Dibutyl phthalate induces sarcopenia via TNFα/TNFR1-mediated proteolytic and pyroptotic axes: evidence from NHANES and experimental models.

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Title: Dibutyl phthalate induces sarcopenia via TNFα/TNFR1-mediated proteolytic and pyroptotic axes: evidence from NHANES and experimental models.
Authors: Yi X; School of Pharmaceutical Sciences, Zhejiang Chinese Medical University, Hangzhou, Zhejiang, China.; Center for Biobased Materials, Muyuan Laboratory, Zhengzhou, Henan, China.; The First Affiliated Hospital of Zhejiang Chinese Medical University (Zhejiang Provincial Hospital of Traditional Chinese Medicine), Hangzhou, Zhejiang, China.; School of Life Sciences, Westlake University, Hangzhou, Zhejiang, China., Li J; The First Affiliated Hospital of Zhejiang Chinese Medical University (Zhejiang Provincial Hospital of Traditional Chinese Medicine), Hangzhou, Zhejiang, China., Long X; The First Affiliated Hospital of Zhejiang Chinese Medical University (Zhejiang Provincial Hospital of Traditional Chinese Medicine), Hangzhou, Zhejiang, China., Hu X; The First Affiliated Hospital of Zhejiang Chinese Medical University (Zhejiang Provincial Hospital of Traditional Chinese Medicine), Hangzhou, Zhejiang, China., Yi L; Department of Encephalopathy (Department of Neurology), Yunnan Provincial Hospital of Traditional Chinese Medicine, Kunming, Yunnan, China., Liu L; School of Pharmaceutical Sciences, Zhejiang Chinese Medical University, Hangzhou, Zhejiang, China., Lu X; The First Affiliated Hospital of Zhejiang Chinese Medical University (Zhejiang Provincial Hospital of Traditional Chinese Medicine), Hangzhou, Zhejiang, China., Xu T; The First Affiliated Hospital of Zhejiang Chinese Medical University (Zhejiang Provincial Hospital of Traditional Chinese Medicine), Hangzhou, Zhejiang, China., Chen Y; School of Stomatology, Zhejiang Chinese Medical University, Hangzhou, Zhejiang, China., Zheng HF; School of Life Sciences, Westlake University, Hangzhou, Zhejiang, China.; Suzhou Laboratory of Precision Health and Data Science, The Second Affiliated Hospital of Soochow University, Suzhou, Jiangsu, China.; Institute of Health Data Science, Soochow University, Suzhou, Jiangsu, China., Ruan H; The First Affiliated Hospital of Zhejiang Chinese Medical University (Zhejiang Provincial Hospital of Traditional Chinese Medicine), Hangzhou, Zhejiang, China., Tao J; Center for Biobased Materials, Muyuan Laboratory, Zhengzhou, Henan, China.; School of Life Sciences, Westlake University, Hangzhou, Zhejiang, China.
Source: Frontiers in immunology [Front Immunol] 2026 Jun 12; Vol. 17, pp. 1853039. Date of Electronic Publication: 2026 Jun 12 (Print Publication: 2026).
Publication Type: Journal Article
Journal Info: Publisher: Frontiers Research Foundation] Country of Publication: Switzerland NLM ID: 101560960 Publication Model: eCollection Cited Medium: Internet ISSN: 1664-3224 (Electronic) Linking ISSN: 16643224 NLM ISO Abbreviation: Front Immunol Subsets: MEDLINE
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  Data: Dibutyl phthalate induces sarcopenia via TNFα/TNFR1-mediated proteolytic and pyroptotic axes: evidence from NHANES and experimental models.
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  Data: <searchLink fieldCode="AU" term="%22Yi+X%22">Yi X</searchLink>; School of Pharmaceutical Sciences, Zhejiang Chinese Medical University, Hangzhou, Zhejiang, China.; Center for Biobased Materials, Muyuan Laboratory, Zhengzhou, Henan, China.; The First Affiliated Hospital of Zhejiang Chinese Medical University (Zhejiang Provincial Hospital of Traditional Chinese Medicine), Hangzhou, Zhejiang, China.; School of Life Sciences, Westlake University, Hangzhou, Zhejiang, China.<br /><searchLink fieldCode="AU" term="%22Li+J%22">Li J</searchLink>; The First Affiliated Hospital of Zhejiang Chinese Medical University (Zhejiang Provincial Hospital of Traditional Chinese Medicine), Hangzhou, Zhejiang, China.<br /><searchLink fieldCode="AU" term="%22Long+X%22">Long X</searchLink>; The First Affiliated Hospital of Zhejiang Chinese Medical University (Zhejiang Provincial Hospital of Traditional Chinese Medicine), Hangzhou, Zhejiang, China.<br /><searchLink fieldCode="AU" term="%22Hu+X%22">Hu X</searchLink>; The First Affiliated Hospital of Zhejiang Chinese Medical University (Zhejiang Provincial Hospital of Traditional Chinese Medicine), Hangzhou, Zhejiang, China.<br /><searchLink fieldCode="AU" term="%22Yi+L%22">Yi L</searchLink>; Department of Encephalopathy (Department of Neurology), Yunnan Provincial Hospital of Traditional Chinese Medicine, Kunming, Yunnan, China.<br /><searchLink fieldCode="AU" term="%22Liu+L%22">Liu L</searchLink>; School of Pharmaceutical Sciences, Zhejiang Chinese Medical University, Hangzhou, Zhejiang, China.<br /><searchLink fieldCode="AU" term="%22Lu+X%22">Lu X</searchLink>; The First Affiliated Hospital of Zhejiang Chinese Medical University (Zhejiang Provincial Hospital of Traditional Chinese Medicine), Hangzhou, Zhejiang, China.<br /><searchLink fieldCode="AU" term="%22Xu+T%22">Xu T</searchLink>; The First Affiliated Hospital of Zhejiang Chinese Medical University (Zhejiang Provincial Hospital of Traditional Chinese Medicine), Hangzhou, Zhejiang, China.<br /><searchLink fieldCode="AU" term="%22Chen+Y%22">Chen Y</searchLink>; School of Stomatology, Zhejiang Chinese Medical University, Hangzhou, Zhejiang, China.<br /><searchLink fieldCode="AU" term="%22Zheng+HF%22">Zheng HF</searchLink>; School of Life Sciences, Westlake University, Hangzhou, Zhejiang, China.; Suzhou Laboratory of Precision Health and Data Science, The Second Affiliated Hospital of Soochow University, Suzhou, Jiangsu, China.; Institute of Health Data Science, Soochow University, Suzhou, Jiangsu, China.<br /><searchLink fieldCode="AU" term="%22Ruan+H%22">Ruan H</searchLink>; The First Affiliated Hospital of Zhejiang Chinese Medical University (Zhejiang Provincial Hospital of Traditional Chinese Medicine), Hangzhou, Zhejiang, China.<br /><searchLink fieldCode="AU" term="%22Tao+J%22">Tao J</searchLink>; Center for Biobased Materials, Muyuan Laboratory, Zhengzhou, Henan, China.; School of Life Sciences, Westlake University, Hangzhou, Zhejiang, China.
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  Data: <searchLink fieldCode="JN" term="%22101560960%22">Frontiers in immunology</searchLink> [Front Immunol] 2026 Jun 12; Vol. 17, pp. 1853039. <i>Date of Electronic Publication: </i>2026 Jun 12 (<i>Print Publication: </i>2026).
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Frontiers+Research+Foundation]%22">Frontiers Research Foundation] </searchLink><i>Country of Publication: </i>Switzerland <i>NLM ID: </i>101560960 <i>Publication Model: </i>eCollection <i>Cited Medium: </i>Internet <i>ISSN: </i>1664-3224 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2216643224%22">16643224 </searchLink><i>NLM ISO Abbreviation: </i>Front Immunol <i>Subsets: </i>MEDLINE
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              Text: 2026 Jun 12
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