Perioperative systemic therapy versus surgery alone for resectable colorectal peritoneal-only metastases (CAIRO6): a randomised, open-label, phase 3 trial.

Saved in:
Bibliographic Details
Title: Perioperative systemic therapy versus surgery alone for resectable colorectal peritoneal-only metastases (CAIRO6): a randomised, open-label, phase 3 trial.
Authors: Rovers KP; Department of Surgery, Catharina Cancer Institute, Eindhoven, Netherlands. Electronic address: koen.rovers@catharinaziekenhuis.nlor., Bakkers C; Department of Surgery, Catharina Cancer Institute, Eindhoven, Netherlands., van den Heuvel TBM; Department of Surgery, Catharina Cancer Institute, Eindhoven, Netherlands., van de Vlasakker VCJ; Department of Surgery, Catharina Cancer Institute, Eindhoven, Netherlands., Kerkhoff TME; Department of Surgery, Catharina Cancer Institute, Eindhoven, Netherlands., Nienhuijs SW; Department of Surgery, Catharina Cancer Institute, Eindhoven, Netherlands., Burger JWA; Department of Surgery, Catharina Cancer Institute, Eindhoven, Netherlands., Creemers GM; Department of Medical Oncology, Catharina Cancer Institute, Eindhoven, Netherlands., van Hellemond IEG; Department of Medical Oncology, Catharina Cancer Institute, Eindhoven, Netherlands., Tuynman JB; Department of Surgery, Amsterdam UMC, Amsterdam, Netherlands., Kusters M; Department of Surgery, Amsterdam UMC, Amsterdam, Netherlands., Buffart TE; Department of Medical Oncology, Amsterdam UMC, Amsterdam, Netherlands., Aalbers AGJ; Department of Surgery, Netherlands Cancer Institute, Amsterdam, Netherlands., Kok NFM; Department of Surgery, Netherlands Cancer Institute, Amsterdam, Netherlands., Chalabi M; Department of Gastrointestinal Oncology, Netherlands Cancer Institute, Amsterdam, Netherlands., Boerma D; Department of Surgery, Sint Antonius Hospital, Nieuwegein, Netherlands., Brandt-Kerkhof ARM; Department of Surgery, Erasmus University Medical Centre, Rotterdam, Netherlands., de Reuver PR; Department of Surgery, Radboud University Medical Centre, Nijmegen, Netherlands., Hemmer PHJ; Department of Surgery, University Medical Centre Groningen, Groningen, Netherlands., van Grevenstein WMU; Department of Surgery, University Medical Centre Utrecht, Utrecht, Netherlands., van der Speeten K; Department of Surgery, Hospital Oost-Limburg, Genk, Belgium; Department of Life Sciences, BIOMED Research Institute, University Hasselt, Diepenbeek, Belgium., Snaebjornsson P; Department of Pathology, Netherlands Cancer Institute, Amsterdam, Netherlands; Faculty of Medicine, University of Iceland, Reykjavik, Iceland., Lee-Law PY; Department of Pathology, Catharina Cancer Institute, Eindhoven, Netherlands., Lahaye MJ; Department of Radiology, Netherlands Cancer Institute, Amsterdam, Netherlands; GROW-Institute for Oncology and Reproduction, Maastricht University, Maastricht, Netherlands., Nederend J; Department of Radiology, Catharina Cancer Institute, Eindhoven, Netherlands., Kranenburg O; Utrecht Platform for Organoid Technology, University Medical Centre Utrecht, Utrecht, Netherlands., Bouma JM; Clinical Trials Office, Netherlands Comprehensive Cancer Organisation, Utrecht, Netherlands., Punt CJA; Department of Epidemiology, Julius Centre for Health Sciences and Primary Care, Utrecht, Netherlands., Dijkgraaf MGW; Department of Epidemiology and Data Science, Amsterdam UMC, Amsterdam, Netherlands., Tanis PJ; Department of Surgery, Erasmus University Medical Centre, Rotterdam, Netherlands., de Hingh IHJT; Department of Surgery, Catharina Cancer Institute, Eindhoven, Netherlands; GROW-Institute for Oncology and Reproduction, Maastricht University, Maastricht, Netherlands; Department of Research and Development, Netherlands Comprehensive Cancer Organisation, Utrecht, Netherlands. Electronic address: ignace.d.hingh@catharinaziekenhuis.nl.
Corporate Authors: CAIRO6 Investigators, Dutch Peritoneal Oncology Group and the Dutch Colorectal Cancer Group
Source: The Lancet. Oncology [Lancet Oncol] 2026 Jul; Vol. 27 (7), pp. 849-863.
Publication Type: Journal Article; Clinical Trial, Phase III; Randomized Controlled Trial; Multicenter Study; Comparative Study
Journal Info: Publisher: Lancet Pub. Group Country of Publication: England NLM ID: 100957246 Publication Model: Print Cited Medium: Internet ISSN: 1474-5488 (Electronic) Linking ISSN: 14702045 NLM ISO Abbreviation: Lancet Oncol Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1474-5488
DOI:10.1016/S1470-2045(26)00085-9