Vaccination elicits HIV broadly neutralizing antibodies in primates.

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Title: Vaccination elicits HIV broadly neutralizing antibodies in primates.
Authors: Steichen JM; Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, CA, USA.; IAVI Neutralizing Antibody Center, The Scripps Research Institute, La Jolla, CA, USA.; Consortium for HIV/AIDS Vaccine Development, The Scripps Research Institute, La Jolla, CA, USA., Madden PJ; Consortium for HIV/AIDS Vaccine Development, The Scripps Research Institute, La Jolla, CA, USA.; Center for Vaccine Innovation, La Jolla Institute for Immunology, La Jolla, CA, USA., Flynn CT; IAVI Neutralizing Antibody Center, The Scripps Research Institute, La Jolla, CA, USA.; Consortium for HIV/AIDS Vaccine Development, The Scripps Research Institute, La Jolla, CA, USA., Phulera S; IAVI Neutralizing Antibody Center, The Scripps Research Institute, La Jolla, CA, USA.; Consortium for HIV/AIDS Vaccine Development, The Scripps Research Institute, La Jolla, CA, USA.; Department of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, CA, USA., Shil M; Consortium for HIV/AIDS Vaccine Development, The Scripps Research Institute, La Jolla, CA, USA.; Center for Vaccine Innovation, La Jolla Institute for Immunology, La Jolla, CA, USA., Kalyuzhniy O; Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, CA, USA.; IAVI Neutralizing Antibody Center, The Scripps Research Institute, La Jolla, CA, USA.; Consortium for HIV/AIDS Vaccine Development, The Scripps Research Institute, La Jolla, CA, USA., Liguori A; Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, CA, USA.; IAVI Neutralizing Antibody Center, The Scripps Research Institute, La Jolla, CA, USA.; Consortium for HIV/AIDS Vaccine Development, The Scripps Research Institute, La Jolla, CA, USA., Kifude C; IAVI Neutralizing Antibody Center, The Scripps Research Institute, La Jolla, CA, USA.; Consortium for HIV/AIDS Vaccine Development, The Scripps Research Institute, La Jolla, CA, USA., Sewall LM; IAVI Neutralizing Antibody Center, The Scripps Research Institute, La Jolla, CA, USA.; Consortium for HIV/AIDS Vaccine Development, The Scripps Research Institute, La Jolla, CA, USA.; Department of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, CA, USA., Cottrell CA; Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, CA, USA.; IAVI Neutralizing Antibody Center, The Scripps Research Institute, La Jolla, CA, USA.; Consortium for HIV/AIDS Vaccine Development, The Scripps Research Institute, La Jolla, CA, USA., Ma KM; Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, CA, USA.; IAVI Neutralizing Antibody Center, The Scripps Research Institute, La Jolla, CA, USA.; Consortium for HIV/AIDS Vaccine Development, The Scripps Research Institute, La Jolla, CA, USA., Baboo S; Consortium for HIV/AIDS Vaccine Development, The Scripps Research Institute, La Jolla, CA, USA.; Department of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, CA, USA., Diedrich JK; Department of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, CA, USA., McKenney K; IAVI Neutralizing Antibody Center, The Scripps Research Institute, La Jolla, CA, USA.; Consortium for HIV/AIDS Vaccine Development, The Scripps Research Institute, La Jolla, CA, USA., deCamp AC; Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Center, Seattle, WA, USA., Carnathan DG; Emory National Primate Research Center and Emory Vaccine Center, Emory University School of Medicine, Atlanta, GA, USA., Phung I; Consortium for HIV/AIDS Vaccine Development, The Scripps Research Institute, La Jolla, CA, USA.; Center for Vaccine Innovation, La Jolla Institute for Immunology, La Jolla, CA, USA., Ramezani-Rad P; Consortium for HIV/AIDS Vaccine Development, The Scripps Research Institute, La Jolla, CA, USA.; Center for Vaccine Innovation, La Jolla Institute for Immunology, La Jolla, CA, USA., Marina-Zárate E; Consortium for HIV/AIDS Vaccine Development, The Scripps Research Institute, La Jolla, CA, USA.; Center for Vaccine Innovation, La Jolla Institute for Immunology, La Jolla, CA, USA., Freeman B; Consortium for HIV/AIDS Vaccine Development, The Scripps Research Institute, La Jolla, CA, USA.; Center for Vaccine Innovation, La Jolla Institute for Immunology, La Jolla, CA, USA., Xie Z; The Ragon Institute of Mass General, MIT, and Harvard, Cambridge, MA, USA., Lee JH; Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, CA, USA.; IAVI Neutralizing Antibody Center, The Scripps Research Institute, La Jolla, CA, USA.; Consortium for HIV/AIDS Vaccine Development, The Scripps Research Institute, La Jolla, CA, USA.; Regeneron Pharmaceuticals, Inc., Tarrytown, NY, USA., Sincomb T; Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, CA, USA.; IAVI Neutralizing Antibody Center, The Scripps Research Institute, La Jolla, CA, USA.; Consortium for HIV/AIDS Vaccine Development, The Scripps Research Institute, La Jolla, CA, USA., Phelps N; Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, CA, USA.; IAVI Neutralizing Antibody Center, The Scripps Research Institute, La Jolla, CA, USA.; Consortium for HIV/AIDS Vaccine Development, The Scripps Research Institute, La Jolla, CA, USA., Lu D; Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, CA, USA.; IAVI Neutralizing Antibody Center, The Scripps Research Institute, La Jolla, CA, USA.; Consortium for HIV/AIDS Vaccine Development, The Scripps Research Institute, La Jolla, CA, USA., Goodwin D; Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, CA, USA.; IAVI Neutralizing Antibody Center, The Scripps Research Institute, La Jolla, CA, USA.; Consortium for HIV/AIDS Vaccine Development, The Scripps Research Institute, La Jolla, CA, USA., Tingle R; Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, CA, USA.; IAVI Neutralizing Antibody Center, The Scripps Research Institute, La Jolla, CA, USA.; Consortium for HIV/AIDS Vaccine Development, The Scripps Research Institute, La Jolla, CA, USA., Adachi Y; Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, CA, USA.; IAVI Neutralizing Antibody Center, The Scripps Research Institute, La Jolla, CA, USA.; Consortium for HIV/AIDS Vaccine Development, The Scripps Research Institute, La Jolla, CA, USA., Alavi N; Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, CA, USA.; IAVI Neutralizing Antibody Center, The Scripps Research Institute, La Jolla, CA, USA.; Consortium for HIV/AIDS Vaccine Development, The Scripps Research Institute, La Jolla, CA, USA., Tran J; Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, CA, USA.; IAVI Neutralizing Antibody Center, The Scripps Research Institute, La Jolla, CA, USA.; Consortium for HIV/AIDS Vaccine Development, The Scripps Research Institute, La Jolla, CA, USA., Tran AS; IAVI Neutralizing Antibody Center, The Scripps Research Institute, La Jolla, CA, USA.; Consortium for HIV/AIDS Vaccine Development, The Scripps Research Institute, La Jolla, CA, USA.; Department of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, CA, USA., Nascimento A; Emory National Primate Research Center and Emory Vaccine Center, Emory University School of Medicine, Atlanta, GA, USA., Sovie C; Emory National Primate Research Center and Emory Vaccine Center, Emory University School of Medicine, Atlanta, GA, USA., Bader DLV; Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, CA, USA.; IAVI Neutralizing Antibody Center, The Scripps Research Institute, La Jolla, CA, USA.; Consortium for HIV/AIDS Vaccine Development, The Scripps Research Institute, La Jolla, CA, USA.; Department of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, CA, USA., Voic H; IAVI Neutralizing Antibody Center, The Scripps Research Institute, La Jolla, CA, USA.; Consortium for HIV/AIDS Vaccine Development, The Scripps Research Institute, La Jolla, CA, USA., Zhou X; IAVI Neutralizing Antibody Center, The Scripps Research Institute, La Jolla, CA, USA.; Consortium for HIV/AIDS Vaccine Development, The Scripps Research Institute, La Jolla, CA, USA., Pixton G; Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, CA, USA.; IAVI Neutralizing Antibody Center, The Scripps Research Institute, La Jolla, CA, USA.; Consortium for HIV/AIDS Vaccine Development, The Scripps Research Institute, La Jolla, CA, USA., Walsh A; Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, CA, USA., Melo MB; Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, CA, USA., Schiffner T; Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, CA, USA.; IAVI Neutralizing Antibody Center, The Scripps Research Institute, La Jolla, CA, USA.; Consortium for HIV/AIDS Vaccine Development, The Scripps Research Institute, La Jolla, CA, USA., Batista FD; The Ragon Institute of Mass General, MIT, and Harvard, Cambridge, MA, USA.; Department of Biology, Massachusetts Institute of Technology, Cambridge, MA, USA., Burton DR; Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, CA, USA.; IAVI Neutralizing Antibody Center, The Scripps Research Institute, La Jolla, CA, USA.; Consortium for HIV/AIDS Vaccine Development, The Scripps Research Institute, La Jolla, CA, USA., Irvine DJ; Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, CA, USA.; Consortium for HIV/AIDS Vaccine Development, The Scripps Research Institute, La Jolla, CA, USA.; Howard Hughes Medical Institute, Chevy Chase, MD, USA., Paulson JC; Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, CA, USA.; Consortium for HIV/AIDS Vaccine Development, The Scripps Research Institute, La Jolla, CA, USA., Yates JR 3rd; Consortium for HIV/AIDS Vaccine Development, The Scripps Research Institute, La Jolla, CA, USA.; Department of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, CA, USA., Ozorowski G; IAVI Neutralizing Antibody Center, The Scripps Research Institute, La Jolla, CA, USA.; Consortium for HIV/AIDS Vaccine Development, The Scripps Research Institute, La Jolla, CA, USA.; Department of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, CA, USA., Ward AB; IAVI Neutralizing Antibody Center, The Scripps Research Institute, La Jolla, CA, USA.; Consortium for HIV/AIDS Vaccine Development, The Scripps Research Institute, La Jolla, CA, USA.; Department of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, CA, USA., Silvestri G; Emory National Primate Research Center and Emory Vaccine Center, Emory University School of Medicine, Atlanta, GA, USA., Crotty S; Consortium for HIV/AIDS Vaccine Development, The Scripps Research Institute, La Jolla, CA, USA. shane@lji.org.; Center for Vaccine Innovation, La Jolla Institute for Immunology, La Jolla, CA, USA. shane@lji.org.; Division of Infectious Diseases and Global Public Health, Department of Medicine, University of California San Diego, La Jolla, CA, USA. shane@lji.org., Schief WR; Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, CA, USA. schief@scripps.edu.; IAVI Neutralizing Antibody Center, The Scripps Research Institute, La Jolla, CA, USA. schief@scripps.edu.; Consortium for HIV/AIDS Vaccine Development, The Scripps Research Institute, La Jolla, CA, USA. schief@scripps.edu.; Moderna, Inc., Cambridge, MA, USA. schief@scripps.edu.
Source: Nature [Nature] 2026 Jun 30. Date of Electronic Publication: 2026 Jun 30.
Publication Type: Journal Article
Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 0410462 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-4687 (Electronic) Linking ISSN: 00280836 NLM ISO Abbreviation: Nature Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1476-4687
DOI:10.1038/s41586-026-10837-5