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CircZBTB46, a promising therapeutic target in crizotinib resistant ALK-positive T lymphomas.

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Title: CircZBTB46, a promising therapeutic target in crizotinib resistant ALK-positive T lymphomas.
Authors: Babin L; Univ Toulouse, CNRS, INSERM, CRCT (Cancer Research Center of Toulouse), UMR-1037, UMR-5071, Institut Universitaire du Cancer, Toulouse, France.; Laboratoire d'Excellence Toulouse Cancer-TOUCAN, Toulouse, France., Andraos E; Univ Toulouse, CNRS, INSERM, CRCT (Cancer Research Center of Toulouse), UMR-1037, UMR-5071, Institut Universitaire du Cancer, Toulouse, France.; Laboratoire d'Excellence Toulouse Cancer-TOUCAN, Toulouse, France., Fuchs S; Univ Toulouse, CNRS, INSERM, CRCT (Cancer Research Center of Toulouse), UMR-1037, UMR-5071, Institut Universitaire du Cancer, Toulouse, France.; Laboratoire d'Excellence Toulouse Cancer-TOUCAN, Toulouse, France.; Department of Pediatric Oncology and Hematology, Charité - Universitätsmedizin, Corporate Member of Freie Universität Berlin and Humboldt-Universität, Berlin, Germany.; German Cancer Consortium (DKTK), Partner Site Berlin, a Partnership Between DKFZ and Charité-Universitätsmedizin, Berlin Institute of Health at Charité - Universitätsmedizin Berlin, Berlin, Germany., Bessière C; Univ Toulouse, CNRS, INSERM, CRCT (Cancer Research Center of Toulouse), UMR-1037, UMR-5071, Institut Universitaire du Cancer, Toulouse, France.; Laboratoire d'Excellence Toulouse Cancer-TOUCAN, Toulouse, France., Colras L; Univ Toulouse, CNRS, INSERM, CRCT (Cancer Research Center of Toulouse), UMR-1037, UMR-5071, Institut Universitaire du Cancer, Toulouse, France.; Laboratoire d'Excellence Toulouse Cancer-TOUCAN, Toulouse, France., Dailhau S; Univ Toulouse, CNRS, INSERM, CRCT (Cancer Research Center of Toulouse), UMR-1037, UMR-5071, Institut Universitaire du Cancer, Toulouse, France.; Laboratoire d'Excellence Toulouse Cancer-TOUCAN, Toulouse, France., Quelen C; Univ Toulouse, CNRS, INSERM, CRCT (Cancer Research Center of Toulouse), UMR-1037, UMR-5071, Institut Universitaire du Cancer, Toulouse, France., Pinto C; Univ Toulouse, CNRS, INSERM, CRCT (Cancer Research Center of Toulouse), UMR-1037, UMR-5071, Institut Universitaire du Cancer, Toulouse, France., Daoudi I; Univ Toulouse, CNRS, INSERM, CRCT (Cancer Research Center of Toulouse), UMR-1037, UMR-5071, Institut Universitaire du Cancer, Toulouse, France., Pfeifer R; Univ Toulouse, CNRS, INSERM, CRCT (Cancer Research Center of Toulouse), UMR-1037, UMR-5071, Institut Universitaire du Cancer, Toulouse, France., Zamani A; Univ Toulouse, CNRS, INSERM, CRCT (Cancer Research Center of Toulouse), UMR-1037, UMR-5071, Institut Universitaire du Cancer, Toulouse, France., Bousquet M; Univ Toulouse, CNRS, INSERM, CRCT (Cancer Research Center of Toulouse), UMR-1037, UMR-5071, Institut Universitaire du Cancer, Toulouse, France., Pyronnet S; Univ Toulouse, CNRS, INSERM, CRCT (Cancer Research Center of Toulouse), UMR-1037, UMR-5071, Institut Universitaire du Cancer, Toulouse, France.; Laboratoire d'Excellence Toulouse Cancer-TOUCAN, Toulouse, France., Gaspin C; INRAE, BioinfOmics, GenoToul Bioinformatics Facility, Université de Toulouse, Castanet-Tolosan, Toulouse, France.; INRAE, MIAT, Université de Toulouse, Castanet-Tolosan, Toulouse, France., Lamant L; Univ Toulouse, CNRS, INSERM, CRCT (Cancer Research Center of Toulouse), UMR-1037, UMR-5071, Institut Universitaire du Cancer, Toulouse, France.; Laboratoire d'Excellence Toulouse Cancer-TOUCAN, Toulouse, France., Meggetto F; Univ Toulouse, CNRS, INSERM, CRCT (Cancer Research Center of Toulouse), UMR-1037, UMR-5071, Institut Universitaire du Cancer, Toulouse, France. fabienne.meggetto@inserm.fr.; Laboratoire d'Excellence Toulouse Cancer-TOUCAN, Toulouse, France. fabienne.meggetto@inserm.fr.
Source: Leukemia [Leukemia] 2026 Aug; Vol. 40 (8), pp. 1735-1747. Date of Electronic Publication: 2026 Jun 26.
Publication Type: Journal Article
Journal Info: Publisher: Nature Publishing Group, Specialist Journals Country of Publication: England NLM ID: 8704895 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-5551 (Electronic) Linking ISSN: 08876924 NLM ISO Abbreviation: Leukemia Subsets: MEDLINE
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  Data: CircZBTB46, a promising therapeutic target in crizotinib resistant ALK-positive T lymphomas.
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  Data: <searchLink fieldCode="AU" term="%22Babin+L%22">Babin L</searchLink>; Univ Toulouse, CNRS, INSERM, CRCT (Cancer Research Center of Toulouse), UMR-1037, UMR-5071, Institut Universitaire du Cancer, Toulouse, France.; Laboratoire d'Excellence Toulouse Cancer-TOUCAN, Toulouse, France.<br /><searchLink fieldCode="AU" term="%22Andraos+E%22">Andraos E</searchLink>; Univ Toulouse, CNRS, INSERM, CRCT (Cancer Research Center of Toulouse), UMR-1037, UMR-5071, Institut Universitaire du Cancer, Toulouse, France.; Laboratoire d'Excellence Toulouse Cancer-TOUCAN, Toulouse, France.<br /><searchLink fieldCode="AU" term="%22Fuchs+S%22">Fuchs S</searchLink>; Univ Toulouse, CNRS, INSERM, CRCT (Cancer Research Center of Toulouse), UMR-1037, UMR-5071, Institut Universitaire du Cancer, Toulouse, France.; Laboratoire d'Excellence Toulouse Cancer-TOUCAN, Toulouse, France.; Department of Pediatric Oncology and Hematology, Charité - Universitätsmedizin, Corporate Member of Freie Universität Berlin and Humboldt-Universität, Berlin, Germany.; German Cancer Consortium (DKTK), Partner Site Berlin, a Partnership Between DKFZ and Charité-Universitätsmedizin, Berlin Institute of Health at Charité - Universitätsmedizin Berlin, Berlin, Germany.<br /><searchLink fieldCode="AU" term="%22Bessière+C%22">Bessière C</searchLink>; Univ Toulouse, CNRS, INSERM, CRCT (Cancer Research Center of Toulouse), UMR-1037, UMR-5071, Institut Universitaire du Cancer, Toulouse, France.; Laboratoire d'Excellence Toulouse Cancer-TOUCAN, Toulouse, France.<br /><searchLink fieldCode="AU" term="%22Colras+L%22">Colras L</searchLink>; Univ Toulouse, CNRS, INSERM, CRCT (Cancer Research Center of Toulouse), UMR-1037, UMR-5071, Institut Universitaire du Cancer, Toulouse, France.; Laboratoire d'Excellence Toulouse Cancer-TOUCAN, Toulouse, France.<br /><searchLink fieldCode="AU" term="%22Dailhau+S%22">Dailhau S</searchLink>; Univ Toulouse, CNRS, INSERM, CRCT (Cancer Research Center of Toulouse), UMR-1037, UMR-5071, Institut Universitaire du Cancer, Toulouse, France.; Laboratoire d'Excellence Toulouse Cancer-TOUCAN, Toulouse, France.<br /><searchLink fieldCode="AU" term="%22Quelen+C%22">Quelen C</searchLink>; Univ Toulouse, CNRS, INSERM, CRCT (Cancer Research Center of Toulouse), UMR-1037, UMR-5071, Institut Universitaire du Cancer, Toulouse, France.<br /><searchLink fieldCode="AU" term="%22Pinto+C%22">Pinto C</searchLink>; Univ Toulouse, CNRS, INSERM, CRCT (Cancer Research Center of Toulouse), UMR-1037, UMR-5071, Institut Universitaire du Cancer, Toulouse, France.<br /><searchLink fieldCode="AU" term="%22Daoudi+I%22">Daoudi I</searchLink>; Univ Toulouse, CNRS, INSERM, CRCT (Cancer Research Center of Toulouse), UMR-1037, UMR-5071, Institut Universitaire du Cancer, Toulouse, France.<br /><searchLink fieldCode="AU" term="%22Pfeifer+R%22">Pfeifer R</searchLink>; Univ Toulouse, CNRS, INSERM, CRCT (Cancer Research Center of Toulouse), UMR-1037, UMR-5071, Institut Universitaire du Cancer, Toulouse, France.<br /><searchLink fieldCode="AU" term="%22Zamani+A%22">Zamani A</searchLink>; Univ Toulouse, CNRS, INSERM, CRCT (Cancer Research Center of Toulouse), UMR-1037, UMR-5071, Institut Universitaire du Cancer, Toulouse, France.<br /><searchLink fieldCode="AU" term="%22Bousquet+M%22">Bousquet M</searchLink>; Univ Toulouse, CNRS, INSERM, CRCT (Cancer Research Center of Toulouse), UMR-1037, UMR-5071, Institut Universitaire du Cancer, Toulouse, France.<br /><searchLink fieldCode="AU" term="%22Pyronnet+S%22">Pyronnet S</searchLink>; Univ Toulouse, CNRS, INSERM, CRCT (Cancer Research Center of Toulouse), UMR-1037, UMR-5071, Institut Universitaire du Cancer, Toulouse, France.; Laboratoire d'Excellence Toulouse Cancer-TOUCAN, Toulouse, France.<br /><searchLink fieldCode="AU" term="%22Gaspin+C%22">Gaspin C</searchLink>; INRAE, BioinfOmics, GenoToul Bioinformatics Facility, Université de Toulouse, Castanet-Tolosan, Toulouse, France.; INRAE, MIAT, Université de Toulouse, Castanet-Tolosan, Toulouse, France.<br /><searchLink fieldCode="AU" term="%22Lamant+L%22">Lamant L</searchLink>; Univ Toulouse, CNRS, INSERM, CRCT (Cancer Research Center of Toulouse), UMR-1037, UMR-5071, Institut Universitaire du Cancer, Toulouse, France.; Laboratoire d'Excellence Toulouse Cancer-TOUCAN, Toulouse, France.<br /><searchLink fieldCode="AU" term="%22Meggetto+F%22">Meggetto F</searchLink>; Univ Toulouse, CNRS, INSERM, CRCT (Cancer Research Center of Toulouse), UMR-1037, UMR-5071, Institut Universitaire du Cancer, Toulouse, France. fabienne.meggetto@inserm.fr.; Laboratoire d'Excellence Toulouse Cancer-TOUCAN, Toulouse, France. fabienne.meggetto@inserm.fr.
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