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Design, synthesis and biological evaluations of novel VEGFR-2 inhibitors based on Fruquintinib and Cabozantinib.

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Title: Design, synthesis and biological evaluations of novel VEGFR-2 inhibitors based on Fruquintinib and Cabozantinib.
Authors: Ding X; School of Medicine, Huaqiao University, Quanzhou, 362000, China., Wei H; School of Medicine, Huaqiao University, Quanzhou, 362000, China., Ye M; School of Medicine, Huaqiao University, Quanzhou, 362000, China., Huang Y; School of Medicine, Huaqiao University, Quanzhou, 362000, China., Su A; School of Medicine, Huaqiao University, Quanzhou, 362000, China., Ding X; School of Medicine, Huaqiao University, Quanzhou, 362000, China., Chen W; Department of Pharmacy, The Second Affiliated Hospital of Fujian Medical University, Quanzhou, 362000, China. 67942074@qq.com., Tang Z; Department of Endocrinology, Shanghai East Hospital, Shanghai, 200120, China., Ma J; School of Medicine, Huaqiao University, Quanzhou, 362000, China. majunjie3612@hqu.edu.cn.
Source: Molecular diversity [Mol Divers] 2026 Jun 30. Date of Electronic Publication: 2026 Jun 30.
Publication Type: Journal Article
Journal Info: Publisher: ESCOM Science Publishers Country of Publication: Netherlands NLM ID: 9516534 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1573-501X (Electronic) Linking ISSN: 13811991 NLM ISO Abbreviation: Mol Divers Subsets: MEDLINE
Database: MEDLINE Ultimate
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PubType: Academic Journal
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  Data: Design, synthesis and biological evaluations of novel VEGFR-2 inhibitors based on Fruquintinib and Cabozantinib.
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  Data: <searchLink fieldCode="AU" term="%22Ding+X%22">Ding X</searchLink>; School of Medicine, Huaqiao University, Quanzhou, 362000, China.<br /><searchLink fieldCode="AU" term="%22Wei+H%22">Wei H</searchLink>; School of Medicine, Huaqiao University, Quanzhou, 362000, China.<br /><searchLink fieldCode="AU" term="%22Ye+M%22">Ye M</searchLink>; School of Medicine, Huaqiao University, Quanzhou, 362000, China.<br /><searchLink fieldCode="AU" term="%22Huang+Y%22">Huang Y</searchLink>; School of Medicine, Huaqiao University, Quanzhou, 362000, China.<br /><searchLink fieldCode="AU" term="%22Su+A%22">Su A</searchLink>; School of Medicine, Huaqiao University, Quanzhou, 362000, China.<br /><searchLink fieldCode="AU" term="%22Ding+X%22">Ding X</searchLink>; School of Medicine, Huaqiao University, Quanzhou, 362000, China.<br /><searchLink fieldCode="AU" term="%22Chen+W%22">Chen W</searchLink>; Department of Pharmacy, The Second Affiliated Hospital of Fujian Medical University, Quanzhou, 362000, China. 67942074@qq.com.<br /><searchLink fieldCode="AU" term="%22Tang+Z%22">Tang Z</searchLink>; Department of Endocrinology, Shanghai East Hospital, Shanghai, 200120, China.<br /><searchLink fieldCode="AU" term="%22Ma+J%22">Ma J</searchLink>; School of Medicine, Huaqiao University, Quanzhou, 362000, China. majunjie3612@hqu.edu.cn.
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  Data: <searchLink fieldCode="JN" term="%229516534%22">Molecular diversity</searchLink> [Mol Divers] 2026 Jun 30. <i>Date of Electronic Publication: </i>2026 Jun 30.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22ESCOM+Science+Publishers%22">ESCOM Science Publishers </searchLink><i>Country of Publication: </i>Netherlands <i>NLM ID: </i>9516534 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1573-501X (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2213811991%22">13811991 </searchLink><i>NLM ISO Abbreviation: </i>Mol Divers <i>Subsets: </i>MEDLINE
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      – Type: doi
        Value: 10.1007/s11030-026-11628-w
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      – Code: eng
        Text: English
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      – TitleFull: Design, synthesis and biological evaluations of novel VEGFR-2 inhibitors based on Fruquintinib and Cabozantinib.
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            NameFull: Ding X
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            NameFull: Wei H
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            NameFull: Ye M
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            – D: 30
              M: 06
              Text: 2026 Jun 30
              Type: published
              Y: 2026
          Identifiers:
            – Type: issn-electronic
              Value: 1573-501X
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