Outcomes of patients with higher-risk myelodysplastic syndromes/neoplasms treated with hypomethylating agents + venetoclax-an analysis from the International Consortium for MDS (icMDS) VALIDATE database.

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Title: Outcomes of patients with higher-risk myelodysplastic syndromes/neoplasms treated with hypomethylating agents + venetoclax-an analysis from the International Consortium for MDS (icMDS) VALIDATE database.
Authors: Bewersdorf JP; Section of Medical Oncology and Hematology, Department of Internal Medicine, Yale University, and Yale Comprehensive Cancer Center, New Haven, CT, USA., Kewan T; Section of Medical Oncology and Hematology, Department of Internal Medicine, Yale University, and Yale Comprehensive Cancer Center, New Haven, CT, USA., Lanino L; Section of Medical Oncology and Hematology, Department of Internal Medicine, Yale University, and Yale Comprehensive Cancer Center, New Haven, CT, USA., Wei W; Department of Internal Medicine, Yale Cancer Center, Yale School of Medicine, New Haven, CT, USA., Rudra Gupta T; Department of Internal Medicine, Yale Cancer Center, Yale School of Medicine, New Haven, CT, USA., Stempel JM; Section of Medical Oncology and Hematology, Department of Internal Medicine, Yale University, and Yale Comprehensive Cancer Center, New Haven, CT, USA., Al Ali NH; Department of Malignant Hematology, H. Lee Moffitt Cancer Center, Tampa, FL, USA., DeZern AE; Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University, Baltimore, MD, USA., Sekeres MA; Sylvester Comprehensive Cancer Center, University of Miami Miller School of Medicine, Miami, FL, USA., Uy GL; Washington University School of Medicine, Saint Louis, MO, USA., Urrutia S; Washington University School of Medicine, Saint Louis, MO, USA., Carraway HE; Department of Hematology and Medical Oncology, Taussig Cancer Institute, Leukemia Program, Cleveland Clinic, Cleveland, OH, USA., Desai P; Weill Cornell Medicine, New York City, NY, USA., Griffiths EA; Roswell Park Comprehensive Cancer Center, Buffalo, NY, USA., Stein EM; Department of Medicine, Leukemia Service, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Brunner AM; Division of Hematology/Oncology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA., McMahon C; University of Colorado, Aurora, CO, USA., Shallis RM; Department of Malignant Hematology, H. Lee Moffitt Cancer Center, Tampa, FL, USA., Zeidner JF; University of North Carolina, Lineberger Comprehensive Cancer Center, Chapel Hill, NC, USA., Savona MR; Vanderbilt-Ingram Cancer Center, Vanderbilt University Medical Center, Nashville, TN, USA., Hawkins H; Vanderbilt-Ingram Cancer Center, Vanderbilt University Medical Center, Nashville, TN, USA., Chandhok NS; Sylvester Comprehensive Cancer Center, University of Miami Miller School of Medicine, Miami, FL, USA., Logothetis CN; Washington University School of Medicine, Saint Louis, MO, USA., Bidikian A; Section of Medical Oncology and Hematology, Department of Internal Medicine, Yale University, and Yale Comprehensive Cancer Center, New Haven, CT, USA., Getz TM; Section of Medical Oncology and Hematology, Department of Internal Medicine, Yale University, and Yale Comprehensive Cancer Center, New Haven, CT, USA., Roboz GJ; Weill Cornell Medicine, New York City, NY, USA., Rolles B; Section of Medical Oncology and Hematology, Department of Internal Medicine, Yale University, and Yale Comprehensive Cancer Center, New Haven, CT, USA.; Division of Hematology, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.; Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA, USA., Wang ES; Roswell Park Comprehensive Cancer Center, Buffalo, NY, USA., Harris AC; Division of Hematology/Oncology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA., Amaya ML; University of Colorado, Aurora, CO, USA., Ball S; Vanderbilt-Ingram Cancer Center, Vanderbilt University Medical Center, Nashville, TN, USA., Grenet J; Weill Cornell Medicine, New York City, NY, USA., Xie Z; Department of Malignant Hematology, H. Lee Moffitt Cancer Center, Tampa, FL, USA., Madanat YF; Harold C. Simmons Comprehensive Cancer Center, UT Southwestern Medical Center, Dallas, TX, USA., Abaza Y; Northwestern University, Chicago, IL, USA., Badar T; Division of Hematology-Oncology, Mayo Clinic, Jacksonville, FL, USA., Campos J; Division of Hematology-Oncology, Mayo Clinic, Jacksonville, FL, USA., Haferlach T; MLL Munich Leukemia Laboratory, Munich, Germany., Maciejewski JP; Department of Hematology and Medical Oncology, Taussig Cancer Institute, Leukemia Program, Cleveland Clinic, Cleveland, OH, USA., Sallman D; Department of Malignant Hematology, H. Lee Moffitt Cancer Center, Tampa, FL, USA., Enjeti A; Department of Haematology, Calvary Mater Hospital, Newcastle, NSW, Australia., Al-Rabi K; King Hussein Cancer Center, Amman, Jordan., Halahleh K; King Hussein Cancer Center, Amman, Jordan., Hiwase D; Department of Haematology, The Royal Adelaide Hospital, Adelaide, SA, Australia., Diez-Campelo M; Hematology Department, Institute of Biomedical Research of Salamanca, University Hospital of Salamanca, Salamanca, Spain., Valcarcel D; Department of Hematology and Oncology, University Hospital Vall d'Hebron, Barcelona, Spain., Haferlach C; MLL Munich Leukemia Laboratory, Munich, Germany., Pleyer L; 3rd Medical Department with Hematology, Medical Oncology, Hemostaseology, Rheumatology and Infectiology, Oncologic Center, Paracelsus Medical University, Salzburg, Austria., Kotsianidis I; Department of Hematology, Democritus University of Thrace Medical School, Alexandroupolis, Greece., Pappa V; Hematology Division, Second Department of Internal Medicine, Attikon University Hospital, National and Kapodistrian University of Athens, Athens, Greece., Santini V; MDS Unit, Hematology, AOU Careggi-Department of Experimental and Clinical Medicine, University of Florence, Florence, Italy., Consagra A; MDS Unit, Hematology, AOU Careggi-Department of Experimental and Clinical Medicine, University of Florence, Florence, Italy., Al-Kali A; Mayo Clinic, Rochester, MN, USA., Ogawa S; Department of Pathology and Tumor Biology, Institute for the Advanced Study of Human Biology (WPI-ASHBi), Kyoto University, Kyoto, Japan.; Department of Innovative Medicine, Faculty of Medicine, Kindai University, Osaka, Japan., Nannya Y; Institute of Medical Science, The University of Tokyo, Tokyo, Japan., Stahl M; Section of Medical Oncology and Hematology, Department of Internal Medicine, Yale University, and Yale Comprehensive Cancer Center, New Haven, CT, USA.; Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA, USA., Della Porta MG; IRCCS Humanitas Research Hospital and Department of Biomedical Sciences, Humanitas University, Milan, Italy., Komrokji RS; Department of Malignant Hematology, H. Lee Moffitt Cancer Center, Tampa, FL, USA., Zeidan AM; Section of Medical Oncology and Hematology, Department of Internal Medicine, Yale University, and Yale Comprehensive Cancer Center, New Haven, CT, USA. amer.zeidan@yale.edu.
Source: Blood cancer journal [Blood Cancer J] 2026 Jun 29. Date of Electronic Publication: 2026 Jun 29.
Publication Type: Journal Article
Journal Info: Publisher: Nature Pub. Group Country of Publication: United States NLM ID: 101568469 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2044-5385 (Electronic) Linking ISSN: 20445385 NLM ISO Abbreviation: Blood Cancer J Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:2044-5385
DOI:10.1038/s41408-026-01543-6