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Metagenomic next-generation sequencing of cerebrospinal fluid reveals pathogen spectrum and mortality predictors among patients with advanced HIV-1 disease at a tertiary hospital in China.

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Title: Metagenomic next-generation sequencing of cerebrospinal fluid reveals pathogen spectrum and mortality predictors among patients with advanced HIV-1 disease at a tertiary hospital in China.
Authors: Wan LY; Division of Life Sciences and Medicine, The First Affiliated Hospital of USTC, University of Science and Technology of China, Hefei, China.; Senior Department of Infectious Diseases, Chinese PLA General Hospital, National Clinical Research Center for Infectious Diseases, Beijing, China., Zou J; Department of Infectious Disease, The Fourth People's Hospital of Nanning, Nanning, China., Li XM; Senior Department of Infectious Diseases, Chinese PLA General Hospital, National Clinical Research Center for Infectious Diseases, Beijing, China.; Department of Clinical Medicine, Bengbu Medical University, Bengbu, China., Zhao R; Department of Infectious Disease, The Fourth People's Hospital of Nanning, Nanning, China., Yang G; Department of Clinical Laboratory, Chinese PLA General Hospital, Beijing, China., Zhang MY; Senior Department of Infectious Diseases, Chinese PLA General Hospital, National Clinical Research Center for Infectious Diseases, Beijing, China.; The Second School of Clinical Medicine, Southern Medical University, Guangzhou, China., Xiao QY; Department of Infectious Disease, The Fourth People's Hospital of Nanning, Nanning, China., Wei YD; Department of Infectious Disease, The Fourth People's Hospital of Nanning, Nanning, China., Gao JM; Senior Department of Infectious Diseases, Chinese PLA General Hospital, National Clinical Research Center for Infectious Diseases, Beijing, China., Yang BP; Senior Department of Infectious Diseases, Chinese PLA General Hospital, National Clinical Research Center for Infectious Diseases, Beijing, China., Zhang C; Senior Department of Infectious Diseases, Chinese PLA General Hospital, National Clinical Research Center for Infectious Diseases, Beijing, China., Jiao YM; Senior Department of Infectious Diseases, Chinese PLA General Hospital, National Clinical Research Center for Infectious Diseases, Beijing, China., Wang FS; Division of Life Sciences and Medicine, The First Affiliated Hospital of USTC, University of Science and Technology of China, Hefei, China. fswang302@163.com.; Senior Department of Infectious Diseases, Chinese PLA General Hospital, National Clinical Research Center for Infectious Diseases, Beijing, China. fswang302@163.com., Song JW; Senior Department of Infectious Diseases, Chinese PLA General Hospital, National Clinical Research Center for Infectious Diseases, Beijing, China. songjinwenchina@yeah.net.; The Second School of Clinical Medicine, Southern Medical University, Guangzhou, China. songjinwenchina@yeah.net.
Source: Virology journal [Virol J] 2026 Jun 29. Date of Electronic Publication: 2026 Jun 29.
Publication Type: Journal Article
Journal Info: Publisher: BioMed Central Country of Publication: England NLM ID: 101231645 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1743-422X (Electronic) Linking ISSN: 1743422X NLM ISO Abbreviation: Virol J Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1743-422X
DOI:10.1186/s12985-026-03234-x