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Microbiome-Targeted Antibiotics Provide No Additional Microbiologic or Inflammatory Benefit during Cystic Fibrosis Pulmonary Exacerbations: Results from the CFMATTERS Trial.

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Bibliographic Details
Title: Microbiome-Targeted Antibiotics Provide No Additional Microbiologic or Inflammatory Benefit during Cystic Fibrosis Pulmonary Exacerbations: Results from the CFMATTERS Trial.
Authors: Einarsson GG; School of Pharmacy, Queen's University Belfast, Belfast, United Kingdom., Lee AJ; School of Pharmacy, Queen's University Belfast, Belfast, United Kingdom., Alfahl Z; School of Pharmacy, Queen's University Belfast, Belfast, United Kingdom., Kerrigan L; Airway Innate Immunity Research (AiiR) Group, Wellcome-Wolfson Institute for Experimental Medicine, Queen's University Belfast, Belfast, United Kingdom., Eustace JA; Cork Centre for Cystic Fibrosis (3CF), Cork University Hospital, University College Cork, Wilton, Cork, Ireland.; The HRB funded Clinical Research Facility, University College Cork, Cork, Ireland., Weldon S; Airway Innate Immunity Research (AiiR) Group, Wellcome-Wolfson Institute for Experimental Medicine, Queen's University Belfast, Belfast, United Kingdom., Plant BJ; Cork Centre for Cystic Fibrosis (3CF), Cork University Hospital, University College Cork, Wilton, Cork, Ireland.; The HRB funded Clinical Research Facility, University College Cork, Cork, Ireland.; Department of Medicine, University College Cork, Cork, Ireland., Elborn JS; School of Medicine, Dentistry and Biomedical Sciences, Queen's University Belfast, Belfast, United Kingdom., Taggart CC; Airway Innate Immunity Research (AiiR) Group, Wellcome-Wolfson Institute for Experimental Medicine, Queen's University Belfast, Belfast, United Kingdom., Mall MA; Department of Pediatric Respiratory Medicine, Immunology and Critical Care Medicine, Charité - Universitätsmedizin Berlin, Berlin, Germany.; German Center for Lung Research (DZL), associated partner site Berlin, Berlin, Germany.; German Center for Child and Adolescent Health (DZKJ), partner site Berlin, Berlin, Germany.; Cluster of Excellence ImmunoPreCept, Charité - Universitätsmedizin Berlin, Berlin, Germany., Tunney MM; School of Pharmacy, Queen's University Belfast, Belfast, United Kingdom.
Source: American journal of respiratory and critical care medicine [Am J Respir Crit Care Med] 2026 Jun 29. Date of Electronic Publication: 2026 Jun 29.
Publication Type: Journal Article
Journal Info: Publisher: American Thoracic Society Country of Publication: England NLM ID: 9421642 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1535-4970 (Electronic) Linking ISSN: 1073449X NLM ISO Abbreviation: Am J Respir Crit Care Med Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1535-4970
DOI:10.1093/ajrccm/aamag336