERINFEC), Madrid, Spain.
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