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Long-term antigen reduction does not achieve durable HBV control in mice but enhances therapeutic vaccine efficacy.

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Title: Long-term antigen reduction does not achieve durable HBV control in mice but enhances therapeutic vaccine efficacy.
Authors: Michler T; Institute of Virology, School of Medicine and Health, Technical University of Munich / Helmholtz Munich; Institute of Laboratory Medicine, LMU University Hospital, LMU Munich., Kosinska A; Institute of Virology, School of Medicine and Health, Technical University of Munich / Helmholtz Munich; German Center for Infection Research (DZIF), Munich partner site., Merdan O; Institute of Virology, School of Medicine and Health, Technical University of Munich / Helmholtz Munich., Hagen P; Institute of Virology, School of Medicine and Health, Technical University of Munich / Helmholtz Munich., Bunse T; Institute of Virology, School of Medicine and Health, Technical University of Munich / Helmholtz Munich., Öz EA; Institute of Virology, School of Medicine and Health, Technical University of Munich / Helmholtz Munich; German Center for Infection Research (DZIF), Munich partner site., Su J; Institute of Virology, School of Medicine and Health, Technical University of Munich / Helmholtz Munich., Busch DH; German Center for Infection Research (DZIF), Munich partner site; Institute of Medical Microbiology, Immunology and Hygiene, School of Medicine and Health, Technical University of Munich., Mogler C; Institute of Pathology, School of Medicine and Health, Technical University of Munich, Munich, Germany., Protzer U; Institute of Virology, School of Medicine and Health, Technical University of Munich / Helmholtz Munich; German Center for Infection Research (DZIF), Munich partner site. Electronic address: protzer@tum.de.
Source: JHEP reports : innovation in hepatology [JHEP Rep] 2026 Jun 30, pp. 101943. Date of Electronic Publication: 2026 Jun 30.
Publication Type: Journal Article
Journal Info: Publisher: Elsevier B.V Country of Publication: Netherlands NLM ID: 101761237 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2589-5559 (Electronic) Linking ISSN: 25895559 NLM ISO Abbreviation: JHEP Rep Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Long-term antigen reduction does not achieve durable HBV control in mice but enhances therapeutic vaccine efficacy.
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  Data: <searchLink fieldCode="AU" term="%22Michler+T%22">Michler T</searchLink>; Institute of Virology, School of Medicine and Health, Technical University of Munich / Helmholtz Munich; Institute of Laboratory Medicine, LMU University Hospital, LMU Munich.<br /><searchLink fieldCode="AU" term="%22Kosinska+A%22">Kosinska A</searchLink>; Institute of Virology, School of Medicine and Health, Technical University of Munich / Helmholtz Munich; German Center for Infection Research (DZIF), Munich partner site.<br /><searchLink fieldCode="AU" term="%22Merdan+O%22">Merdan O</searchLink>; Institute of Virology, School of Medicine and Health, Technical University of Munich / Helmholtz Munich.<br /><searchLink fieldCode="AU" term="%22Hagen+P%22">Hagen P</searchLink>; Institute of Virology, School of Medicine and Health, Technical University of Munich / Helmholtz Munich.<br /><searchLink fieldCode="AU" term="%22Bunse+T%22">Bunse T</searchLink>; Institute of Virology, School of Medicine and Health, Technical University of Munich / Helmholtz Munich.<br /><searchLink fieldCode="AU" term="%22Öz+EA%22">Öz EA</searchLink>; Institute of Virology, School of Medicine and Health, Technical University of Munich / Helmholtz Munich; German Center for Infection Research (DZIF), Munich partner site.<br /><searchLink fieldCode="AU" term="%22Su+J%22">Su J</searchLink>; Institute of Virology, School of Medicine and Health, Technical University of Munich / Helmholtz Munich.<br /><searchLink fieldCode="AU" term="%22Busch+DH%22">Busch DH</searchLink>; German Center for Infection Research (DZIF), Munich partner site; Institute of Medical Microbiology, Immunology and Hygiene, School of Medicine and Health, Technical University of Munich.<br /><searchLink fieldCode="AU" term="%22Mogler+C%22">Mogler C</searchLink>; Institute of Pathology, School of Medicine and Health, Technical University of Munich, Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Protzer+U%22">Protzer U</searchLink>; Institute of Virology, School of Medicine and Health, Technical University of Munich / Helmholtz Munich; German Center for Infection Research (DZIF), Munich partner site. Electronic address: protzer@tum.de.
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              Text: 2026 Jun 30
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