NRF1 Activates the AMPK/SIRT1/PGC-1α/TFAM Axis to Suppress EMT and Tumor Progression in Lung Adenocarcinoma.

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Title: NRF1 Activates the AMPK/SIRT1/PGC-1α/TFAM Axis to Suppress EMT and Tumor Progression in Lung Adenocarcinoma.
Authors: Wu HH; Department of Thoracic Surgery, Tainan Municipal Hospital, Tainan, Taiwan, R.O.C., Hsieh PF; Department of Urology, E-Da Hospital, Kaohsiung, Taiwan, R.O.C.; Department of Medical Laboratory Science and Biotechnology, Chung-Hwa University of Medical Technology, Tainan, Taiwan, R.O.C., Shi MD; Department of Medical Laboratory Science, Chest Hospital, Ministry of Health and Welfare, Tainan, Taiwan, R.O.C., Ko CH; Department of Family Medicine, Chi-Mei Hospital, Tainan, Taiwan, R.O.C.; Department of Food Nutrition, Chung-Hwa University of Medical Technology, Tainan, Taiwan, R.O.C., Wu CH; Department of Urology, E-Da Hospital, Kaohsiung, Taiwan, R.O.C.; Division of Urology, Department of Surgery, E-Da Hospital, Kaohsiung, Taiwan, R.O.C.; Department of Chemical Engineering and Institute of Biotechnology and Chemical Engineering, I-Shou University, Kaohsiung, Taiwan, R.O.C.; Department of Nursing, I-Shou University, Kaohsiung, Taiwan, R.O.C., Lin VC; Department of Urology, E-Da Hospital, Kaohsiung, Taiwan, R.O.C.; School of Medicine, College of Medicine, I-Shou University, Kaohsiung, Taiwan, R.O.C., Liu SF; Department of Internal Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan, R.O.C., Hung YJ; Department of Nursing, Chung-Hwa University of Medical Technology, Tainan, Taiwan, R.O.C., Hung TS; Department of Sports, Health and Leisure, Chung-Hwa University of Medical Technology, Tainan, Taiwan, R.O.C., Wang IC; Department of Rehabilitation, Tainan Branch, Kaohsiung Veterans General Hospital, Tainan, Taiwan, R.O.C.; yulin@mail.hwai.edu.tw bm840000@mail.vhyk.gov.tw.; Department of Food Nutrition, Chung-Hwa University of Medical Technology, Tainan, Taiwan, R.O.C., Yang YL; Department of Medical Laboratory Science and Biotechnology, Chung-Hwa University of Medical Technology, Tainan, Taiwan, R.O.C.; yulin@mail.hwai.edu.tw bm840000@mail.vhyk.gov.tw.; Graduate Institute of Biological Science and Technology, Chung-Hwa College of Medical Technology, Tainan, Taiwan, R.O.C.
Source: Cancer genomics & proteomics [Cancer Genomics Proteomics] 2026 Jul-Aug; Vol. 23 (4), pp. 806-823.
Publication Type: Journal Article
Journal Info: Publisher: International Institute of Anticancer Research Country of Publication: Greece NLM ID: 101188791 Publication Model: Print Cited Medium: Internet ISSN: 1790-6245 (Electronic) Linking ISSN: 11096535 NLM ISO Abbreviation: Cancer Genomics Proteomics Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: NRF1 Activates the AMPK/SIRT1/PGC-1α/TFAM Axis to Suppress EMT and Tumor Progression in Lung Adenocarcinoma.
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  Data: <searchLink fieldCode="AU" term="%22Wu+HH%22">Wu HH</searchLink>; Department of Thoracic Surgery, Tainan Municipal Hospital, Tainan, Taiwan, R.O.C.<br /><searchLink fieldCode="AU" term="%22Hsieh+PF%22">Hsieh PF</searchLink>; Department of Urology, E-Da Hospital, Kaohsiung, Taiwan, R.O.C.; Department of Medical Laboratory Science and Biotechnology, Chung-Hwa University of Medical Technology, Tainan, Taiwan, R.O.C.<br /><searchLink fieldCode="AU" term="%22Shi+MD%22">Shi MD</searchLink>; Department of Medical Laboratory Science, Chest Hospital, Ministry of Health and Welfare, Tainan, Taiwan, R.O.C.<br /><searchLink fieldCode="AU" term="%22Ko+CH%22">Ko CH</searchLink>; Department of Family Medicine, Chi-Mei Hospital, Tainan, Taiwan, R.O.C.; Department of Food Nutrition, Chung-Hwa University of Medical Technology, Tainan, Taiwan, R.O.C.<br /><searchLink fieldCode="AU" term="%22Wu+CH%22">Wu CH</searchLink>; Department of Urology, E-Da Hospital, Kaohsiung, Taiwan, R.O.C.; Division of Urology, Department of Surgery, E-Da Hospital, Kaohsiung, Taiwan, R.O.C.; Department of Chemical Engineering and Institute of Biotechnology and Chemical Engineering, I-Shou University, Kaohsiung, Taiwan, R.O.C.; Department of Nursing, I-Shou University, Kaohsiung, Taiwan, R.O.C.<br /><searchLink fieldCode="AU" term="%22Lin+VC%22">Lin VC</searchLink>; Department of Urology, E-Da Hospital, Kaohsiung, Taiwan, R.O.C.; School of Medicine, College of Medicine, I-Shou University, Kaohsiung, Taiwan, R.O.C.<br /><searchLink fieldCode="AU" term="%22Liu+SF%22">Liu SF</searchLink>; Department of Internal Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan, R.O.C.<br /><searchLink fieldCode="AU" term="%22Hung+YJ%22">Hung YJ</searchLink>; Department of Nursing, Chung-Hwa University of Medical Technology, Tainan, Taiwan, R.O.C.<br /><searchLink fieldCode="AU" term="%22Hung+TS%22">Hung TS</searchLink>; Department of Sports, Health and Leisure, Chung-Hwa University of Medical Technology, Tainan, Taiwan, R.O.C.<br /><searchLink fieldCode="AU" term="%22Wang+IC%22">Wang IC</searchLink>; Department of Rehabilitation, Tainan Branch, Kaohsiung Veterans General Hospital, Tainan, Taiwan, R.O.C.; yulin@mail.hwai.edu.tw bm840000@mail.vhyk.gov.tw.; Department of Food Nutrition, Chung-Hwa University of Medical Technology, Tainan, Taiwan, R.O.C.<br /><searchLink fieldCode="AU" term="%22Yang+YL%22">Yang YL</searchLink>; Department of Medical Laboratory Science and Biotechnology, Chung-Hwa University of Medical Technology, Tainan, Taiwan, R.O.C.; yulin@mail.hwai.edu.tw bm840000@mail.vhyk.gov.tw.; Graduate Institute of Biological Science and Technology, Chung-Hwa College of Medical Technology, Tainan, Taiwan, R.O.C.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22International+Institute+of+Anticancer+Research%22">International Institute of Anticancer Research </searchLink><i>Country of Publication: </i>Greece <i>NLM ID: </i>101188791 <i>Publication Model: </i>Print <i>Cited Medium: </i>Internet <i>ISSN: </i>1790-6245 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2211096535%22">11096535 </searchLink><i>NLM ISO Abbreviation: </i>Cancer Genomics Proteomics <i>Subsets: </i>MEDLINE
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        Value: 10.21873/cgp.20602
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        Text: English
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      – TitleFull: NRF1 Activates the AMPK/SIRT1/PGC-1α/TFAM Axis to Suppress EMT and Tumor Progression in Lung Adenocarcinoma.
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            – D: 01
              M: 07
              Text: 2026 Jul-Aug
              Type: published
              Y: 2026
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