SIRT3/AARS2 regulates SOD2 lactylation to determine neuronal fate in TBI.

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Title: SIRT3/AARS2 regulates SOD2 lactylation to determine neuronal fate in TBI.
Authors: Song J; Department of Emergency Medicine, The General Hospital of Western Theater Command (Affiliated Hospital of Southwest Jiaotong University), College of Medicine, Southwest Jiaotong University, Chengdu, 610031, Sichuan, China.; Department of Critical Care Medicine, Chengdu Fifth People's Hospital (The Second Clinical Medical College, Affiliated Fifth People's Hospital of Chengdu University of Traditional Chinese Medicine), Chengdu, 611130, China., Liu J; Department of Anesthesiology, Chengdu Fifth People's Hospital, (The Second Clinical Medical College, Affiliated Fifth People's Hospital of Chengdu University of Traditional Chinese Medicine), Chengdu, 611130, China., Fan W; Department of Hyperbaric Oxygen Medicine, The General Hospital of Western Theater Command (Affiliated Hospital of Southwest Jiaotong University), College of Medicine, Southwest Jiaotong University, Chengdu, 610031, Sichuan, China., Gou F; Department of Emergency Medicine, The General Hospital of Western Theater Command (Affiliated Hospital of Southwest Jiaotong University), College of Medicine, Southwest Jiaotong University, Chengdu, 610031, Sichuan, China., Yang H; Department of Emergency Medicine, The General Hospital of Western Theater Command (Affiliated Hospital of Southwest Jiaotong University), College of Medicine, Southwest Jiaotong University, Chengdu, 610031, Sichuan, China., Wang P; Department of Critical Care Medicine, Chengdu Fifth People's Hospital (The Second Clinical Medical College, Affiliated Fifth People's Hospital of Chengdu University of Traditional Chinese Medicine), Chengdu, 611130, China. 2710924996@qq.com., Yang X; Department of Emergency Medicine, The General Hospital of Western Theater Command (Affiliated Hospital of Southwest Jiaotong University), College of Medicine, Southwest Jiaotong University, Chengdu, 610031, Sichuan, China. bacelona1978@163.com., Tao K; Department of Emergency Medicine, The General Hospital of Western Theater Command (Affiliated Hospital of Southwest Jiaotong University), College of Medicine, Southwest Jiaotong University, Chengdu, 610031, Sichuan, China. taokai08@163.com.; Department of Experimental Surgery, The Second Affiliated Hospital of Air Force Medical University, Xi'an, 710000, Shaanxi Province, China. taokai08@163.com.
Source: Molecular neurobiology [Mol Neurobiol] 2026 Jun 26; Vol. 63 (1). Date of Electronic Publication: 2026 Jun 26.
Publication Type: Journal Article
Journal Info: Publisher: Humana Press Country of Publication: United States NLM ID: 8900963 Publication Model: Electronic Cited Medium: Internet ISSN: 1559-1182 (Electronic) Linking ISSN: 08937648 NLM ISO Abbreviation: Mol Neurobiol Subsets: MEDLINE
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  Data: SIRT3/AARS2 regulates SOD2 lactylation to determine neuronal fate in TBI.
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  Data: <searchLink fieldCode="AU" term="%22Song+J%22">Song J</searchLink>; Department of Emergency Medicine, The General Hospital of Western Theater Command (Affiliated Hospital of Southwest Jiaotong University), College of Medicine, Southwest Jiaotong University, Chengdu, 610031, Sichuan, China.; Department of Critical Care Medicine, Chengdu Fifth People's Hospital (The Second Clinical Medical College, Affiliated Fifth People's Hospital of Chengdu University of Traditional Chinese Medicine), Chengdu, 611130, China.<br /><searchLink fieldCode="AU" term="%22Liu+J%22">Liu J</searchLink>; Department of Anesthesiology, Chengdu Fifth People's Hospital, (The Second Clinical Medical College, Affiliated Fifth People's Hospital of Chengdu University of Traditional Chinese Medicine), Chengdu, 611130, China.<br /><searchLink fieldCode="AU" term="%22Fan+W%22">Fan W</searchLink>; Department of Hyperbaric Oxygen Medicine, The General Hospital of Western Theater Command (Affiliated Hospital of Southwest Jiaotong University), College of Medicine, Southwest Jiaotong University, Chengdu, 610031, Sichuan, China.<br /><searchLink fieldCode="AU" term="%22Gou+F%22">Gou F</searchLink>; Department of Emergency Medicine, The General Hospital of Western Theater Command (Affiliated Hospital of Southwest Jiaotong University), College of Medicine, Southwest Jiaotong University, Chengdu, 610031, Sichuan, China.<br /><searchLink fieldCode="AU" term="%22Yang+H%22">Yang H</searchLink>; Department of Emergency Medicine, The General Hospital of Western Theater Command (Affiliated Hospital of Southwest Jiaotong University), College of Medicine, Southwest Jiaotong University, Chengdu, 610031, Sichuan, China.<br /><searchLink fieldCode="AU" term="%22Wang+P%22">Wang P</searchLink>; Department of Critical Care Medicine, Chengdu Fifth People's Hospital (The Second Clinical Medical College, Affiliated Fifth People's Hospital of Chengdu University of Traditional Chinese Medicine), Chengdu, 611130, China. 2710924996@qq.com.<br /><searchLink fieldCode="AU" term="%22Yang+X%22">Yang X</searchLink>; Department of Emergency Medicine, The General Hospital of Western Theater Command (Affiliated Hospital of Southwest Jiaotong University), College of Medicine, Southwest Jiaotong University, Chengdu, 610031, Sichuan, China. bacelona1978@163.com.<br /><searchLink fieldCode="AU" term="%22Tao+K%22">Tao K</searchLink>; Department of Emergency Medicine, The General Hospital of Western Theater Command (Affiliated Hospital of Southwest Jiaotong University), College of Medicine, Southwest Jiaotong University, Chengdu, 610031, Sichuan, China. taokai08@163.com.; Department of Experimental Surgery, The Second Affiliated Hospital of Air Force Medical University, Xi'an, 710000, Shaanxi Province, China. taokai08@163.com.
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  Data: <searchLink fieldCode="JN" term="%228900963%22">Molecular neurobiology</searchLink> [Mol Neurobiol] 2026 Jun 26; Vol. 63 (1). <i>Date of Electronic Publication: </i>2026 Jun 26.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Humana+Press%22">Humana Press </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>8900963 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1559-1182 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2208937648%22">08937648 </searchLink><i>NLM ISO Abbreviation: </i>Mol Neurobiol <i>Subsets: </i>MEDLINE
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        Value: 10.1007/s12035-026-05931-8
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              Text: 2026 Jun 26
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              Y: 2026
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