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Antigen-scaffolds loaded with hyper-stable neoleukin-2/15 expand antigen-specific T cells with a favorable phenotype for adoptive cell therapy.

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Title: Antigen-scaffolds loaded with hyper-stable neoleukin-2/15 expand antigen-specific T cells with a favorable phenotype for adoptive cell therapy.
Authors: Ormhøj M; Experimental and Translational Immunology, Department for Health Technology, Technical University of Denmark, Kongens Lyngby, Denmark.; Biotechnology, Department of Green Technology, University of Southern Denmark, Odense, Denmark., Munk KK; Experimental and Translational Immunology, Department for Health Technology, Technical University of Denmark, Kongens Lyngby, Denmark., Tvingsholm S; Experimental and Translational Immunology, Department for Health Technology, Technical University of Denmark, Kongens Lyngby, Denmark., Ramanathan K; Experimental and Translational Immunology, Department for Health Technology, Technical University of Denmark, Kongens Lyngby, Denmark., Bentzen AK; Experimental and Translational Immunology, Department for Health Technology, Technical University of Denmark, Kongens Lyngby, Denmark., Kladis G; Experimental and Translational Immunology, Department for Health Technology, Technical University of Denmark, Kongens Lyngby, Denmark., Aasbjerg GN; Experimental and Translational Immunology, Department for Health Technology, Technical University of Denmark, Kongens Lyngby, Denmark., Nos G; Experimental and Translational Immunology, Department for Health Technology, Technical University of Denmark, Kongens Lyngby, Denmark., Tamhane T; Experimental and Translational Immunology, Department for Health Technology, Technical University of Denmark, Kongens Lyngby, Denmark., Halldórsdóttir HR; Experimental and Translational Immunology, Department for Health Technology, Technical University of Denmark, Kongens Lyngby, Denmark., Jakobsen SN; Experimental and Translational Immunology, Department for Health Technology, Technical University of Denmark, Kongens Lyngby, Denmark., Frej MS; Experimental and Translational Immunology, Department for Health Technology, Technical University of Denmark, Kongens Lyngby, Denmark., Johansen KH; Experimental and Translational Immunology, Department for Health Technology, Technical University of Denmark, Kongens Lyngby, Denmark., Kadivar M; Experimental and Translational Immunology, Department for Health Technology, Technical University of Denmark, Kongens Lyngby, Denmark., Hadrup SR; Experimental and Translational Immunology, Department for Health Technology, Technical University of Denmark, Kongens Lyngby, Denmark.
Source: Frontiers in immunology [Front Immunol] 2026 Jun 11; Vol. 17, pp. 1804678. Date of Electronic Publication: 2026 Jun 11 (Print Publication: 2026).
Publication Type: Journal Article
Journal Info: Publisher: Frontiers Research Foundation] Country of Publication: Switzerland NLM ID: 101560960 Publication Model: eCollection Cited Medium: Internet ISSN: 1664-3224 (Electronic) Linking ISSN: 16643224 NLM ISO Abbreviation: Front Immunol Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Antigen-scaffolds loaded with hyper-stable neoleukin-2/15 expand antigen-specific T cells with a favorable phenotype for adoptive cell therapy.
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  Data: <searchLink fieldCode="AU" term="%22Ormhøj+M%22">Ormhøj M</searchLink>; Experimental and Translational Immunology, Department for Health Technology, Technical University of Denmark, Kongens Lyngby, Denmark.; Biotechnology, Department of Green Technology, University of Southern Denmark, Odense, Denmark.<br /><searchLink fieldCode="AU" term="%22Munk+KK%22">Munk KK</searchLink>; Experimental and Translational Immunology, Department for Health Technology, Technical University of Denmark, Kongens Lyngby, Denmark.<br /><searchLink fieldCode="AU" term="%22Tvingsholm+S%22">Tvingsholm S</searchLink>; Experimental and Translational Immunology, Department for Health Technology, Technical University of Denmark, Kongens Lyngby, Denmark.<br /><searchLink fieldCode="AU" term="%22Ramanathan+K%22">Ramanathan K</searchLink>; Experimental and Translational Immunology, Department for Health Technology, Technical University of Denmark, Kongens Lyngby, Denmark.<br /><searchLink fieldCode="AU" term="%22Bentzen+AK%22">Bentzen AK</searchLink>; Experimental and Translational Immunology, Department for Health Technology, Technical University of Denmark, Kongens Lyngby, Denmark.<br /><searchLink fieldCode="AU" term="%22Kladis+G%22">Kladis G</searchLink>; Experimental and Translational Immunology, Department for Health Technology, Technical University of Denmark, Kongens Lyngby, Denmark.<br /><searchLink fieldCode="AU" term="%22Aasbjerg+GN%22">Aasbjerg GN</searchLink>; Experimental and Translational Immunology, Department for Health Technology, Technical University of Denmark, Kongens Lyngby, Denmark.<br /><searchLink fieldCode="AU" term="%22Nos+G%22">Nos G</searchLink>; Experimental and Translational Immunology, Department for Health Technology, Technical University of Denmark, Kongens Lyngby, Denmark.<br /><searchLink fieldCode="AU" term="%22Tamhane+T%22">Tamhane T</searchLink>; Experimental and Translational Immunology, Department for Health Technology, Technical University of Denmark, Kongens Lyngby, Denmark.<br /><searchLink fieldCode="AU" term="%22Halldórsdóttir+HR%22">Halldórsdóttir HR</searchLink>; Experimental and Translational Immunology, Department for Health Technology, Technical University of Denmark, Kongens Lyngby, Denmark.<br /><searchLink fieldCode="AU" term="%22Jakobsen+SN%22">Jakobsen SN</searchLink>; Experimental and Translational Immunology, Department for Health Technology, Technical University of Denmark, Kongens Lyngby, Denmark.<br /><searchLink fieldCode="AU" term="%22Frej+MS%22">Frej MS</searchLink>; Experimental and Translational Immunology, Department for Health Technology, Technical University of Denmark, Kongens Lyngby, Denmark.<br /><searchLink fieldCode="AU" term="%22Johansen+KH%22">Johansen KH</searchLink>; Experimental and Translational Immunology, Department for Health Technology, Technical University of Denmark, Kongens Lyngby, Denmark.<br /><searchLink fieldCode="AU" term="%22Kadivar+M%22">Kadivar M</searchLink>; Experimental and Translational Immunology, Department for Health Technology, Technical University of Denmark, Kongens Lyngby, Denmark.<br /><searchLink fieldCode="AU" term="%22Hadrup+SR%22">Hadrup SR</searchLink>; Experimental and Translational Immunology, Department for Health Technology, Technical University of Denmark, Kongens Lyngby, Denmark.
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