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Visual uncertainty and task demands shape active sensing strategies in mice.

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Title: Visual uncertainty and task demands shape active sensing strategies in mice.
Authors: Benquet C; EPFL Neuro, School of Life Sciences, EPFL, 1202 Genève, Switzerland., Sainsbury T; EPFL Neuro, School of Life Sciences, EPFL, 1202 Genève, Switzerland., Bruneau L; EPFL Neuro, School of Life Sciences, EPFL, 1202 Genève, Switzerland., Lin Y; Department of Neuroscience, Center for Neuroscience and Artificial Intelligence, Baylor College of Medicine, Houston, TX 77030, USA; Department of Ophthalmology, Byers Eye Institute, Stanford University School of Medicine, Stanford University, Palo Alto, CA 94303, USA; Stanford Bio-X, Wu Tsai Neurosciences Institute, Stanford University, Stanford, CA 94305, USA; Department of Electrical Engineering, Stanford University, Stanford, CA 94305, USA., Cai C; Department of Neuroscience, Center for Neuroscience and Artificial Intelligence, Baylor College of Medicine, Houston, TX 77030, USA; Department of Ophthalmology, Byers Eye Institute, Stanford University School of Medicine, Stanford University, Palo Alto, CA 94303, USA; Stanford Bio-X, Wu Tsai Neurosciences Institute, Stanford University, Stanford, CA 94305, USA; Department of Electrical Engineering, Stanford University, Stanford, CA 94305, USA; Institute for Ophthalmic Research, Tübingen University, 72076 Tübingen, Germany., Popova M; EPFL Neuro, School of Life Sciences, EPFL, 1202 Genève, Switzerland., Ponder K; Department of Neuroscience, Center for Neuroscience and Artificial Intelligence, Baylor College of Medicine, Houston, TX 77030, USA; Department of Ophthalmology, Byers Eye Institute, Stanford University School of Medicine, Stanford University, Palo Alto, CA 94303, USA; Stanford Bio-X, Wu Tsai Neurosciences Institute, Stanford University, Stanford, CA 94305, USA; Department of Electrical Engineering, Stanford University, Stanford, CA 94305, USA., Ntanavara L; Department of Neuroscience, Center for Neuroscience and Artificial Intelligence, Baylor College of Medicine, Houston, TX 77030, USA; Department of Ophthalmology, Byers Eye Institute, Stanford University School of Medicine, Stanford University, Palo Alto, CA 94303, USA; Stanford Bio-X, Wu Tsai Neurosciences Institute, Stanford University, Stanford, CA 94305, USA; Department of Electrical Engineering, Stanford University, Stanford, CA 94305, USA., Froebe R; Department of Neuroscience, Center for Neuroscience and Artificial Intelligence, Baylor College of Medicine, Houston, TX 77030, USA; Department of Ophthalmology, Byers Eye Institute, Stanford University School of Medicine, Stanford University, Palo Alto, CA 94303, USA; Stanford Bio-X, Wu Tsai Neurosciences Institute, Stanford University, Stanford, CA 94305, USA; Department of Electrical Engineering, Stanford University, Stanford, CA 94305, USA., Tan Z; Department of Neuroscience, Center for Neuroscience and Artificial Intelligence, Baylor College of Medicine, Houston, TX 77030, USA; Department of Ophthalmology, Byers Eye Institute, Stanford University School of Medicine, Stanford University, Palo Alto, CA 94303, USA; Stanford Bio-X, Wu Tsai Neurosciences Institute, Stanford University, Stanford, CA 94305, USA; Department of Electrical Engineering, Stanford University, Stanford, CA 94305, USA., Fahey P; Department of Neuroscience, Center for Neuroscience and Artificial Intelligence, Baylor College of Medicine, Houston, TX 77030, USA; Department of Ophthalmology, Byers Eye Institute, Stanford University School of Medicine, Stanford University, Palo Alto, CA 94303, USA; Stanford Bio-X, Wu Tsai Neurosciences Institute, Stanford University, Stanford, CA 94305, USA; Department of Electrical Engineering, Stanford University, Stanford, CA 94305, USA., Franke K; Institute for Ophthalmic Research, Tübingen University, 72076 Tübingen, Germany., Franco LM; Department of Biology and Institute of Neuroscience, University of Oregon, Eugene, OR 97403, USA., Jones K; Department of Biology and Institute of Neuroscience, University of Oregon, Eugene, OR 97403, USA., Chen Y; Neuroscience Institute, Carnegie Mellon University, Pittsburgh, PA 15213, USA., Keller R; Neuroscience Institute, Carnegie Mellon University, Pittsburgh, PA 15213, USA; Robotics Institute, Carnegie Mellon University, Pittsburgh, PA 15213, USA., Pitkow X; Neuroscience Institute, Carnegie Mellon University, Pittsburgh, PA 15213, USA; Machine Learning Department, Carnegie Mellon University, Pittsburgh, PA 15213, USA; Department of Electrical and Computer Engineering, Department of Computer Science, Rice University, Houston, TX 77005, USA; NSF AI Institute for Artificial and Natural Intelligence (ARNI), Columbia Engineering School, New York, NY 10027, USA., Niell CM; Department of Biology and Institute of Neuroscience, University of Oregon, Eugene, OR 97403, USA., Tolias AS; Department of Neuroscience, Center for Neuroscience and Artificial Intelligence, Baylor College of Medicine, Houston, TX 77030, USA; Department of Ophthalmology, Byers Eye Institute, Stanford University School of Medicine, Stanford University, Palo Alto, CA 94303, USA; Stanford Bio-X, Wu Tsai Neurosciences Institute, Stanford University, Stanford, CA 94305, USA; Department of Electrical Engineering, Stanford University, Stanford, CA 94305, USA., Mathis MW; EPFL Neuro, School of Life Sciences, EPFL, 1202 Genève, Switzerland. Electronic address: mackenzie.mathis@epfl.ch.
Source: Current biology : CB [Curr Biol] 2026 Jul 20; Vol. 36 (14), pp. 3523-3534.e9. Date of Electronic Publication: 2026 Jun 30.
Publication Type: Journal Article
Journal Info: Publisher: Cell Press Country of Publication: England NLM ID: 9107782 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-0445 (Electronic) Linking ISSN: 09609822 NLM ISO Abbreviation: Curr Biol Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Visual uncertainty and task demands shape active sensing strategies in mice.
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  Data: <searchLink fieldCode="AU" term="%22Benquet+C%22">Benquet C</searchLink>; EPFL Neuro, School of Life Sciences, EPFL, 1202 Genève, Switzerland.<br /><searchLink fieldCode="AU" term="%22Sainsbury+T%22">Sainsbury T</searchLink>; EPFL Neuro, School of Life Sciences, EPFL, 1202 Genève, Switzerland.<br /><searchLink fieldCode="AU" term="%22Bruneau+L%22">Bruneau L</searchLink>; EPFL Neuro, School of Life Sciences, EPFL, 1202 Genève, Switzerland.<br /><searchLink fieldCode="AU" term="%22Lin+Y%22">Lin Y</searchLink>; Department of Neuroscience, Center for Neuroscience and Artificial Intelligence, Baylor College of Medicine, Houston, TX 77030, USA; Department of Ophthalmology, Byers Eye Institute, Stanford University School of Medicine, Stanford University, Palo Alto, CA 94303, USA; Stanford Bio-X, Wu Tsai Neurosciences Institute, Stanford University, Stanford, CA 94305, USA; Department of Electrical Engineering, Stanford University, Stanford, CA 94305, USA.<br /><searchLink fieldCode="AU" term="%22Cai+C%22">Cai C</searchLink>; Department of Neuroscience, Center for Neuroscience and Artificial Intelligence, Baylor College of Medicine, Houston, TX 77030, USA; Department of Ophthalmology, Byers Eye Institute, Stanford University School of Medicine, Stanford University, Palo Alto, CA 94303, USA; Stanford Bio-X, Wu Tsai Neurosciences Institute, Stanford University, Stanford, CA 94305, USA; Department of Electrical Engineering, Stanford University, Stanford, CA 94305, USA; Institute for Ophthalmic Research, Tübingen University, 72076 Tübingen, Germany.<br /><searchLink fieldCode="AU" term="%22Popova+M%22">Popova M</searchLink>; EPFL Neuro, School of Life Sciences, EPFL, 1202 Genève, Switzerland.<br /><searchLink fieldCode="AU" term="%22Ponder+K%22">Ponder K</searchLink>; Department of Neuroscience, Center for Neuroscience and Artificial Intelligence, Baylor College of Medicine, Houston, TX 77030, USA; Department of Ophthalmology, Byers Eye Institute, Stanford University School of Medicine, Stanford University, Palo Alto, CA 94303, USA; Stanford Bio-X, Wu Tsai Neurosciences Institute, Stanford University, Stanford, CA 94305, USA; Department of Electrical Engineering, Stanford University, Stanford, CA 94305, USA.<br /><searchLink fieldCode="AU" term="%22Ntanavara+L%22">Ntanavara L</searchLink>; Department of Neuroscience, Center for Neuroscience and Artificial Intelligence, Baylor College of Medicine, Houston, TX 77030, USA; Department of Ophthalmology, Byers Eye Institute, Stanford University School of Medicine, Stanford University, Palo Alto, CA 94303, USA; Stanford Bio-X, Wu Tsai Neurosciences Institute, Stanford University, Stanford, CA 94305, USA; Department of Electrical Engineering, Stanford University, Stanford, CA 94305, USA.<br /><searchLink fieldCode="AU" term="%22Froebe+R%22">Froebe R</searchLink>; Department of Neuroscience, Center for Neuroscience and Artificial Intelligence, Baylor College of Medicine, Houston, TX 77030, USA; Department of Ophthalmology, Byers Eye Institute, Stanford University School of Medicine, Stanford University, Palo Alto, CA 94303, USA; Stanford Bio-X, Wu Tsai Neurosciences Institute, Stanford University, Stanford, CA 94305, USA; Department of Electrical Engineering, Stanford University, Stanford, CA 94305, USA.<br /><searchLink fieldCode="AU" term="%22Tan+Z%22">Tan Z</searchLink>; Department of Neuroscience, Center for Neuroscience and Artificial Intelligence, Baylor College of Medicine, Houston, TX 77030, USA; Department of Ophthalmology, Byers Eye Institute, Stanford University School of Medicine, Stanford University, Palo Alto, CA 94303, USA; Stanford Bio-X, Wu Tsai Neurosciences Institute, Stanford University, Stanford, CA 94305, USA; Department of Electrical Engineering, Stanford University, Stanford, CA 94305, USA.<br /><searchLink fieldCode="AU" term="%22Fahey+P%22">Fahey P</searchLink>; Department of Neuroscience, Center for Neuroscience and Artificial Intelligence, Baylor College of Medicine, Houston, TX 77030, USA; Department of Ophthalmology, Byers Eye Institute, Stanford University School of Medicine, Stanford University, Palo Alto, CA 94303, USA; Stanford Bio-X, Wu Tsai Neurosciences Institute, Stanford University, Stanford, CA 94305, USA; Department of Electrical Engineering, Stanford University, Stanford, CA 94305, USA.<br /><searchLink fieldCode="AU" term="%22Franke+K%22">Franke K</searchLink>; Institute for Ophthalmic Research, Tübingen University, 72076 Tübingen, Germany.<br /><searchLink fieldCode="AU" term="%22Franco+LM%22">Franco LM</searchLink>; Department of Biology and Institute of Neuroscience, University of Oregon, Eugene, OR 97403, USA.<br /><searchLink fieldCode="AU" term="%22Jones+K%22">Jones K</searchLink>; Department of Biology and Institute of Neuroscience, University of Oregon, Eugene, OR 97403, USA.<br /><searchLink fieldCode="AU" term="%22Chen+Y%22">Chen Y</searchLink>; Neuroscience Institute, Carnegie Mellon University, Pittsburgh, PA 15213, USA.<br /><searchLink fieldCode="AU" term="%22Keller+R%22">Keller R</searchLink>; Neuroscience Institute, Carnegie Mellon University, Pittsburgh, PA 15213, USA; Robotics Institute, Carnegie Mellon University, Pittsburgh, PA 15213, USA.<br /><searchLink fieldCode="AU" term="%22Pitkow+X%22">Pitkow X</searchLink>; Neuroscience Institute, Carnegie Mellon University, Pittsburgh, PA 15213, USA; Machine Learning Department, Carnegie Mellon University, Pittsburgh, PA 15213, USA; Department of Electrical and Computer Engineering, Department of Computer Science, Rice University, Houston, TX 77005, USA; NSF AI Institute for Artificial and Natural Intelligence (ARNI), Columbia Engineering School, New York, NY 10027, USA.<br /><searchLink fieldCode="AU" term="%22Niell+CM%22">Niell CM</searchLink>; Department of Biology and Institute of Neuroscience, University of Oregon, Eugene, OR 97403, USA.<br /><searchLink fieldCode="AU" term="%22Tolias+AS%22">Tolias AS</searchLink>; Department of Neuroscience, Center for Neuroscience and Artificial Intelligence, Baylor College of Medicine, Houston, TX 77030, USA; Department of Ophthalmology, Byers Eye Institute, Stanford University School of Medicine, Stanford University, Palo Alto, CA 94303, USA; Stanford Bio-X, Wu Tsai Neurosciences Institute, Stanford University, Stanford, CA 94305, USA; Department of Electrical Engineering, Stanford University, Stanford, CA 94305, USA.<br /><searchLink fieldCode="AU" term="%22Mathis+MW%22">Mathis MW</searchLink>; EPFL Neuro, School of Life Sciences, EPFL, 1202 Genève, Switzerland. Electronic address: mackenzie.mathis@epfl.ch.
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  Data: <searchLink fieldCode="JN" term="%229107782%22">Current biology : CB</searchLink> [Curr Biol] 2026 Jul 20; Vol. 36 (14), pp. 3523-3534.e9. <i>Date of Electronic Publication: </i>2026 Jun 30.
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