Outcomes of patients with higher-risk myelodysplastic syndromes/neoplasms treated with hypomethylating agents + venetoclax-an analysis from the International Consortium for MDS (icMDS) VALIDATE database.
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| Title: | Outcomes of patients with higher-risk myelodysplastic syndromes/neoplasms treated with hypomethylating agents + venetoclax-an analysis from the International Consortium for MDS (icMDS) VALIDATE database. |
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| Authors: | Bewersdorf JP; Section of Medical Oncology and Hematology, Department of Internal Medicine, Yale University, and Yale Comprehensive Cancer Center, New Haven, CT, USA., Kewan T; Section of Medical Oncology and Hematology, Department of Internal Medicine, Yale University, and Yale Comprehensive Cancer Center, New Haven, CT, USA., Lanino L; Section of Medical Oncology and Hematology, Department of Internal Medicine, Yale University, and Yale Comprehensive Cancer Center, New Haven, CT, USA., Wei W; Department of Internal Medicine, Yale Cancer Center, Yale School of Medicine, New Haven, CT, USA., Rudra Gupta T; Department of Internal Medicine, Yale Cancer Center, Yale School of Medicine, New Haven, CT, USA., Stempel JM; Section of Medical Oncology and Hematology, Department of Internal Medicine, Yale University, and Yale Comprehensive Cancer Center, New Haven, CT, USA., Al Ali NH; Department of Malignant Hematology, H. Lee Moffitt Cancer Center, Tampa, FL, USA., DeZern AE; Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University, Baltimore, MD, USA., Sekeres MA; Sylvester Comprehensive Cancer Center, University of Miami Miller School of Medicine, Miami, FL, USA., Uy GL; Washington University School of Medicine, Saint Louis, MO, USA., Urrutia S; Washington University School of Medicine, Saint Louis, MO, USA., Carraway HE; Department of Hematology and Medical Oncology, Taussig Cancer Institute, Leukemia Program, Cleveland Clinic, Cleveland, OH, USA., Desai P; Weill Cornell Medicine, New York City, NY, USA., Griffiths EA; Roswell Park Comprehensive Cancer Center, Buffalo, NY, USA., Stein EM; Department of Medicine, Leukemia Service, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Brunner AM; Division of Hematology/Oncology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA., McMahon C; University of Colorado, Aurora, CO, USA., Shallis RM; Department of Malignant Hematology, H. Lee Moffitt Cancer Center, Tampa, FL, USA., Zeidner JF; University of North Carolina, Lineberger Comprehensive Cancer Center, Chapel Hill, NC, USA., Savona MR; Vanderbilt-Ingram Cancer Center, Vanderbilt University Medical Center, Nashville, TN, USA., Hawkins H; Vanderbilt-Ingram Cancer Center, Vanderbilt University Medical Center, Nashville, TN, USA., Chandhok NS; Sylvester Comprehensive Cancer Center, University of Miami Miller School of Medicine, Miami, FL, USA., Logothetis CN; Washington University School of Medicine, Saint Louis, MO, USA., Bidikian A; Section of Medical Oncology and Hematology, Department of Internal Medicine, Yale University, and Yale Comprehensive Cancer Center, New Haven, CT, USA., Getz TM; Section of Medical Oncology and Hematology, Department of Internal Medicine, Yale University, and Yale Comprehensive Cancer Center, New Haven, CT, USA., Roboz GJ; Weill Cornell Medicine, New York City, NY, USA., Rolles B; Section of Medical Oncology and Hematology, Department of Internal Medicine, Yale University, and Yale Comprehensive Cancer Center, New Haven, CT, USA.; Division of Hematology, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.; Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA, USA., Wang ES; Roswell Park Comprehensive Cancer Center, Buffalo, NY, USA., Harris AC; Division of Hematology/Oncology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA., Amaya ML; University of Colorado, Aurora, CO, USA., Ball S; Vanderbilt-Ingram Cancer Center, Vanderbilt University Medical Center, Nashville, TN, USA., Grenet J; Weill Cornell Medicine, New York City, NY, USA., Xie Z; Department of Malignant Hematology, H. Lee Moffitt Cancer Center, Tampa, FL, USA., Madanat YF; Harold C. Simmons Comprehensive Cancer Center, UT Southwestern Medical Center, Dallas, TX, USA., Abaza Y; Northwestern University, Chicago, IL, USA., Badar T; Division of Hematology-Oncology, Mayo Clinic, Jacksonville, FL, USA., Campos J; Division of Hematology-Oncology, Mayo Clinic, Jacksonville, FL, USA., Haferlach T; MLL Munich Leukemia Laboratory, Munich, Germany., Maciejewski JP; Department of Hematology and Medical Oncology, Taussig Cancer Institute, Leukemia Program, Cleveland Clinic, Cleveland, OH, USA., Sallman D; Department of Malignant Hematology, H. Lee Moffitt Cancer Center, Tampa, FL, USA., Enjeti A; Department of Haematology, Calvary Mater Hospital, Newcastle, NSW, Australia., Al-Rabi K; King Hussein Cancer Center, Amman, Jordan., Halahleh K; King Hussein Cancer Center, Amman, Jordan., Hiwase D; Department of Haematology, The Royal Adelaide Hospital, Adelaide, SA, Australia., Diez-Campelo M; Hematology Department, Institute of Biomedical Research of Salamanca, University Hospital of Salamanca, Salamanca, Spain., Valcarcel D; Department of Hematology and Oncology, University Hospital Vall d'Hebron, Barcelona, Spain., Haferlach C; MLL Munich Leukemia Laboratory, Munich, Germany., Pleyer L; 3rd Medical Department with Hematology, Medical Oncology, Hemostaseology, Rheumatology and Infectiology, Oncologic Center, Paracelsus Medical University, Salzburg, Austria., Kotsianidis I; Department of Hematology, Democritus University of Thrace Medical School, Alexandroupolis, Greece., Pappa V; Hematology Division, Second Department of Internal Medicine, Attikon University Hospital, National and Kapodistrian University of Athens, Athens, Greece., Santini V; MDS Unit, Hematology, AOU Careggi-Department of Experimental and Clinical Medicine, University of Florence, Florence, Italy., Consagra A; MDS Unit, Hematology, AOU Careggi-Department of Experimental and Clinical Medicine, University of Florence, Florence, Italy., Al-Kali A; Mayo Clinic, Rochester, MN, USA., Ogawa S; Department of Pathology and Tumor Biology, Institute for the Advanced Study of Human Biology (WPI-ASHBi), Kyoto University, Kyoto, Japan.; Department of Innovative Medicine, Faculty of Medicine, Kindai University, Osaka, Japan., Nannya Y; Institute of Medical Science, The University of Tokyo, Tokyo, Japan., Stahl M; Section of Medical Oncology and Hematology, Department of Internal Medicine, Yale University, and Yale Comprehensive Cancer Center, New Haven, CT, USA.; Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA, USA., Della Porta MG; IRCCS Humanitas Research Hospital and Department of Biomedical Sciences, Humanitas University, Milan, Italy., Komrokji RS; Department of Malignant Hematology, H. Lee Moffitt Cancer Center, Tampa, FL, USA., Zeidan AM; Section of Medical Oncology and Hematology, Department of Internal Medicine, Yale University, and Yale Comprehensive Cancer Center, New Haven, CT, USA. amer.zeidan@yale.edu. |
| Source: | Blood cancer journal [Blood Cancer J] 2026 Jun 29. Date of Electronic Publication: 2026 Jun 29. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Nature Pub. Group Country of Publication: United States NLM ID: 101568469 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2044-5385 (Electronic) Linking ISSN: 20445385 NLM ISO Abbreviation: Blood Cancer J Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
| FullText | Text: Availability: 0 |
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| Header | DbId: mdl DbLabel: MEDLINE Ultimate An: 42373605 AccessLevel: 2 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: Outcomes of patients with higher-risk myelodysplastic syndromes/neoplasms treated with hypomethylating agents + venetoclax-an analysis from the International Consortium for MDS (icMDS) VALIDATE database. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AU" term="%22Bewersdorf+JP%22">Bewersdorf JP</searchLink>; Section of Medical Oncology and Hematology, Department of Internal Medicine, Yale University, and Yale Comprehensive Cancer Center, New Haven, CT, USA.<br /><searchLink fieldCode="AU" term="%22Kewan+T%22">Kewan T</searchLink>; Section of Medical Oncology and Hematology, Department of Internal Medicine, Yale University, and Yale Comprehensive Cancer Center, New Haven, CT, USA.<br /><searchLink fieldCode="AU" term="%22Lanino+L%22">Lanino L</searchLink>; Section of Medical Oncology and Hematology, Department of Internal Medicine, Yale University, and Yale Comprehensive Cancer Center, New Haven, CT, USA.<br /><searchLink fieldCode="AU" term="%22Wei+W%22">Wei W</searchLink>; Department of Internal Medicine, Yale Cancer Center, Yale School of Medicine, New Haven, CT, USA.<br /><searchLink fieldCode="AU" term="%22Rudra+Gupta+T%22">Rudra Gupta T</searchLink>; Department of Internal Medicine, Yale Cancer Center, Yale School of Medicine, New Haven, CT, USA.<br /><searchLink fieldCode="AU" term="%22Stempel+JM%22">Stempel JM</searchLink>; Section of Medical Oncology and Hematology, Department of Internal Medicine, Yale University, and Yale Comprehensive Cancer Center, New Haven, CT, USA.<br /><searchLink fieldCode="AU" term="%22Al+Ali+NH%22">Al Ali NH</searchLink>; Department of Malignant Hematology, H. Lee Moffitt Cancer Center, Tampa, FL, USA.<br /><searchLink fieldCode="AU" term="%22DeZern+AE%22">DeZern AE</searchLink>; Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University, Baltimore, MD, USA.<br /><searchLink fieldCode="AU" term="%22Sekeres+MA%22">Sekeres MA</searchLink>; Sylvester Comprehensive Cancer Center, University of Miami Miller School of Medicine, Miami, FL, USA.<br /><searchLink fieldCode="AU" term="%22Uy+GL%22">Uy GL</searchLink>; Washington University School of Medicine, Saint Louis, MO, USA.<br /><searchLink fieldCode="AU" term="%22Urrutia+S%22">Urrutia S</searchLink>; Washington University School of Medicine, Saint Louis, MO, USA.<br /><searchLink fieldCode="AU" term="%22Carraway+HE%22">Carraway HE</searchLink>; Department of Hematology and Medical Oncology, Taussig Cancer Institute, Leukemia Program, Cleveland Clinic, Cleveland, OH, USA.<br /><searchLink fieldCode="AU" term="%22Desai+P%22">Desai P</searchLink>; Weill Cornell Medicine, New York City, NY, USA.<br /><searchLink fieldCode="AU" term="%22Griffiths+EA%22">Griffiths EA</searchLink>; Roswell Park Comprehensive Cancer Center, Buffalo, NY, USA.<br /><searchLink fieldCode="AU" term="%22Stein+EM%22">Stein EM</searchLink>; Department of Medicine, Leukemia Service, Memorial Sloan Kettering Cancer Center, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Brunner+AM%22">Brunner AM</searchLink>; Division of Hematology/Oncology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22McMahon+C%22">McMahon C</searchLink>; University of Colorado, Aurora, CO, USA.<br /><searchLink fieldCode="AU" term="%22Shallis+RM%22">Shallis RM</searchLink>; Department of Malignant Hematology, H. Lee Moffitt Cancer Center, Tampa, FL, USA.<br /><searchLink fieldCode="AU" term="%22Zeidner+JF%22">Zeidner JF</searchLink>; University of North Carolina, Lineberger Comprehensive Cancer Center, Chapel Hill, NC, USA.<br /><searchLink fieldCode="AU" term="%22Savona+MR%22">Savona MR</searchLink>; Vanderbilt-Ingram Cancer Center, Vanderbilt University Medical Center, Nashville, TN, USA.<br /><searchLink fieldCode="AU" term="%22Hawkins+H%22">Hawkins H</searchLink>; Vanderbilt-Ingram Cancer Center, Vanderbilt University Medical Center, Nashville, TN, USA.<br /><searchLink fieldCode="AU" term="%22Chandhok+NS%22">Chandhok NS</searchLink>; Sylvester Comprehensive Cancer Center, University of Miami Miller School of Medicine, Miami, FL, USA.<br /><searchLink fieldCode="AU" term="%22Logothetis+CN%22">Logothetis CN</searchLink>; Washington University School of Medicine, Saint Louis, MO, USA.<br /><searchLink fieldCode="AU" term="%22Bidikian+A%22">Bidikian A</searchLink>; Section of Medical Oncology and Hematology, Department of Internal Medicine, Yale University, and Yale Comprehensive Cancer Center, New Haven, CT, USA.<br /><searchLink fieldCode="AU" term="%22Getz+TM%22">Getz TM</searchLink>; Section of Medical Oncology and Hematology, Department of Internal Medicine, Yale University, and Yale Comprehensive Cancer Center, New Haven, CT, USA.<br /><searchLink fieldCode="AU" term="%22Roboz+GJ%22">Roboz GJ</searchLink>; Weill Cornell Medicine, New York City, NY, USA.<br /><searchLink fieldCode="AU" term="%22Rolles+B%22">Rolles B</searchLink>; Section of Medical Oncology and Hematology, Department of Internal Medicine, Yale University, and Yale Comprehensive Cancer Center, New Haven, CT, USA.; Division of Hematology, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.; Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Wang+ES%22">Wang ES</searchLink>; Roswell Park Comprehensive Cancer Center, Buffalo, NY, USA.<br /><searchLink fieldCode="AU" term="%22Harris+AC%22">Harris AC</searchLink>; Division of Hematology/Oncology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Amaya+ML%22">Amaya ML</searchLink>; University of Colorado, Aurora, CO, USA.<br /><searchLink fieldCode="AU" term="%22Ball+S%22">Ball S</searchLink>; Vanderbilt-Ingram Cancer Center, Vanderbilt University Medical Center, Nashville, TN, USA.<br /><searchLink fieldCode="AU" term="%22Grenet+J%22">Grenet J</searchLink>; Weill Cornell Medicine, New York City, NY, USA.<br /><searchLink fieldCode="AU" term="%22Xie+Z%22">Xie Z</searchLink>; Department of Malignant Hematology, H. Lee Moffitt Cancer Center, Tampa, FL, USA.<br /><searchLink fieldCode="AU" term="%22Madanat+YF%22">Madanat YF</searchLink>; Harold C. Simmons Comprehensive Cancer Center, UT Southwestern Medical Center, Dallas, TX, USA.<br /><searchLink fieldCode="AU" term="%22Abaza+Y%22">Abaza Y</searchLink>; Northwestern University, Chicago, IL, USA.<br /><searchLink fieldCode="AU" term="%22Badar+T%22">Badar T</searchLink>; Division of Hematology-Oncology, Mayo Clinic, Jacksonville, FL, USA.<br /><searchLink fieldCode="AU" term="%22Campos+J%22">Campos J</searchLink>; Division of Hematology-Oncology, Mayo Clinic, Jacksonville, FL, USA.<br /><searchLink fieldCode="AU" term="%22Haferlach+T%22">Haferlach T</searchLink>; MLL Munich Leukemia Laboratory, Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Maciejewski+JP%22">Maciejewski JP</searchLink>; Department of Hematology and Medical Oncology, Taussig Cancer Institute, Leukemia Program, Cleveland Clinic, Cleveland, OH, USA.<br /><searchLink fieldCode="AU" term="%22Sallman+D%22">Sallman D</searchLink>; Department of Malignant Hematology, H. Lee Moffitt Cancer Center, Tampa, FL, USA.<br /><searchLink fieldCode="AU" term="%22Enjeti+A%22">Enjeti A</searchLink>; Department of Haematology, Calvary Mater Hospital, Newcastle, NSW, Australia.<br /><searchLink fieldCode="AU" term="%22Al-Rabi+K%22">Al-Rabi K</searchLink>; King Hussein Cancer Center, Amman, Jordan.<br /><searchLink fieldCode="AU" term="%22Halahleh+K%22">Halahleh K</searchLink>; King Hussein Cancer Center, Amman, Jordan.<br /><searchLink fieldCode="AU" term="%22Hiwase+D%22">Hiwase D</searchLink>; Department of Haematology, The Royal Adelaide Hospital, Adelaide, SA, Australia.<br /><searchLink fieldCode="AU" term="%22Diez-Campelo+M%22">Diez-Campelo M</searchLink>; Hematology Department, Institute of Biomedical Research of Salamanca, University Hospital of Salamanca, Salamanca, Spain.<br /><searchLink fieldCode="AU" term="%22Valcarcel+D%22">Valcarcel D</searchLink>; Department of Hematology and Oncology, University Hospital Vall d'Hebron, Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Haferlach+C%22">Haferlach C</searchLink>; MLL Munich Leukemia Laboratory, Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Pleyer+L%22">Pleyer L</searchLink>; 3rd Medical Department with Hematology, Medical Oncology, Hemostaseology, Rheumatology and Infectiology, Oncologic Center, Paracelsus Medical University, Salzburg, Austria.<br /><searchLink fieldCode="AU" term="%22Kotsianidis+I%22">Kotsianidis I</searchLink>; Department of Hematology, Democritus University of Thrace Medical School, Alexandroupolis, Greece.<br /><searchLink fieldCode="AU" term="%22Pappa+V%22">Pappa V</searchLink>; Hematology Division, Second Department of Internal Medicine, Attikon University Hospital, National and Kapodistrian University of Athens, Athens, Greece.<br /><searchLink fieldCode="AU" term="%22Santini+V%22">Santini V</searchLink>; MDS Unit, Hematology, AOU Careggi-Department of Experimental and Clinical Medicine, University of Florence, Florence, Italy.<br /><searchLink fieldCode="AU" term="%22Consagra+A%22">Consagra A</searchLink>; MDS Unit, Hematology, AOU Careggi-Department of Experimental and Clinical Medicine, University of Florence, Florence, Italy.<br /><searchLink fieldCode="AU" term="%22Al-Kali+A%22">Al-Kali A</searchLink>; Mayo Clinic, Rochester, MN, USA.<br /><searchLink fieldCode="AU" term="%22Ogawa+S%22">Ogawa S</searchLink>; Department of Pathology and Tumor Biology, Institute for the Advanced Study of Human Biology (WPI-ASHBi), Kyoto University, Kyoto, Japan.; Department of Innovative Medicine, Faculty of Medicine, Kindai University, Osaka, Japan.<br /><searchLink fieldCode="AU" term="%22Nannya+Y%22">Nannya Y</searchLink>; Institute of Medical Science, The University of Tokyo, Tokyo, Japan.<br /><searchLink fieldCode="AU" term="%22Stahl+M%22">Stahl M</searchLink>; Section of Medical Oncology and Hematology, Department of Internal Medicine, Yale University, and Yale Comprehensive Cancer Center, New Haven, CT, USA.; Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Della+Porta+MG%22">Della Porta MG</searchLink>; IRCCS Humanitas Research Hospital and Department of Biomedical Sciences, Humanitas University, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Komrokji+RS%22">Komrokji RS</searchLink>; Department of Malignant Hematology, H. Lee Moffitt Cancer Center, Tampa, FL, USA.<br /><searchLink fieldCode="AU" term="%22Zeidan+AM%22">Zeidan AM</searchLink>; Section of Medical Oncology and Hematology, Department of Internal Medicine, Yale University, and Yale Comprehensive Cancer Center, New Haven, CT, USA. amer.zeidan@yale.edu. – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%22101568469%22">Blood cancer journal</searchLink> [Blood Cancer J] 2026 Jun 29. <i>Date of Electronic Publication: </i>2026 Jun 29. – Name: TypePub Label: Publication Type Group: TypPub Data: Journal Article – Name: TitleSource Label: Journal Info Group: Src Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Nature+Pub%2E+Group%22">Nature Pub. Group </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>101568469 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>2044-5385 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2220445385%22">20445385 </searchLink><i>NLM ISO Abbreviation: </i>Blood Cancer J <i>Subsets: </i>MEDLINE |
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