Case Report: Successful treatment of pyoderma gangrenosum-like granulomatous liver disease without skin lesions using a TNF-alpha inhibitor.

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Title: Case Report: Successful treatment of pyoderma gangrenosum-like granulomatous liver disease without skin lesions using a TNF-alpha inhibitor.
Authors: Panne I; University Centre for Gastrointestinal and Liver Diseases, University Hospital, Basel, Switzerland., Matter M; Department of Pathology, University Hospital, Basel, Switzerland., Vosbeck J; Department of Pathology, University Hospital, Basel, Switzerland., von Rotz M; Department of Infectious Diseases, University Hospital, Basel, Switzerland., Steinemann A; Department of Ophthalmology, University Hospital, Basel, Switzerland., Trendelenburg M; University Hospital Basel and Clinical Immunology, Department of Biomedicine, University of Basel, Basel, Switzerland., Heim MH; University Centre for Gastrointestinal and Liver Diseases, University Hospital, Basel, Switzerland.; Departments of Biomedicine and Clinical Research, University of Basel, Basel, Switzerland., Schirmacher P; Department of Pathology, University Hospital Heidelberg, Heidelberg, Germany., De Gottardi A; Gastroenterology and Hepatology, Luzerner Kantonsspital, Luzern, Switzerland.; Università della Svizzera Italiana, Faculty of Biomedical Sciences, Lugano, Switzerland., Lohse AW; Department of Medicine, University Medical Centre Hamburg-Eppendorf, Hamburg, Germany., Terracciano LM; Department of Biomedical Sciences, Humanitas University, Pieve Emanuele, Milan, Italy.; IRCCS Humanitas Research Hospital, Rozzano, Milan, Italy., Bernsmeier C; University Centre for Gastrointestinal and Liver Diseases, University Hospital, Basel, Switzerland.; Departments of Biomedicine and Clinical Research, University of Basel, Basel, Switzerland.
Source: Frontiers in immunology [Front Immunol] 2026 Jun 15; Vol. 17, pp. 1811910. Date of Electronic Publication: 2026 Jun 15 (Print Publication: 2026).
Publication Type: Case Reports; Journal Article
Journal Info: Publisher: Frontiers Research Foundation] Country of Publication: Switzerland NLM ID: 101560960 Publication Model: eCollection Cited Medium: Internet ISSN: 1664-3224 (Electronic) Linking ISSN: 16643224 NLM ISO Abbreviation: Front Immunol Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:1664-3224
DOI:10.3389/fimmu.2026.1811910