Multi-omics integration and in vitro validation identify IL4R, IMPA2, and PRR4 as key therapeutic targets in chronic rhinosinusitis with nasal polyps.
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| Title: | Multi-omics integration and in vitro validation identify IL4R, IMPA2, and PRR4 as key therapeutic targets in chronic rhinosinusitis with nasal polyps. |
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| Authors: | Wei B; Department of Otolaryngology Head and Neck Surgery, West China Hospital, Sichuan University, Chengdu, China., Gan W; Department of Otolaryngology Head and Neck Surgery, West China Hospital, Sichuan University, Chengdu, China., Li J; Department of Otolaryngology Head and Neck Surgery, West China Hospital, Sichuan University, Chengdu, China., Wang F; Department of Otolaryngology Head and Neck Surgery, West China Hospital, Sichuan University, Chengdu, China., Wang J; Department of Otolaryngology Head and Neck Surgery, West China Hospital, Sichuan University, Chengdu, China., Wang B; Department of Otolaryngology Head and Neck Surgery, West China Hospital, Sichuan University, Chengdu, China., He J; Renji Medical Research Center, Chengdu Second People's Hospital, Chengdu, China., Liu F; Department of Otolaryngology Head and Neck Surgery, West China Hospital, Sichuan University, Chengdu, China. |
| Source: | Frontiers in immunology [Front Immunol] 2026 Jun 15; Vol. 17, pp. 1792878. Date of Electronic Publication: 2026 Jun 15 (Print Publication: 2026). |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Frontiers Research Foundation] Country of Publication: Switzerland NLM ID: 101560960 Publication Model: eCollection Cited Medium: Internet ISSN: 1664-3224 (Electronic) Linking ISSN: 16643224 NLM ISO Abbreviation: Front Immunol Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 1664-3224 |
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| DOI: | 10.3389/fimmu.2026.1792878 |
